1987-71-9

• 常用中文名：烟酰胺抗坏血酸盐
• 常用英文名：Nicotinamide ascorbate
• CAS号：1987-71-9
• 分子式：C₁₂H₁₄N₂O₇
• 分子量：298.24900
• 发布时间：2016-11-21 06:35:25
• 更新时间：2024-01-13 18:31:40
• Nicotinamide ascorbate is a bioactive chemical.

名称

• 中文名: 烟酰胺抗坏血酸盐
• 英文名: niacinamide ascorbate
• 英文别名: Nicotinsaeure-amid,Verbindung mit Isoascorbinsaeure; L-Ascorbate NicotinaMide; Nicotinamide/L-ascorbic acid; NicotinaMide L-Ascorbate; Nitubine; nicotinic acid amide,compound with isoascorbic acid; Nitubin; Merpress; NIACINAMIDEASCORBATE,FCC; Nicoscorbine

物化性质

• 沸点: 415.8ºC at 760mmHg
• 分子式: C₁₂H₁₄N₂O₇
• 分子量: 298.24900
• 闪点: 180.4ºC
• 精确质量: 298.08000
• PSA: 163.20000
• 蒸汽压: 1.18E-08mmHg at 25°C

MSDS

Section 1. Chemical Product and Company Identification Niacinamide ascorbate Common Name/ Trade Name Niacinamide ascorbate Section 3. Hazards Identification Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. Potential Acute Health Effects CARCINOGENIC EFFECTS: Not available. Potential Chronic Health MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast. [Ascorbic acid]. Mutagenic for bacteria and/or yeast. Effects [Niacinamide]. TERATOGENIC EFFECTS: Not available. DEVELOPMENTAL TOXICITY: Not available. Repeated or prolonged exposure is not known to aggravate medical condition. Section 4. First Aid Measures Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least Eye Contact 15 minutes. Cold water may be used. Get medical attention if irritation occurs. Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Skin Contact Cold water may be used. Not available. Serious Skin Contact If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get Inhalation medical attention. Not available. Serious Inhalation Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an Ingestion unconscious person. Loosen tight clothing such as a collar, tie, belt or waistband. Get medical attention if symptoms appear. Not available. Serious Ingestion Section 5. Fire and Explosion Data Flammability of the Product May be combustible at high temperature. Auto-Ignition Temperature The lowest known value is 660°C (1220°F) (Ascorbic acid). Not available. Flash Points Not available. Flammable Limits These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...). Products of Combustion Fire Hazards in Presence of Slightly flammable to flammable in presence of open flames and sparks, of heat. Non-flammable in presence of shocks. Various Substances Risks of explosion of the product in presence of mechanical impact: Not available. Explosion Hazards in Slightly explosive in presence of open flames and sparks. Presence of Various Substances SMALL FIRE: Use DRY chemical powder. Fire Fighting Media LARGE FIRE: Use water spray, fog or foam. Do not use water jet. and Instructions Material in powder form, capable of creating a dust explosion. As with most organic solids, fire is possible at elevated Special Remarks on temperatures Fire Hazards Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust Special Remarks on explosion hazard. Explosion Hazards Niacinamide ascorbate Section 6. Accidental Release Measures Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading Small Spill water on the contaminated surface and dispose of according to local and regional authority requirements. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on Large Spill the contaminated surface and allow to evacuate through the sanitary system. Section 7. Handling and Storage Keep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not Precautions ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the container or the label. Keep away from incompatibles such as oxidizing agents, metals, acids, alkalis. Keep container tightly closed. Keep container in a cool, well-ventilated area. Oxygen Sensitive Sensitive to light. Storage Store in light-resistant containers. Section 8. Exposure Controls/Personal Protection Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below Engineering Controls recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection Personal Protection in Case Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE of a Large Spill handling this product. Not available. Exposure Limits Section 9. Physical and Chemical Properties Solid. (Crystalline powde)Odorless. Physical state andO dor appearance Not available. Taste Not applicable. Molecular Weight Lemon Yellow. Color Not available. pH (1% soln/water) Not available. Boiling Point 141°C (285.8°F) - 145 C. Melting Point The lowest known value is 509.85°C (949.7°F) (Ascor bic acid). Critical Temperature Weighted average: 1.58 (Water = 1) Specific Gravity Not applicable. Vapor Pressure Not available. Vapor Density Not available. Volatility Not available. Odor Threshold The product is equally soluble in oil and water. Water/Oil Dist. Coeff. Not available. Ionicity (in Water) See solubility in water, diethyl ether, n-octanol. Dispersion Properties Niacinamide