224779-27-5

• 常用中文名：叔-丁基 3-羟基-1,2,3,6-四氢吡啶-1-甲酸基酯
• 常用英文名：n-boc-3-hydroxy-1,2,3,6-tetrahydropyridine
• CAS号：224779-27-5
• 分子式：C₁₀H₁₇NO₃
• 分子量：199.24700
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 羟基吡啶
• 发布时间：2018-12-23 07:35:12
• 更新时间：2026-07-03 22:38:34

名称

• 中文名: 1-Boc-3-羟基-1,2,3,6-四氢吡啶
• 英文名: tert-butyl 3-hydroxy-3,6-dihydro-2H-pyridine-1-carboxylate
• 中文别名: 5-羟基-5,6-二氢吡啶-1(2H)-羧酸叔丁酯; 1-叔丁基-3-羟基-1,2,3,6-四氢吡啶; 3-羟基-1,2,3,6-四氢吡啶-1-羧酸叔丁酯; 3-羟基-1,2,3,6-四氢吡啶-1-甲酸叔丁酯; 1-BOC-3-羟基-1,2,3,6-四氢吡啶; N-BOC-3-羟基-1,2,3,6-四氢吡啶
• 英文别名: N-BOC-3-HYDROXY-1,2,3,6-TETRAHYDROPYRIDINE ISO 9001：2015 REACH; tert-Butyl 5-hydroxy-5,6-dihydropyridine-1(2H)-cboxylate; tert-Butyl 3-hydroxy-1,2,3,6-tetrahydropyridine-1-cboxylate; tert-butyl 3-hydroxy-1,2,3,6-tetrahydropyridine-N-cboxylate; SKL015; N-tert-Butoxycbonyl-5-hydroxy-1,2,5,6-tetrahydropyridine; 3-hydroxy-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester; 1-Boc-3-hydroxy-1,2,3,6-tetrahydropyridine; Novobiocin Impurity 2; 3-HYDROXY-3,6-DIHYDRO-2H-PYRIDINE-1-CBOXYLIC ACID TERT-BUTYL ESTER; tert-butyl 3-hydroxy-1,2,3,6-tetrahydropyridine-N-carboxylate; tert-Butyl 3,6-dihydro-3-hydroxypyridine-1(2H)-cboxylate; tert-butyl 3-hydroxy-1,2,3,6-tetrahydropyridinecarboxylate; tert-Butyl 3,6-dihydro-3-hydroxypyridine-1(2H)-cboxylate, 1-(tert-Butoxycbonyl)-3-hydroxy-1,2,3,6-tetrahydropyridine; 3,6-DIHYDRO-3-HYDROXY-1(2H)-PYRIDINECBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER; N-BOC-3-HYDROXY-1,2,3,6-TETRAHYDROPYRIDINE; 1(2H)-Pyridinecboxylic acid, 3,6-dihydro-3-hydroxy-, 1,1-dimethylethyl ester; tert-butyl 3-hydroxy-3,6-dihydro-2H-pyridine-1-cboxylate; 1-Boc-3-hydroxy-1,2,3,6-tetrahydro-pyridine; 3-Hydroxy-1,2,3,6-tetrahydropyridine, N-BOC protected; ert-butyl3-hydroxy-3,6-dihydro-2H-pyridine-1-cboxylate

物化性质

• 密度: 1.138g/cm3
• 沸点: 295.9ºC at 760mmHg
• 分子式: C₁₀H₁₇NO₃
• 分子量: 199.24700
• 闪点: 132.8ºC
• 精确质量: 199.12100
• PSA: 49.77000
• LogP: 1.09210
• 外观性状: Light-Yellow Solid
• 蒸汽压: 0.000153mmHg at 25°C
• 折射率: 1.513
• 储存条件: 2-8℃

安全

• 危害码 (欧洲): Xi: Irritant;
• 海关编码: 2933399090

合成路线

224779-26-4 ~98% 224779-27-5

文献：Takahata, Hiroki; Suto, Yumiko; Kato, Erina; Yoshimura, Yuichi; Ouchi, Hidekazu Advanced Synthesis and Catalysis, 2007 , vol. 349, # 4-5 p. 685 - 693

120568-74-3 ~% 224779-27-5

文献：Synlett, , # 5 p. 741 - 744

24424-99-5 ~% 224779-27-5

文献：Advanced Synthesis and Catalysis, , vol. 349, # 4-5 p. 685 - 693

109384-19-2 ~% 224779-27-5

文献：WO2013/138210 A1, ;

141699-59-4 ~% 224779-27-5

文献：WO2013/138210 A1, ;

85838-94-4 ~% 224779-27-5

文献：WO2013/138210 A1, ;

161157-50-2 ~% 224779-27-5

文献：WO2013/138210 A1, ;

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%