31687-58-8

• 常用中文名：双叔丁氧羰酰基组氨酸二环己胺盐
• 常用英文名：Boc-His(Boc)-OH DCHA
• CAS号：31687-58-8
• 分子式：C₂₈H₄₈N₄O₆
• 分子量：536.70400
• 相关类别： 生物化工 氨基酸及其衍生物 组氨酸类衍生物
• 发布时间：2018-08-01 13:45:41
• 更新时间：2026-07-04 20:49:06
• Boc His(Boc)-俄亥俄州。DCHA是组氨酸衍生物[1]。

名称

• 中文名: Boc-His(Boc)-OH 二环己基铵盐
• 英文名: N-cyclohexylcyclohexanamine,(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-[1-[(2-methylpropan-2-yl)oxycarbonyl]imidazol-4-yl]propanoic acid
• 中文别名: N,N'-二-BOC-L-组氨酸 二环己基铵盐; N-BOC-N'-BOC-L-组氨酸环己二胺盐; N,N'-二叔丁氧羰基-L-组氨酸二环己铵盐; NΑ,N(IM)-二叔丁氧羰基-L-组氨酸 二环己基铵盐; (S)-3-(1-(叔丁氧羰基)-1H-咪唑-4-基)-2-((叔丁氧羰基)氨基)丙酸二环己胺盐; BOC-组氨酸(BOC)-OH DCHA; N,1-双(叔丁氧羰基)-L-组氨酸双环己胺盐; BOC-HIS(BOC)-OH 二环己基铵盐; N,1-二-BOC-L-组氨酸 二环己基铵盐
• 英文别名: N-ALPHA-N-IM-DI-T-BOC-L-HISTIDINE DICYCLOHEXYLAMMONIUM SALT; N,1-Bis(tert-butoxycbonyl)-L-histidine dicyclohexylamine (1:1); BOC-HIS(BOC)-OH DCHA //BP; N-cyclohexylcyclohexanamine,(2S)-2-[(2-methylpropan-2-yl)oxycbonylamino]-3-[1-[(2-methylpropan-2-yl)oxycbonyl]imidazol-4-yl]propanoic acid; Boc-His(Z).DCHA; Boc-L-His(Boc)*DCHA; Boc-His(Boc)-OH·DCHA N-α,N-iM-di-Boc-L-histidine dicyclohexylaMine salt; N-α,N-im-di-Boc-L-histidine dicyclohexylamine sal; Boc-His(Boc)-OH·DCHA; N-a-N-im-di-t-Boc-L-Histidinedicyclochexylammoniumsalt; Boc(Nim-Boc)His-OH*DCHA; BOC-HIS(BOC)-OH DCHA; N-α-N-im-di-t-Boc-L-histidine dicyclochexylammonium salt; Boc-His(Boc)-OH. DCHA Novabiochem; N,N-di(tert-butoxycbonyl)-L-histidine dicyclohexylamine; Boc-His(Boc)-OH x DCHA ,(HPLC); 2-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]-3-[1-[(2-methylpropan-2-yl)oxy-oxomethyl]-4-imidazolyl]propanoic acid; BOC- HS(BOC) -OH DCHA; N-ALPHA,N-IM-DI-T-BUTOXYCBONYL-L-HISTIDINE DICYCLOHEXYLAMMONIUM SALT; BOC-L-HIS(BOC)-OH DCHA; Boc-His(Boc)-OH DCH; (2S)-3-{1-[(tert-butoxy)carbonyl]-1H-imidazol-4-yl}-2-{[(tert-butoxy)carbonyl]amino}propanoic acid; NIM-DI-BOC-L-HISTIDINE DCHA SALT; EINECS 250-764-6; N,N'-Di-Boc-L-histidine dicyclohexylaMMoniuM salt; Boc-His(Boc)-OH (dicyclohexylammonium) salt; N,1-bis(tert-butoxycbonyl)-L-histidine, compound with dicyclohexylamine (1:1); (Tert-Butoxy)carbonyl His(Boc)-OH·DCHA; N-ALPHA,N-IM-BIS-BOC-L-HISTIDINE DICYCLOHEXYLAMMONIUM SALT; N,1-Bis-Boc-L-histidine DCHA; N-α,N-im-di-Boc-L-histidine dicyclohexylamine salt; Nα,Nim-Bis-Boc-L-histidine dicyclohexylammonium salt; N-S-N(im)-di-tert-Boc-L-histidine dicyclohexylamine salt; NALPHA,Nim-Di-tert-butoxycbonyl-L-histidine dicyclohexylamine salt; Boc-His(Boc)-Ohcha; N-ALPHA-TERT-BUTYLOXYCBONYL-N-IM-TERT-BUTYLOXYCBONYL-L-HISTIDINE DICYCLOHEXYLAMINE; N-ALPHA-T-BUTYLOXYCBONYL-N-IM-T-BUTYLOXYCBONYL-L-HISTIDINE DICYCLOHEXYLAMINE; N-N(im)-di-t-Boc-L-histidineDicyclohexylaminesalt; N,1-Di-Boc-L-histidine dicyclohexylaMMoniuM salt; N-cyclohexylcyclohexanamine,(2S)-2-[(2-methylpropan-2-yl)oxycbonylamino]-3-[1-[(2-methylpropan-2-yl)oxycbonyl]imidazol-4-yl]propanoicaci; N-ALPHA,NIM-DI-BOC-L-HISTIDINE DICYCLOHEXYLAMINE SALT; N-α,N-im-di-Boc-L-histidine; Boc-His(Boc)-OH dicyclohexylamine salt; BOC-NIM-BOC-L-HISTIDINE DICYCLOHEXYLAMINE SALT; Boc-His(Boc).DCHA; Nα,Nim-Bis-Boc-L-histidine dicyclohexylammonium salt (HPLC); N,1-Bis(Boc)-L-histidine dicyclohexylamine salt

物化性质

• 沸点: 679.7ºC at 760 mmHg
• 熔点: 160-165ºC (dec.)
• 分子式: C₂₈H₄₈N₄O₆
• 分子量: 536.70400
• 闪点: 364.9ºC
• 精确质量: 536.35700
• PSA: 131.78000
• LogP: 6.20990
• 外观性状: 白色粉末
• 储存条件: -20°C

生物活性

• 描述: Boc His(Boc)-俄亥俄州。DCHA是组氨酸衍生物[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 体外研究: 氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。
• 参考文献:

  [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

安全

• 危害码 (欧洲): Xn
• 安全声明 (欧洲): 22-24/25
• WGK德国: 3

合成路线

24424-99-5 101-83-7 71-00-1 ~75% 31687-58-8

文献：Nguyen, Dung Le; Seyer, Rene; Heitz, Annie; Castro, Bertrand Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1025 - 1032

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