20850-49-1

• 常用中文名：3-甲基-2-(3,4-二甲氧基苯基)丁腈
• 常用英文名：UNII:1Z42YUG42K
• CAS号：20850-49-1
• 分子式：C₁₃H₁₇NO₂
• 分子量：219.280
• 发布时间：2018-12-17 09:12:35
• 更新时间：2026-07-17 04:15:34

名称

• 中文名: 3-甲基-2-(3,4-二甲氧基苯基)丁腈
• 英文名: 2-(3,4-Dimethoxyphenyl)-3-methylbutanenitrile
• 中文别名: 维拉帕米杂质11(维拉帕米杂质K); 盐酸维拉帕米杂质K 标准品; 2-(3,4-二甲氧基苯基)-Β-甲基丁腈; 维拉帕米杂质K; 维拉帕米杂质; 3,4-二甲氧基-Α-(1-甲基乙基)苯腈; 2-(3,4-二甲氧苯基)-3-甲基丁腈; 2-(3,4-二甲氧基苯基)-beta-甲基丁腈; 盐酸维拉帕米杂质K; Α-(3,4-二甲氧基苯基)异戊腈
• 英文别名: 3,4-Dimethoxy-α-(1-methylethyl)benzeneacetonitrile; a-Isopropylhomoveratronitrile; 2-(3,4-DiMethoxy phenyl)-β-Methylbutyronitrile; Verapamil Impurity K; Verapamil Hydrochloride Impurity K; 2-(3,4-Dimethoxyphenyl)-3-methylbutylnitrile; 20-1 3-Methyl-2-(3,4-dimethoxyphenyl)butyronitrile; 2-(3,4-Dimethoxy pheny)-3-methylbutyronitrile; (2RS)-2-(3,4-Dimethoxyphenyl)-3-met; 3-Methyl-2-(3,4-Dimethoxyphenyl)Butyronitrile(Verapamil Intermediate); BENZENEACETONITRILE,3,4-DIMETHOXY-A-(1-METHYLETHYL); 3,4-Dimethoxy-a-(1-methylethyl)benzeneacetonitrile; 2-(3, 4-Dimethoxyphenyl)-3-methylbutyronitril; 2-(3,4-Dimethoxyphenyl)-2-isopropylacetonitrile; 2-(3,4-Dimethoxyphenyl)-3-methyl-butanenitrile (Isopropyl Veratryle Cyanide) (IVC); Benzeneacetonitrile, 3,4-dimethoxy-α-(1-methylethyl); MFCD00800230; 2-(3,4-dimethoxy phenyl)-3-methyl butane nitrile (IVC); verapamil impurities878; 2-(3,4-DIMETHOXYPHENYL) (Isovetryl Cyanide) (IVC); 3,4-Dimethoxy-a-(1-methylethyl)-benzeneacetonitrile; 3,4-Dimethoxy-Alpha-(1-Methylethyl)Benzene Acetonitrile; alpha-Isopropyl homoveratronitrile; EINECS 244-082-8; α-Isopropyl-3,4-dimethoxybenzeneacetonitrile; Isopropyl Veratronitrile; BENZENEACETONITRILE, 3,4-DIMETHOXY-ALPHA-(1-METHYLETHYL); (-2-(3,4-Dimethoxyphenyl)-3-methylbutanenitrile; 2-(3,4-DIMETHOXY PHENYL)-ALPHA-METHYLBUTYRONITRILE; 3,4-Dimethoxy-alpha-(1-Methylethyl)benzonitrile; α-(3,4-Dimethoxyphenyl)isovaleronitrile; Verapamil hydrochloride Imp.K : (2RS)-2-(3,4-dimethoxyphenyl)-3-methylbutanenitrile; 2-(3,4-DiMethoxy phenyl)-d-Methylbutyronitrile; 2-(3,4-DIMETHOXY PHENYL)-SS-METHYLBUTYRONITRILE; (2RS)-2-(3,4-DIMETHOXYPHENYL)-3-METHYLBUTANENITRILE; 3-Methyl-2-(3,4-dimethoxyphenyl)butyronitrile; 3-METHYL-2-(3,4-DIMETHOXYPHENYL)BUTYRONITRILE; 2-(3,4-DiMethoxy phenyl)-ó-Methylbutyronitrile; 2-(3,4-Dimethoxy Pheny)-3-Methylbutyronitrile; 2-(3,4-Dimethoxyphenyl)-3-Methylbutaneni; 2-(3,4-DIMETHOXY PHENYL)-3-METHYLBUTYRONITRILE; alpha-Isopropylveratryl cyanide; Verapamil Impurity 11（Verapamil Impurity K）

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 327.3±37.0 °C at 760 mmHg
• 熔点: 46-49ºC
• 分子式: C₁₃H₁₇NO₂
• 分子量: 219.280
• 闪点: 114.5±19.7 °C
• 精确质量: 219.125931
• PSA: 42.25000
• LogP: 2.41
• 外观性状: 淡黄色固体
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.499
• 储存条件: -20°C Freezer

安全

• 海关编码: 2926909090

合成路线

93-17-4 75-26-3 ~82% 20850-49-1

文献：Wang, Cheng; Wang, Tao; Zhou, Nan; Pan, Xiao-Yan; He, Huai-Zhen Journal of Asian Natural Products Research, 2014 , vol. 16, # 3 p. 304 - 311

14046-55-0 105-39-5 ~81% 20850-49-1

文献：Alfa Chemicals Italiana S.r.l. Patent: EP285890 A2, 1988 ;

92040-70-5 109-70-6 ~70% 20850-49-1

文献：G. D. Searle and Co. Patent: US4681970 A1, 1987 ;

7677-24-9 67031-41-8 ~87% 20850-49-1

文献：Chen, Gang; Wang, Zheng; Wu, Jiang; Ding, Kuiling Organic Letters, 2008 , vol. 10, # 20 p. 4573 - 4576

102201-29-6 ~% 20850-49-1

文献：US4697035 A1, ;

上下游产品

上游产品  8
93-17-4 75-26-3 14046-55-0 105-39-5
109-70-6 7677-24-9 67031-41-8 102201-29-6
下游产品  6
34245-14-2 36622-28-3 27339-25-9 27487-83-8
102201-30-9 27487-66-7

海关

海关编码	2926909090
中文概述	2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%