26378-53-0

• 常用中文名：2-(2-氯苯氧基)乙胺
• 常用英文名：2-(2-Chlorophenoxy)ethanamine
• CAS号：26378-53-0
• 分子式：C₈H₁₀ClNO
• 分子量：171.624
• 发布时间：2018-06-02 08:00:00
• 更新时间：2024-01-15 09:26:46

名称

• 中文名: 2-(2-氯苯氧基)乙胺
• 英文名: 2-(2-chlorophenoxy)ethanamine
• 英文别名: 2-(2-chlorophenoxy)-1-ethanamine; F9995-0097; 2-(2-Chloro-phenoxy)-ethylamine; 2-((5,5-DIMETHYL-3-OXOCYCLOHEX-1-ENYL)AMINO)-BENZOIC ACID; 2-(2-Chlorophenoxy)ethylamine; MFCD00125294; 2-(2-Chlorophenoxy)ethanamine; Ethanamine, 2-(2-chlorophenoxy)-

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 266.2±20.0 °C at 760 mmHg
• 熔点: 39-40°C
• 分子式: C₈H₁₀ClNO
• 分子量: 171.624
• 闪点: 114.8±21.8 °C
• 精确质量: 171.045090
• PSA: 35.25000
• LogP: 1.44
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.545
• 储存条件:

  保持贮藏器密封

  放入紧密的贮藏器内，储存在阴凉，干燥的地方

• 稳定性:

  如果遵照规格使用和储存则不会分解

  避免接触氧化物，酸
• 分子结构:

  1、 摩尔折射率：45.99

  2、 摩尔体积（m³/mol）：145.5

  3、 等张比容（90.2K）：368.6

  4、 表面张力（dyne/cm）：41.1

  5、 极化率（10 ^-24cm ³）：18.23

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:2

  4.可旋转化学键数量:3

  5.互变异构体数量:无

  6.拓扑分子极性表面积35.2

  7.重原子数量:11

  8.表面电荷:0

  9.复杂度:110

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状： 未确定

  2. 密度（g/mL,25/4℃）：未确定

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：未确定

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC,5.2kPa）：未确定

  7. 折射率：未确定

  8. 闪点（ºC）：未确定

  9. 比旋光度（º）：未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（kPa,25ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：未确定

MSDS

Name: 2-(2-Chlorophenoxy)ethylamine, 97% Material Safety Data Sheet Synonym: CAS: 26378-53-0 Section 1 - Chemical Product MSDS Name: 2-(2-Chlorophenoxy)ethylamine, 97% Material Safety Data Sheet Synonym: SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 26378-53-0 2-(2-Chlorophenoxy)ethylamine 97% unlisted Hazard Symbols: C Risk Phrases: 34 SECTION 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Causes burns.Air sensitive. Potential Health Effects Eye: Causes eye burns. Skin: Causes skin burns. Ingestion: Causes gastrointestinal tract burns. Inhalation: Causes chemical burns to the respiratory tract. Chronic: Not available. SECTION 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Do not induce vomiting. Get medical aid immediately. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. SECTION 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use foam, dry chemical, or carbon dioxide. SECTION 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. SECTION 7 - HANDLING and STORAGE Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Store under an inert atmosphere. SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 26378-53-0: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Liquid Color: colorless Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 115 - 117 deg C @5mmHg Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C8H10ClNO Molecular Weight: 171.63 SECTION 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials, exposure to air. Incompatibilities with Other Materials: Oxidizing agents, acids, acid chlorides. Hazardous Decomposition Products: Hydrogen chloride, chlorine, nitrogen oxides, carbon monoxide, carbon dioxide, acrid smoke and fumes. Hazardous Polymerization: Has not been reported SECTION 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 26378-53-0 unlisted. LD50/LC50: Not available. Carcinogenicity: 2-(2-Chlorophenoxy)ethylamine - Not listed by ACGIH, IARC, or NTP. SECTION 12 - ECOLOGICAL INFORMATION SECTION 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. SECTION 14 - TRANSPORT INFORMATION IATA Shipping Name: AMINES, LIQUID, CORROSIVE, N.O.S. Hazard Class: 8 UN Number: 2735 Packing Group: III IMO Shipping Name: AMINES, LIQUID, CORROSIVE, N.O.S. Hazard Class: 8 UN Number: 2735 Packing Group: III RID/ADR Shipping Name: AMINES, LIQUID, CORROSIVE, N.O.S. Hazard Class: 8 UN Number: 2735 Packing group: III SECTION 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 34 Causes burns. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 26378-53-0: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 26378-53-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 26378-53-0 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION MSDS Creation Date: 3/21/2003 Revision #0 Date: Original. The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no way shall the company be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if the company has been advised of the possibility of such damages. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 对水是稍微危害的，若无政府许可，勿将材料排入周围环境

安全

• 危害码 (欧洲): C:Corrosive;
• 风险声明 (欧洲): R34
• 安全声明 (欧洲): S26-S36/37/39
• 危险品运输编码: 2735
• 包装等级: III
• 危险类别: 8
• 海关编码: 2922299090

合成路线

66443-61-6 ~63% 26378-53-0

文献：Synthesis, , # 15 p. 2527 - 2534

18800-26-5 ~% 26378-53-0

文献：Chimica Therapeutica, , vol. 4, p. 334 - 343

95-57-8 ~% 26378-53-0

文献：Journal of Medicinal Chemistry, , vol. 47, # 8 p. 1900 - 1918

727368-76-5 ~% 26378-53-0

文献：Journal of Medicinal Chemistry, , vol. 47, # 8 p. 1900 - 1918

95-57-8 107-14-2 ~% 26378-53-0

文献：J. Med. Chem., , vol. 6, p. 705 - 711

上下游产品

上游产品  4
66443-61-6 18800-26-5 95-57-8 107-14-2
下游产品  2
5735-53-5 46322-18-3

海关

海关编码	2922299090
中文概述	2922299090. 其他氨基(萘酚、酚)及醚、酯〔包括它们的盐, 但含有一种以上含氧基的除外〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%