110548-07-7

• 常用中文名：(R)-氧氟沙星羧酸
• 常用英文名：(R)-(+)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
• CAS号：110548-07-7
• 分子式：C₁₃H₉F₂NO₄
• 分子量：281.21200
• 发布时间：2017-12-28 15:31:02
• 更新时间：2026-07-09 08:44:15

名称

• 中文名: (R)-氧氟沙星羧酸
• 英文名: (R)-(+)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid
• 中文别名: 左氧氟沙星杂质L; (R)-9,10-二氟-3-甲基-7-氧代-2,3-二氢-7H-[1,4]恶嗪并[2,3,4-IJ]喹啉-6-羧酸; 左氧氟沙星20
• 英文别名: Levofloxacin impurity 14/(R)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-cboxylic acid; Levofloacin Impurity L; (R)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-cboxylic acid; (R)-Ofloxacin Cboxylic Acid; (+)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid; Levofloxacin-12; .(+)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido(1,2,3-de)[1,4]benzoxazine-6-carboxylic acid; .(R)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid; 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-cboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, (3R); (R)-(+)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-cboxylic acid; .[R]-(+)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid; (3R)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-cboxylic Acid; .(+)-9,10-difluoro-3(R)-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid; .(+)-9,10-difluoro-3(R)-methyl-7-oxo-2,3-dihydro-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic acid

物化性质

• 分子式: C₁₃H₉F₂NO₄
• 分子量: 281.21200
• 精确质量: 281.05000
• PSA: 68.53000
• LogP: 1.93130

合成路线

110548-06-6 ~58% 110548-07-7

文献：Mitscher; Sharma; Chu; Shen; Pernet Journal of Medicinal Chemistry, 1987 ,  vol. 30,  # 12  p. 2283 - 2286

110548-05-5 ~65% 110548-07-7

文献：Mitscher; Sharma; Chu; Shen; Pernet Journal of Medicinal Chemistry, 1987 ,  vol. 30,  # 12  p. 2283 - 2286

103995-33-1 ~% 110548-07-7

文献：Mitscher; Sharma; Chu; Shen; Pernet Journal of Medicinal Chemistry, 1987 ,  vol. 30,  # 12  p. 2283 - 2286

110548-04-4 ~% 110548-07-7

文献：Mitscher; Sharma; Chu; Shen; Pernet Journal of Medicinal Chemistry, 1987 ,  vol. 30,  # 12  p. 2283 - 2286

上下游产品

上游产品  4
110548-06-6 110548-05-5 103995-33-1 110548-04-4
下游产品  1
100986-86-5