ascorbate Soluble in cold water, hot water, n-octanol. Solubility Slightly soluble in diethyl ether. Solubility in Water: 285000 mg/l water or 1 g/3.5 ml water. Solubility in Alcohol: 1 g/20 ml alcohol. Very slightly soluble in chloroform. Sparingly soluble in Glycerine. Virtually insoluble in Benzene. Section 10. Stability and Reactivity Data The product is stable. Stability Not available. Instability Temperature Conditions of Instability Excess heat, incompatible materials, air, oxygen, dust generation. Incompatibility with various Reactive with oxidizing agents, metals, acids, alkalis. substances Non-corrosive in presence of glass. Corrosivity Sensitive to light. Sensitive to Oxygen. Air sensitive. It may gradually darken upon exposure to air. Special Remarks on Reactivity Not available. Special Remarks on Corrosivity Will not occur. Polymerization Section 11. Toxicological Information Inhalation. Ingestion. Routes of Entry Acute oral toxicity (LD50): 2500 mg/kg [Rat]. Toxicity to Animals Chronic Effects on Humans MUTAGENIC EFFECTS: Mutagenic for bacteria and/or yeast. [Ascorbic acid]. Mutagenic for bacteria and/or yeast. [Niacinamide]. Other Toxic Effects onSlightly hazardous in case of skin contact (irritant), of ingestion, of inhalation. Humans Special Remarks onNot available. Toxicity to Animals May affect genetic material (mutagenic). Special Remarks on Chronic Effects on Humans May cause adverse reproductive effects and birth defects (teratogenic) based on animal test data. Human: passes through the placenta, excreted in maternal milk. (Ascorbic acid) Special Remarks on otherAcute Potential Health Effects: Skin: May cause skin irritation. Toxic Effects on Humans Eyes: May cause eye irritation. Inhalation: May cause respiratory tract irritation. Ingestion: Ingestion of small amounts during normal industrial handling is a low hazard. Ingestion of large amounts may cause gastrointestinal tract irritation, hypermotility, diarrhea, acidification of the urine which may cause stones in the urinary tract and may cause renal failure . May also affect behavior (psychomotor coordination, somnolence), eyes(lacrimation), blood (anemia). Chronic Potential Health Effects: Ingestion: Prolonged or repeated ingestion may affect the blood/bone marrow and cause weight loss Niacinamide ascorbate Section 12. Ecological Information Not available. Ecotoxicity Not available. BOD5 and COD Products of Biodegradation Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise. The product itself and its products of degradation are not toxic. Toxicity of the Products of Biodegradation Not available. Special Remarks on the Products of Biodegradation Section 13. Disposal Considerations Waste must be disposed of in accordance with federal, state and local environmental control Waste Disposal regulations. Section 14. Transport Information Not a DOT controlled material (United States). DO T Cl assi fi cati on Not applicable. Identification Not applicable. Special Provisions for Transport DO T (Pi ctograms) Section 15. Other Regulatory Information and Pictograms No products were found. Federal and State Regulations California prop. 65: This product contains the following ingredients for which the State of California has found to California cause cancer which would require a warning under the statute: No products were found. Proposition 65 Warnings California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. Other RegulationsFor CAS no. 1987-71-9: EINECS: This product is not on the European Inventory of Existing Commercial Chemical Substances. Canada: Not listed on Canadian Domestic Substance List (DSL) or Canadian Non- Domestic Substance List (NDSL). China: Not listed on National Inventory. Japan: Not listed on National Inventory (ENCS). Korea: Not listed on National Inventory (KECI). Philippines: Not listed on National Inventory (PICCS). Australia: Not listed on AICS. WHMIS (Canada) Not controlled under WHMIS (Canada). Other Classifications This product is not classified according Not applicable. DSCL (EEC) to the EU regulations. HMIS (U.S.A.)Health Hazard1 National Fire Protection 1 Flammability 1 Association (U.S.A.) Fire Hazard 1 0 Reactivity Health Reactivity0 Specific hazard Personal Protection E Niacinamide ascorbate WHMIS (Canada) (Pictograms) DSCL (Europe) (Pictograms) TDG(Canada) (Pictograms) ADR (Europe) (Pictograms) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Niacinamide ascorbate All chemicals may pose unknown hazards and should be used withcaution. This Material Safety Data Sheet (MSDS) applies only to the material as packaged. If this product is combined with other materials, deteriorates, or becomes contaminated, it may pose hazards not mentioned inthis MSDS. It shall be the user's responsibility to develop proper methods of handling and personal protection based onthe actual SECTION 16 - ADDITIONAL INFORMATION N/A