1231243-91-6

• 常用中文名：N-(4-((2-甲氧基乙基)(甲基)氨基)苯基)-2-苯基-5-(三氟甲基)噁唑-4-羧酰胺
• 常用英文名：SCD1 inhibitor
• CAS号：1231243-91-6
• 分子式：C₂₁H₂₀F₃N₃O₃
• 分子量：419.39700
• 发布时间：2018-07-25 22:32:57
• 更新时间：2024-02-04 18:10:59
• A novel stearoyl-CoA desaturase1 (SCD1) inhibitor.The compound exhibited robust in vivo activity with dose-dependent desaturation index lowering effects.

名称

• 中文名: N-(4-((2-甲氧基乙基)(甲基)氨基)苯基)-2-苯基-5-(三氟甲基)噁唑-4-羧酰胺
• 英文名: N-[4-[2-methoxyethyl(methyl)amino]phenyl]-2-phenyl-5-(trifluoromethyl)-1,3-oxazole-4-carboxamide
• 中文别名: N-[4-[(2-甲氧基乙基)甲基氨基]苯基]-2-苯基-5-(三氟甲基)-4-唑甲酰胺
• 英文别名: 2-phenyl-5-trifluoromethyloxazole-4-carboxylic acid {4-[(2-methoxyethyl)(methyl)amino]phenyl}amide; N-(4-((2-Methoxyethyl)(methyl)amino)phenyl)-2-phenyl-5-(trifluoromethyl)oxazole-4-carboxamide; 4-Oxazolecarboxamide, N-[4-[(2-methoxyethyl)methylamino]phenyl]-2-phenyl-5-(trifluoromethyl)-; SCD1 inhibitor

物化性质

• 密度: 1.3±0.1 g/cm3
• 分子式: C₂₁H₂₀F₃N₃O₃
• 分子量: 419.39700
• 精确质量: 419.14600
• PSA: 67.60000
• LogP: 2.86
• 折射率: 1.576
• 储存条件: -20°C，密闭，干燥

安全

• 海关编码: 2934999090

合成路线

151951-34-7 ~% 1231243-91-6

文献：Qian, Yimin; Wertheimer, Stanley J.; Ahmad, Mushtaq; Cheung, Adrian Wai-Hing; Firooznia, Fariborz; Hamilton, Matthew M.; Hayden, Stuart; Li, Shiming; Marcopulos, Nicholas; McDermott, Lee; Tan, Jenny; Yun, Weiya; Guo, Liang; Pamidimukkala, Anjula; Chen, Yingsi; Huang, Kuo-Sen; Ramsey, Gwendolyn B.; Whittard, Toni; Conde-Knape, Karin; Taub, Rebecca; Rondinone, Cristina M.; Tilley, Jefferson; Bolin, David Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2433 - 2446

350-46-9 ~% 1231243-91-6

文献：Qian, Yimin; Wertheimer, Stanley J.; Ahmad, Mushtaq; Cheung, Adrian Wai-Hing; Firooznia, Fariborz; Hamilton, Matthew M.; Hayden, Stuart; Li, Shiming; Marcopulos, Nicholas; McDermott, Lee; Tan, Jenny; Yun, Weiya; Guo, Liang; Pamidimukkala, Anjula; Chen, Yingsi; Huang, Kuo-Sen; Ramsey, Gwendolyn B.; Whittard, Toni; Conde-Knape, Karin; Taub, Rebecca; Rondinone, Cristina M.; Tilley, Jefferson; Bolin, David Journal of Medicinal Chemistry, 2011 , vol. 54, # 7 p. 2433 - 2446

上下游产品

上游产品  1
350-46-9
下游产品  0

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%