119770-60-4

• 常用中文名：(1-甲基-4-哌啶基)[3-[2-(3-氯苯基)乙基]吡啶-2-基]甲酮盐酸盐
• 常用英文名：(3-(3-CHLOROPHENETHYL)PYRIDIN-2-YL)(1-METHYLPIPERIDIN-4-YL)METHANONE HYDROCHLORIDE
• CAS号：119770-60-4
• 分子式：C₂₀H₂₄Cl₂N₂O
• 分子量：379.323
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 乙基吡啶
• 发布时间：2018-12-11 15:27:12
• 更新时间：2026-07-14 07:53:02

名称

• 中文名: (1-甲基-4-哌啶基)[3-[2-(3-氯苯基)乙基]吡啶-2-基]甲酮盐酸盐
• 英文名: (1-Methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridinyl]methanone hydrochloride
• 中文别名: 氯雷他定杂质10盐酸盐; 地氯雷他定杂质20; 氯雷他定杂质39 盐酸盐; 氯雷他定杂质10; 氯雷他定杂质36 盐酸盐; 氯雷他定甲酮杂质; 3-[2-(3-氯苯基)乙基]-2-吡啶基](1-甲基-4-哌啶基)盐酸甲酮; 氯雷他定杂质10 HCL; 氯雷他定甲酮盐酸盐; 氯雷他定甲甲酮; (3-(3-氯苯乙基)吡啶-2-基)(1-甲基哌啶-4-基)甲酮盐酸盐
• 英文别名: Des Loratadine methanone; (1-methyl-4-piperidinyl)<3-<2-(3-chlorophenyl)ethyl>-2-pyridinyl>methanone hydrochloride; Desloratadine Impurity 3/Desloratadine Methanone Impurity HCl/Desloratadine Ketone Impurity HCl; {3-[2-(3-Chlorophenyl)ethyl]pyridine-2-yl}-(1-methylpiperidine-4-yl) (Methonal HCL); DESLORATADINE METHANONE IMPURITY (HCL SALT); (1-methyl-4-piperidinyl) [3- [2- (3-chlorophenyl) ethyl] pyridin-2-yl] ketone hydrochloride; Loratadine Impurity ((1-Methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridinyl]methanone); (3-(3-chlorophenethyl)pyridin; {3-[2-(3-chlorophenyl)ethyl]pyridin-2-yl}(4- methylcyclohexyl)methanone; Methanone, [3-[2-(3-chlorophenyl)ethyl]-2-pyridinyl](1-methyl-4-piperidinyl)-, hydrochloride (1:1); Desloratadine Methanone Impurity/ Desloratadine Ketone Impurity (Loratadine Methanone Impurity); [3-[2-(3-Chlorophenyl)ethyl]-2-pyridinyl](1-methyl-4-piperidinyl)methanone hydrochloride; Loratadine Methanone Impurity (Desloratadine Methanone Impurity/ Desloratadine Ketone Impurity); Loratadine Impurity 10; Loratadine Impurity 39 HCl; Loratadine Methyl Ketone; DesloratadineMethanoneImpurityHCl; (3-(3-Chlorophenethyl)pyridin-2-yl)(1-methyl-piperidin-4-yl)methanone hydrochloride; Loratadine Impurity 36 HCl; (1-Methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridiny; [3-[2-(3-chlorophenyl)ethyl]pyridin-2-yl]-(1-methylpiperidin-4-yl)methanone:hydrochloride; (1-Methyl-4-piperidinyl)[3-[2-(3-chlorophenyl)ethyl]pyridinyl]methanone hydrochloride ISO 9001：2015 REACH; Loratadine Impurity 10 HCl; Desloratadine Methanone Impurity; {3-[2-(3-Chlorophenyl)ethyl]pyridin-2-yl}(1-methylpiperidin-4-yl)methanone hydrochloride (1:1); Loratadine Methanone Impurity; {3-[2-(3-Chlorophenyl)ethyl]-2-pyridinyl}(1-methyl-4-piperidinyl)methanone hydrochloride (1:1)

物化性质

• 熔点: 183-185ºC
• 分子式: C₂₀H₂₄Cl₂N₂O
• 分子量: 379.323
• 精确质量: 378.126556
• PSA: 33.20000
• LogP: 4.78460

安全

• 海关编码: 2933990090

合成路线

20970-75-6 ~% 119770-60-4

文献：Journal of Organic Chemistry, , vol. 54, # 9 p. 2242 - 2244

32998-95-1 ~% 119770-60-4

文献：Journal of Organic Chemistry, , vol. 54, # 9 p. 2242 - 2244

31255-57-9 ~% 119770-60-4

文献：Journal of Organic Chemistry, , vol. 54, # 9 p. 2242 - 2244

107285-30-3 ~% 119770-60-4

文献：Journal of Organic Chemistry, , vol. 54, # 9 p. 2242 - 2244

63463-36-5 ~% 119770-60-4

文献：Journal of Organic Chemistry, , vol. 54, # 9 p. 2242 - 2244

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%