16143-84-3

• 常用中文名：3,5-双(三氟甲基)乙酰苯胺
• 常用英文名：3,5-bis(trifluoromethyl)acetanilide
• CAS号：16143-84-3
• 分子式：C₁₀H₇F₆NO
• 分子量：271.15900
• 发布时间：2018-07-01 19:03:10
• 更新时间：2024-01-08 15:30:01

名称

• 中文名: 3,5-双(三氟甲基)乙酰苯胺
• 英文名: N-[3,5-bis(trifluoromethyl)phenyl]acetamide
• 中文别名: 3,5-二(三氟甲基)乙酰苯胺
• 英文别名: Essigsaeure-(3,5-bis-trifluormethyl-anilid); MFCD00089454; N-(3,5-bis(trifluoromethyl)phenyl)acetamide; 1-acetamido-3,5-bis(trifluoromethyl)benzene; 3,5-DiCF3 acetanilide; acetic acid-(3,5-bis-trifluoromethyl-anilide); GNF-Pf-1581

物化性质

• 密度: 1.43g/cm3
• 沸点: 262.6ºC at 760mmHg
• 熔点: 160 °C
• 分子式: C₁₀H₇F₆NO
• 分子量: 271.15900
• 闪点: 112.6ºC
• 精确质量: 271.04300
• PSA: 29.10000
• LogP: 3.75560
• 蒸汽压: 0.0108mmHg at 25°C
• 折射率: 1.445
• 分子结构:

  分子性质数据：

  1、 摩尔折射率：50.48

  2、 摩尔体积（m³/mol）：189.5

  3、 等张比容（90.2K）：425.4

  4、 表面张力（dyne/cm）：25.3

  5、 极化率（10^-24cm³）：20.01

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:7

  4.可旋转化学键数量:1

  5.互变异构体数量:3

  6.拓扑分子极性表面积29.1

  7.重原子数量:18

  8.表面电荷:0

  9.复杂度:289

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1.性状：未确定

  2.密度（g/mL,25/4℃）：未确定

  3.相对蒸汽密度（g/mL,空气=1）：未确定

  4.熔点（ºC）：160

  5.沸点（ºC,常压）：未确定

  6.沸点（ºC,5.2kPa）：未确定

  7.折射率：未确定

  8.闪点（ºC）：未确定

  9.比旋光度（º）：未确定

  10.自燃点或引燃温度（ºC）：未确定

  11.蒸气压（kPa,25ºC）：未确定

  12.饱和蒸气压（kPa,60ºC）：未确定

  13.燃烧热（KJ/mol）：未确定

  14.临界温度（ºC）：未确定

  15.临界压力（KPa）：未确定

  16.油水（辛醇/水）分配系数的对数值：未确定

  17.爆炸上限（%,V/V）：未确定

  18.爆炸下限（%,V/V）：未确定

  19.溶解性：未确定

MSDS

Name: N1-[3 5-di(trifluoromethyl)phenyl]acetamide 97% Material Safety Data Sheet Synonym: CAS: 16143-84-3 Section 1 - Chemical Product MSDS Name:N1-[3 5-di(trifluoromethyl)phenyl]acetamide 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 16143-84-3 N1-[3,5-Di(trifluoromethyl)phenyl]acet 97% unlisted Hazard Symbols: XN Risk Phrases: 22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: May cause respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 16143-84-3: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 160 - 162 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H7F6NO Molecular Weight: 271 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Acids, bases, oxidizing agents, reducing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, fluorine, hydrogen fluoride gas. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 16143-84-3 unlisted. LD50/LC50: Not available. Carcinogenicity: N1-[3,5-Di(trifluoromethyl)phenyl]acetamide - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 22 Harmful if swallowed. Safety Phrases: WGK (Water Danger/Protection) CAS# 16143-84-3: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 16143-84-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 16143-84-3 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S36/37/39
• 海关编码: 2924299090

合成路线

108-24-7 328-74-5 ~% 16143-84-3

文献：Journal of the American Chemical Society, , vol. 68, p. 1602,1603

328-74-5 ~96% 16143-84-3

文献：The State of Oregon, acting by and through The Oregon State Board of Higher Education, acting for and on behalf of The Oregon Health Sciences University; The University of Oregon; The Regents of the University of California Patent: US5514680 A1, 1996 ; US 5514680 A

141-78-6 328-74-5 ~95% 16143-84-3

文献：Tong, Xinli; Ren, Zhangshun; Que, Xiaolong; Yang, Qiwu; Zhang, Wenqin Research on Chemical Intermediates, 2012 , vol. 38, # 8 p. 1961 - 1968

328-75-6 ~% 16143-84-3

文献：Journal of the American Chemical Society, , vol. 68, p. 1602,1603

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%