中文名 | 3,3'-二氨基联苯胺四盐酸盐 |
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英文名 | 3,3',4,4'-Biphenyltetramine tetrahydrochloride |
中文别名 |
3,3'-二氨基联苯氨四盐酸盐
3,3''-二氨基联苯胺四盐酸盐 3,3’-二氨基联苯胺,盐酸盐 |
英文别名 |
DAB TABLET
DAB SUBSTRATE DAB-HCL Biphenyl-3,3',4,4'-tetramine tetrahydrochloride DAB TETRAHYDROCHLORIDE DAB 3,3',4,4'-Biphenyltetramine tetrahydrochloride DAB,tetrahydrochloride3 3,3`-Diaminobenzidine tetrahydrochloride DAB EASY tablets DAB anhydrous MFCD00012969 [1,1'-Biphenyl]-3,3',4,4'-tetramine, hydrochloride (1:4) DAB 4HCL EINECS 231-018-9 DAB WITH METAL ENHANCER |
描述 | 3,3'-Diaminobenzidine(DAB)是有机化合物,具有化学和热力学稳定性,可用于核酸和蛋白的免疫组化染色。 |
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相关类别 | |
参考文献 |
[1]. Hannetz Roschzttardtz, et al. Plant Cell Nucleolus as a Hot Spot for Iron. |
沸点 | 481.7ºC at 760 mmHg |
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熔点 | 300°C |
分子式 | C12H18Cl4N4 |
分子量 | 360.110 |
闪点 | 282.7ºC |
精确质量 | 358.028564 |
PSA | 104.08000 |
LogP | 7.21520 |
外观性状 | 灰色至紫色-棕色粉末 |
储存条件 | 密封于2-8℃阴凉干燥环境。 |
稳定性 | 如果遵照规格使用和储存则不会分解。 |
水溶解性 | Soluble |
分子结构 | 1、摩尔折射率:无可用 2、 摩尔体积(cm3/mol): 无可用 3、 等张比容(90.2K):无可用 4、 表面张力(dyne/cm):无可用 5、 极化率:无可用 |
计算化学 | 1、 疏水参数计算参考值(XlogP):无可用 2、 氢键供体数量:8 3、 氢键受体数量:4 4、 可旋转化学键数量:1 5、 拓扑分子极性表面积(TPSA):104 6、 重原子数量:20 7、 表面电荷:0 8、 复杂度:209 9、 同位素原子数量:0 10、 确定原子立构中心数量:0 11、 不确定原子立构中心数量:0 12、 确定化学键立构中心数量:0 13、 不确定化学键立构中心数量:0 14、 共价键单元数量:5 |
更多 | 1. 性状:无可用 2. 密度(g/mL,25/4℃): 无可用 3. 相对蒸汽密度(g/mL,空气=1):无可用 4. 熔点(ºC):125 5. 沸点(ºC,常压):无可用 6. 沸点(ºC,5.2kPa): 无可用 7. 折射率: 无可用 8. 闪点(ºC): 无可用 9. 比旋光度(º):无可用 10. 自燃点或引燃温度(ºC):无可用 11. 蒸气压(kPa,25ºC):无可用 12. 饱和蒸气压(kPa,60ºC):无可用 13. 燃烧热(KJ/mol):无可用 14. 临界温度(ºC):无可用 15. 临界压力(KPa):无可用 16. 油水(辛醇/水)分配系数的对数值:无可用 17. 爆炸上限(%,V/V):无可用 18. 爆炸下限(%,V/V): 无可用 19. 溶解性:可溶于水 |
Synonym:3,3',4,4'-Biphenyltetramine tetrahydrochloride; 3,3',4,4'-Tetraaminobiphenyl tetrahydrochloride Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: 33 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Danger of cumulative effects. Irritating to eyes, respiratory system and skin.Cancer suspect agent. Potential Health Effects Eye: Causes eye irritation. May cause chemical conjunctivitis. Skin: Causes skin irritation. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Inhalation: Causes respiratory tract irritation. Can produce delayed pulmonary edema. Chronic: Effects may be delayed. Animal studies have reported the development of tumors. Potential cancer hazard. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep refrigerated. (Store below 4C/39F.) Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 7411-49-6: United States OSHA: (Cancer suspect agent - see 29 CFR 1910.1010) (listed under Benzidine). France - VME: (listed as benzidine): 0.001 ppm VME; 0.008 mg/m3 V Germany: (listed as benzidine): 0.001 ppm VME; 0.008 mg/m3 VME Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: off-white to gray Odor: none reported pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 280 deg C Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C12H14N4.4HCl.2H2O Molecular Weight: 396.14 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials, strong oxidants, strong oxidants. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 7411-49-6: DV8753000 LD50/LC50: Not available. Carcinogenicity: 3,3'-Diaminobenzidine tetrahydrochloride - California: carcinogen, initial date 2/27/87 (listed as Benzidine). NTP: Known carcinogen (listed as Benzidine). IARC: Group 1 carcinogen (listed as Benzidine). Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Shipping Name: Not regulated. Hazard Class: UN Number: Packing group: Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 33 Danger of cumulative effects. R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 22 Do not breathe dust. S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 7411-49-6: No information available. Canada CAS# 7411-49-6 is listed on Canada's DSL List. CAS# 7411-49-6 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 7411-49-6 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A |
毒理学数据: 1 。 2.肺 ,胸部或呼吸-肿瘤 2.肺,胸部或呼吸-肿瘤 生态学数据: 该物质对环境可能有危害,对水体应给予特别注意。 CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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符号 |
GHS07, GHS08 |
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信号词 | Danger |
危害声明 | H302-H319-H341-H350 |
警示性声明 | P201-P280-P301 + P312 + P330-P305 + P351 + P338-P308 + P313-P337 + P313 |
危害码 (欧洲) | Xn:Harmful; |
风险声明 (欧洲) | R22;R36/37/38;R40 |
安全声明 (欧洲) | S7-S16-S24-S33-S36/37-S45-S24/25-S22 |
危险品运输编码 | UN 3316 9/PG 2 |
WGK德国 | 3 |
RTECS号 | DV8753000 |
危险类别 | 9.0 |