3251-23-8

• 常用中文名：硝酸铜
• 常用英文名：Copper dinitrate
• CAS号：3251-23-8
• 分子式：CuN₂O₆
• 分子量：187.556
• 相关类别： 无机化工 无机盐 金属硝酸盐及亚硝酸盐
• 发布时间：2018-06-12 05:28:17
• 更新时间：2024-01-04 11:30:55
• 【用途一】
  用作分析试剂及氧化剂

名称

• 中文名: 硝酸铜
• 英文名: copper(II) nitrate
• 中文别名: 硝酸銅
• 英文别名: claycop; copper(2+)nitrate; cupricdinitrate; EINECS 221-838-5; Kupfer(II)-nitrat; copper nitrate; Copper(2+) nitrate; MFCD00010967; Copperbis(nitrate); Cupric dinitrate; COPPER (II) NITRATE; Copper(2+) dinitrate; Cu(NO3)2; Copper dinitrate

物化性质

• 密度: 1.00 g/mL at 20 °C
• 沸点: 83ºC at 760 mmHg
• 熔点: 115°C
• 分子式: CuN₂O₆
• 分子量: 187.556
• 精确质量: 186.905243
• PSA: 137.76000
• LogP: 0.56570
• 外观性状: 蓝色结晶固体
• 储存条件: 库房通风低温干燥,轻装轻卸,与有机物、还原剂、硫、磷易燃物分开存放
• 稳定性: Stable. Oxidant. Incompatible with combustible materials.
• 水溶解性: Soluble
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:0

