13067-19-1

• 常用中文名：N-(苯并[d][1,3]二氧戊环-5-基)乙酰胺
• 常用英文名：Acetamide,N-1,3-benzodioxol-5-yl-
• CAS号：13067-19-1
• 分子式：C₉H₉NO₃
• 分子量：179.17300
• 发布时间：2018-03-18 08:00:00
• 更新时间：2024-01-08 18:53:05

名称

• 中文名: 3,4-亚甲基二氧基乙酰苯胺
• 英文名: N-(1,3-benzodioxol-5-yl)acetamide
• 英文别名: 5-acetamido-1,3-benzodioxole; Acetamide,N-1,3-benzodioxol-5-yl; 5-acetamino-1,3-benzodioxole; N-1,3-Benzodioxol-5-ylacetamide

物化性质

• 密度: 1.34g/cm3
• 沸点: 367.4ºC at 760mmHg
• 分子式: C₉H₉NO₃
• 分子量: 179.17300
• 闪点: 176ºC
• 精确质量: 179.05800
• PSA: 47.56000
• LogP: 1.44670
• 外观性状: 灰白色固体
• 蒸汽压: 1.37E-05mmHg at 25°C
• 折射率: 1.615
• 储存条件: 室温，密封，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AB4542510 CHEMICAL NAME : Acetamide, N-1,3-benzodioxol-5-yl- CAS REGISTRY NUMBER : 13067-19-1 LAST UPDATED : 199606 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C9-H9-N-O3 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0052887 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 410 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0052887 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 660 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0052887 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0052887

安全

• 海关编码: 2932999099

合成路线

108-24-7 14268-66-7 ~94% 13067-19-1

文献：Elban, Mark A.; Sun, Wenyue; Eisenhauer, Brian M.; Gao, Rong; Hecht, Sidney M. Organic Letters, 2006 , vol. 8, # 16 p. 3513 - 3516

14268-66-7 75-36-5 ~40% 13067-19-1

文献：Luzzio, Michael J.; Besterman, Jeffrey M.; Emerson, David L.; Evans, Michael G.; Lackey, Karen; et al. Journal of Medicinal Chemistry, 1995 , vol. 38, # 3 p. 395 - 401

14268-66-7 ~95% 1061318-82-8 13067-19-1

文献：Cai, Xiong; Qian, Changgeng Patent: US2010/184801 A1, 2010 ;

14268-66-7 ~53% 13067-19-1

文献：Takasago International Corporation Patent: US6228547 B1, 2001 ;

108-24-7 14268-66-7 64-19-7 ~93% 13067-19-1

文献：Cai, Xiong; Qian, Changgeng; Zhai, Haixiao Patent: US2008/234314 A1, 2008 ; Location in patent: Page/Page column 59 ; US 20080234314 A1

62681-68-9 ~98% 13067-19-1

文献：Furuya, Yoshiro; Ishihara, Kazuaki; Yamamoto, Hisashi Journal of the American Chemical Society, 2005 , vol. 127, # 32 p. 11240 - 11241

2620-44-2 ~% 13067-19-1

文献：Hoffmann-La Roche Inc. Patent: US4435406 A1, 1984 ;

108-05-4 14268-66-7 ~63% 13067-19-1

文献：Lal, Samridhi; Snape, Timothy J. Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 83, p. 80 - 86

108-24-7 ~% 13067-19-1

文献：Perkin,W. H.; Robinson; Thomas Journal of the Chemical Society, 1909 , vol. 95, p. 1978,1983 Full Text Show Details Rupe; v. Majewski Chemische Berichte, 1900 , vol. 33, p. 3405

海关

海关编码	2932999099
中文概述	2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%