21243-18-5

• 常用中文名：6-氟-2,3-二氢-4H-硫代色烯-4-酮
• 常用英文名：6-fluorothio-4-chromanone
• CAS号：21243-18-5
• 分子式：C₉H₇FOS
• 分子量：182.21500
• 发布时间：2018-02-22 08:00:00
• 更新时间：2024-01-10 09:18:10

名称

• 中文名: 6-氟硫代-4-色原酮
• 英文名: 6-fluoro-2,3-dihydrothiochromen-4-one
• 中文别名: 6-氟-4-硫色满酮; 6-氟-2,3-二氢-4H-硫代色烯-4-酮
• 英文别名: 6-fluoro-2,3-dihydro-4H-1-benzothiopyran-4-one; 6-fluoro-3,4-dihydro-2H-1-benzothiopyran-4-one; MFCD00078488; 6-fluorothiochroman-4-one; 6-fluoro-4-thiochromanone; 6-fluoro-1-thiochroman-4-one; 6-Fluoro-4-oxothiochroman; 6-fluoro-2,3-dihydro-4h-thiochromen-4-one

物化性质

• 密度: 1.335 g/cm3
• 沸点: 304.3ºC at 760 mmHg
• 熔点: 89-92ºC
• 分子式: C₉H₇FOS
• 分子量: 182.21500
• 闪点: 137.8ºC
• 精确质量: 182.02000
• PSA: 42.37000
• LogP: 2.50420
• 蒸汽压: 0.000883mmHg at 25°C
• 折射率: 1.6
• 储存条件: 室温，干燥，密封

MSDS

Name: 6-Fluoro-2 3-dihydro-4h-thiochromen-4-one 95+% Material Safety Data Sheet Synonym: 6-Fluorothiochroman-4-on CAS: 21243-18-5 Section 1 - Chemical Product MSDS Name:6-Fluoro-2 3-dihydro-4h-thiochromen-4-one 95+% Material Safety Data Sheet Synonym:6-Fluorothiochroman-4-on Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 21243-18-5 6-Fluoro-2,3-dihydro-4H-thiochromen-4- 95+% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Store under an inert atmosphere. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 21243-18-5: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 89 - 92 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C9H7FOS Molecular Weight: 182 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, oxides of sulfur, carbon dioxide, hydrogen fluoride gas, acrid smoke and fumes. Hazardous Polymerization: Not available. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 21243-18-5 unlisted. LD50/LC50: Not available. Carcinogenicity: 6-Fluoro-2,3-dihydro-4H-thiochromen-4-one - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 21243-18-5: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 21243-18-5 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 21243-18-5 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36/37/39
• 海关编码: 2932999099

合成路线

19543-85-2 ~84% 21243-18-5

文献：Jia, Wei; Liu, Yajing; Li, Wei; Liu, Yan; Zhang, Dajun; Zhang, Peng; Gong, Ping Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 13 p. 4569 - 4574

371-42-6 ~% 21243-18-5

文献：Chinese Journal of Chemistry, , vol. 29, # 4 p. 757 - 764

3887-61-4 ~% 21243-18-5

文献：Journal of Chemical Research, , # 6 p. 394 - 395

上下游产品

上游产品  3
19543-85-2 371-42-6 3887-61-4
下游产品  7
22298-04-0 66892-63-5 52831-35-3 52831-37-5
52831-41-1 52831-42-2 52831-45-5

海关

海关编码	2932999099
中文概述	2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%