  3.氢键受体数量:6

  4.可旋转化学键数量:0

  5.互变异构体数量:无

  6.拓扑分子极性表面积126

  7.重原子数量:9

  8.表面电荷:0

  9.复杂度:18.8

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:3

MSDS

Name: Copper(II) nitrate trihydrate p.a. Material Safety Data Sheet Synonym: Cupric nitrate trihydrate CAS: 3251-23-8 Section 1 - Chemical Product MSDS Name:Copper(II) nitrate trihydrate p.a. Material Safety Data Sheet Synonym:Cupric nitrate trihydrate Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 3251-23-8 Copper(II) nitrate trihydrate >99 unlisted Hazard Symbols: XN O Risk Phrases: 22 36/38 8 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful if swallowed. Irritating to eyes and skin. Contact with combustible material may cause fire. Potential Health Effects Eye: Contact with eyes may cause severe irritation, and possible eye burns. Contact may cause ulceration of the conjunctiva and cornea. Skin: May cause severe irritation and possible burns. May cause dermatitis. May cause skin discoloration. Ingestion: May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns. May cause liver and kidney damage. May cause hemorrhaging of the digestive tract. Inhalation: May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, tachycardia, dyspnea (labored breathing), and death. May cause ulceration and perforation of the nasal septum if inhaled in excessive quantities. May cause severe irritation of the upper respiratory tract with pain, burns, and inflammation. Chronic: Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. May cause liver and kidney damage. Individuals with Wilson's disease are unable to metabolize copper. Thus, copper accumulates in various tissues and may result in liver, kidney, and brain damage. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Call a poison control center. If swallowed, do not induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. Get medical aid. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Antidote: The use of d-Penicillamine as a chelating agent should be determined by qualified medical personnel. Section 5 - FIRE FIGHTING MEASURES General Information: Strong oxidizer. Contact with other material may cause fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Wear appropriate protective clothing to prevent contact with skin and eyes. Wear a self-contained breathing apparatus (SCBA) to prevent contact with thermal decomposition products. Extinguishing Media: Use extinguishing media most appropriate for the surrounding fire. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Contents may develop pressure upon prolonged storage. Keep away from heat, sparks and flame. Avoid contact with clothing and other combustible materials. Do not get on skin or in eyes. Do not ingest or inhale. Storage: Keep away from heat, sparks, and flame. Do not store near combustible materials. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Local exhaust ventilation may be necessary to control any air contaminants to within their TLVs during the use of this product. Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Exposure Limits CAS# 3251-23-8: CAS# 10031-43-3: United Kingdom, WEL - TWA: (listed as copper): 0.2 mg/m3 TWA (fum 1 mg/m3 TWA (dust and mist) United Kingdom, WEL - STEL: (listed as copper): 0.6 mg/m3 STEL (fume); 2 mg/m3 STEL (dust and mist) United States OSHA: 0.1 mg/m3 TWA (fume); 1 mg/m3 TWA (dusts and mists) (listed under Copper). Belgium - TWA: (listed as copper): 0.2 mg/m3 VLE (fume); 1 mg/m3 (dust and mist) France - VME: (listed as copper): 0.2 mg/m3 VME (fume); 1 mg/m3 V (dust, as Cu) France - VLE: (listed as copper): 2 mg/m3 VLE (dust, as Cu) Germany: (listed as copper): 0.2 mg/m3 VME (fume); 1 mg/m3 VME (d as Cu) Malaysia: (listed as copper): 0.2 mg/m3 TWA (fume, as Cu); 1 mg/m TWA (dust and mist, as Cu) Netherlands: (listed as copper): 0.2 mg/m3 MAC (smoke); 1 mg/m3 M (dust) Russia: (listed as copper): 1 mg/m3 TWA (dust) Russia: (listed as copper): 0.5 mg/m3 STEL (dust) Spain: (listed as copper): 0.2 mg/m3 VLA-ED (fume); 1 mg/m3 VLA-E (dust and mist, as Cu) Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: blue Odor: odorless pH: 4.0 for 0.2M soln. Vapor Pressure: Not applicable. Viscosity: Not available. Boiling Point: Not applicable. Freezing/Melting Point: 114 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Not available. Solubility in water: Soluble in water. Specific Gravity/Density: 2.05 Molecular Formula: Cu(NO3)2.3H2O Molecular Weight: 241.60 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, combustible materials, reducing agents, strong oxidants, organic matter. Incompatibilities with Other Materials: Reducing agents, combustible materials, potassium ferrocyanide, ether, tin. Ignites paper spontaneously in the presence of moisture. Hazardous Decomposition Products: Oxides of nitrogen, irritating and toxic fumes and gases, copper fumes. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 3251-23-8: QU7400000 CAS# 10031-43-3: GL7875000 LD50/LC50: CAS# 3251-23-8: Draize test, rabbit, eye: 100 mg Severe; Draize test, rabbit, skin: 500 mg Severe; Oral, mouse: LD50 = 430 mg/kg; Oral, rat: LD50 = 794 mg/kg; Oral, rat: LD50 = 940 mg/kg. CAS# 10031-43-3: Oral, rat: LD50 = 940 mg/kg. Carcinogenicity: Cupric nitrate - Not listed by ACGIH, IARC, or NTP. Copper(II) nitrate trihydrate - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: NITRATES, INORGANIC, N.O.S. Hazard Class: 5.1 UN Number: 1477 Packing Group: II IMO Shipping Name: NITRATES, INORGANIC, N.O.S. Hazard Class: 5.1 UN Number: 1477 Packing Group: II RID/ADR Shipping Name: NITRATES, INORGANIC, N.O.S. Hazard Class: 5.1 UN Number: 1477 Packing group: II USA RQ: CAS# 3251-23-8: 100 lb final RQ; 45.4 kg final RQ Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN O Risk Phrases: R 22 Harmful if swallowed. R 36/38 Irritating to eyes and skin. R 8 Contact with combustible material may cause fire. Safety Phrases: S 17 Keep away from combustible material. S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 3251-23-8: No information available. CAS# 10031-43-3: 2 Canada CAS# 3251-23-8 is listed on Canada's DSL List. CAS# 3251-23-8 is listed on Canada's Ingredient Disclosure List. CAS# 10031-43-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 3251-23-8 is listed on the TSCA inventory. CAS# 10031-43-3 is not on the TSCA Inventory because it is a hydrate. It is considered to be listed if the CAS number for the anhydrous form is on the inventory (40CFR720.3(u)(2)). SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QU7400000 CHEMICAL NAME : Nitric acid, copper(2+) salt CAS REGISTRY NUMBER : 3251-23-8 LAST UPDATED : 199712 DATA ITEMS CITED : 42 MOLECULAR FORMULA : N2-O6.Cu MOLECULAR WEIGHT : 187.56 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit REFERENCE : FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,563,1982 TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit REFERENCE : FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,573,1982 TYPE OF TEST : Rinsed with water ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit REFERENCE : FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,573,1982 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 794 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold REFERENCE : INJPD2 Indian Journal of Pharmacology. (Dept. of Pharmacology, Baranas Hindu Univ., Varanasi 221 005, India) V.1- 1968(?)- Volume(issue)/page/year: 23,153,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold REFERENCE : INJPD2 Indian Journal of Pharmacology. (Dept. of Pharmacology, Baranas Hindu Univ., Varanasi 221 005, India) V.1- 1968(?)- Volume(issue)/page/year: 23,153,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 14700 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold REFERENCE : INJPD2 Indian Journal of Pharmacology. (Dept. of Pharmacology, Baranas Hindu Univ., Varanasi 221 005, India) V.1- 1968(?)- Volume(issue)/page/year: 23,153,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 430 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold REFERENCE : INJPD2 Indian Journal of Pharmacology. (Dept. of Pharmacology, Baranas Hindu Univ., Varanasi 221 005, India) V.1- 1968(?)- Volume(issue)/page/year: 23,153,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 17100 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold REFERENCE : INJPD2 Indian Journal of Pharmacology. (Dept. of Pharmacology, Baranas Hindu Univ., Varanasi 221 005, India) V.1- 1968(?)- Volume(issue)/page/year: 23,153,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 23300 ug/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold REFERENCE : INJPD2 Indian Journal of Pharmacology. (Dept. of Pharmacology, Baranas Hindu Univ., Varanasi 221 005, India) V.1- 1968(?)- Volume(issue)/page/year: 23,153,1991 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-AUSTRALIA:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-AUSTRALIA:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-BELGIUM:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-BELGIUM:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-DENMARK:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-DENMARK:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-FINLAND:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-FINLAND:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-FRANCE:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-FRANCE:TWA 1 mg(Cu)/m3;STEL 2 mg(Cu)/m3 (dust) JAN 1993 OEL-GERMANY:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-GERMANY:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-HUNGARY:TWA 0.2 mg(Cu)/m3;STEL 0.4 mg(Cu)/m3 (dust) JAN 1993 OEL-INDIA:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-THE NETHERLANDS:TWA 02 mg(Cu)/m3 (fume) JAN 1993 OEL-THE NETHERLANDS:TWA 1 mg(Cu)/m3 (dust) JAN 1993 OEL-THE PHILIPPINES:TWA 1.0 mg(Cu)/m3 (fume) JAN 1993 OEL-POLAND:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-RUSSIA:STEL 0.5 ppm (1 mg(Cu)/m3) (dust) JAN 1993 OEL-SWEDEN:TWA 0.2 mg(Cu)/m3 (resp. dust) JAN 1993 OEL-SWEDEN:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-SWEDEN:TWA 1 mg(Cu)/m3 (total dust) JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg(Cu)/m3;STEL 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-SWITZERLAND:TWA 1 mg(Cu)/m3;STEL 1 mg(Cu)/m3 JAN 1993 OEL-THAILAND:TWA 0.1 mg(Cu)/m3 (fume) JAN 1993 OEL-THAILAND:TWA 1 mg(Cu)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.2 mg(Cu)/m3 (fume) JAN 1993 OEL-UNITED KINGDOM:TWA 1 mg(Cu)/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84335 No. of Facilities: 97 (estimated) No. of Industries: 6 No. of Occupations: 8 No. of Employees: 738 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84335 No. of Facilities: 844 (estimated) No. of Industries: 19 No. of Occupations: 23 No. of Employees: 13313 (estimated) No. of Female Employees: 1746 (estimated)

