2140-67-2

• 常用中文名：N2,N2-二甲基鸟苷
• 常用英文名：N2N2-Dimethylguanosine
• CAS号：2140-67-2
• 分子式：C₁₂H₁₇N₅O₅
• 分子量：311.294
• 相关类别： 生物化工 核苷类药物 核苷中间体
• 发布时间：2018-08-19 18:20:13
• 更新时间：2026-06-29 20:46:12
• N2,N2-Dimethylguanosine 是一种尿核苷,是 tRNA 的初级代谢产物。

名称

• 中文名: N2,N2-二甲基鸟苷
• 英文名: N2,N2-dimethylguanosine
• 中文别名: 9-((2R,3R,4S,5R)-3,4-二羟基-5-(羟甲基)四氢呋喃-2-基)-2-(二甲氨基)-1,9-二氢-6H-嘌呤-6-酮; N,N-二甲基鸟苷; 2-(二甲基氨基)鸟苷; N,N-二甲基鸟嘌呤核苷; 2-二甲氨基鸟苷; N2-二甲基鸟苷; N2,N2-二甲基鸟苷,10 MM DMSO 溶液
• 英文别名: 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methylol-tetrahydrofuran-2-yl]-2-(dimethylamino)-3H-purin-6-one; 2-Dimethylamino-D-guanosine; N,N-dimethyl-Guanosine; N-2,N2-Dimethylguanosine,N2,N2-Dimethylguanosine,inhibit,Inhibitor,N2,N2Dimethylguanosine,Endogenous Metabolite,N2,N2 Dimethylguanosine; 2,2-DiMethylguanosine; N2,N2-Dimethyl-guanosin; N2,N2-DIMETHYLGUANOSINE; 2-(DIMETHYLAMINO)GUANOSINE //BP; N,N- dimethylguanosine; N,N-Dimethylguanosine; 9-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2-(dimethylamino)-3,9-dihydro-6H-purin-6-one; GUANOSINE,N,N-DIMETHYL; 2-(DIMETHYLAMINO)GUANOSINE; 2-(DIMETHYLAMINO)GUA; N2,N2-Dimethylguanosine, 10 mM in DMSO; 2-N,2-N-dimethylguanosine; N(sup 2),N(sup 2)-dimethylguanosine; N2-Dimethylguanosine; M(2/2) GUO; RNA-modified nucleoside m; N(2),N(2)-Dimethylguanosine; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-dimethylamino-1H-purin-6-one; 2-DiMethylaMino-6-oxypurine Riboside; 9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-(dimethylamino)-3H-purin-6-one

物化性质

• 密度: 1.8±0.1 g/cm3
• 沸点: 683.6ºC at 760 mmHg
• 熔点: 235-236ºC
• 分子式: C₁₂H₁₇N₅O₅
• 分子量: 311.294
• 闪点: 367.2ºC
• 精确质量: 311.122955
• PSA: 136.73000
• LogP: -3.12
• 外观性状: 白色固体
• 蒸汽压: 1.27E-19mmHg at 25°C
• 折射率: 1.786
• 储存条件: 2-8°C

生物活性

• 描述: N2,N2-Dimethylguanosine 是一种尿核苷,是 tRNA 的初级代谢产物。
• 相关类别:
  研究领域 >> 癌症
  天然产物 >> 其他
• 靶点:

  Human Endogenous Metabolite

• 参考文献:

  [1]. Zheng YF, et al. Urinary nucleosides as biological markers for patients with colorectal cancer. World J Gastroenterol. 2005 Jul 7;11(25):3871-6.

安全

• WGK德国: 3
• 海关编码: 2934999090

合成路线

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%