安全

• 危害码 (欧洲): O: Oxidizing agent;C: Corrosive;Xi: Irritant;
• 风险声明 (欧洲): R8;R22;R34
• 安全声明 (欧洲): S53-S17-S26-S36/37/39-S45-S36
• 危险品运输编码: UN 3085 5.1/PG 3
• WGK德国: 3
• 包装等级: II
• 危险类别: 5.1
• 海关编码: 2834299090

制备

制法Cu+3N₂O₄→Cu(NO₃)₂·N₂O₄+2NO

Cu(NO₃)₂·N₂O₄→Cu(NO₃)₂+N₂O₄

从钢瓶中放出20mL N₂O₄于图中的反应管A中。然后加入铜条和20mL醋酸乙酯，在室温下放置4h，有沉淀Cu(NO₃)₂·N₂O₄析出，取下反应管迅速除去未反应的金属铜并加入20mL N₂O₄。装回反应管，并将仪器倒过来抽吸，取下反应管A，用15mL N₂O₄洗涤沉淀。取走滤液管C，将生成的Cu(NO₃)₂·N₂O₄倒入另一个干燥管A中。晶体上方塞紧一小块玻璃棉，将此管连接到高真空线上，在1.33Pa下用油浴(浸没到玻璃棉上方)加热到120℃，化合物分解为无水Cu(NO₃)₂，慢慢加热到200℃硝酸铜升华于管壁上方，收集。

精制法用热的发烟硝酸对市售的三水合硝酸铜进行再结晶，则得到无水硝酸铜。

用3%左右的稀硝酸对市售的三水合硝酸铜进行再结晶时，在冰冷却下则析出六水合物，而在30℃以上则析出三水合物。

海关

海关编码	2834299090