31255-57-9

• 常用中文名：3-[2-(3-氯苯基)乙基]-2-吡啶甲腈
• 常用英文名：Loratadine Impurity 18
• CAS号：31255-57-9
• 分子式：C₁₄H₁₁ClN₂
• 分子量：242.70400
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 乙基吡啶
• 发布时间：2018-12-31 17:22:24
• 更新时间：2026-07-11 01:13:41

名称

• 中文名: 3-[2-(3-氯苯基)乙基]-2-吡啶甲腈
• 英文名: 2-Cyano-3-(3-chlorophenylethyl)pyridine
• 中文别名: 氯雷他定起始物料; 3-(3-氯苯乙基)吡啶甲腈; 3-[2-(3-氯苯基)乙基]-2-吡啶甲腈 氯雷他定中间体; 氯雷他定氰基杂质; 氯雷他定中间体3-[2-(3-氯苯基)乙基]-2-吡啶甲腈; 3-(3-氯苯基乙基)吡啶-2-甲腈
• 英文别名: 3(2-(3-CHLORO PHENYL)ETHYL) CYANO PYRIDINE (LORANITRILE); 2-cyano-3-[2-(3-chlorophenyl)ethyl]pyridine (M5); Loratadine Stting Material; 2-Cyano-3(3-chlorophenethyl)pyridine; 3- [2- (3-chlorophenyl) ethyl] -2-pyridine acetonitrile; 3-[2-(3-ChIorophenyI)ethyI]-2-pyridinecbonitriIe; Loratadine Cyano IMpurity; MFCD02942420; 3-[2-(3-Chlorophenyl)ethyl]-2-pyridine carbonitrile salicylic acid 13C6; 3-[2-(3-CHLOROPHENYL)-ETHYL]-PYRIDINE-2-carbonitrile; 3-[2-(3Chlorophenyl) ethyl)-2-cyano pyridine (or) 3-[2-(3-Chlorophenyl)–ethyl]–2–pyridine carbonitrile (Cyano compound); 3-(M-Chlorophenethyl)picolinonitrile; Lora-V; 2-Pyridinecbonitrile, 3-[2-(3-chlorophenyl)ethyl]; 3-[2-(3-CHLOROPHENYL)ETHYL]-2-CYANOPYRIDINE; 3-(3-Chlorophenethyl)picolinonitrile; 3-(2-(3-CHLORO PHENYL)ETHYL)-2-PYRIDINE carbonitrile; 3-[2-(3-Chlorophenyl)ethyl]-2-pyridinecbonitrile ISO 9001：2015 REACH; 3-K2-(3-CHLOROPHENYLJETHYLL-PYRIDINE carbonitrile; 3-[2-(3-chlorophenyl) ethyl] pyridine-2-carbonitrile / 2-Cyano-3-(3-chlorophenylethyl)pyridine; 3-[2-(3-Chlorophenyl)ethyl]-2-pyridinecarbonitrile; 3[2(3-chloro ohenyl)ethyl]2-cyano pyridine; 3-[2-(3-CHLOROBENZENE)ETHYL]-PYRIDINITRILE; 2-Cyano-3-[2(3-ChloroPhenyl)ethyl]pyridine(L-5); 3-[2-(3-CHLOROPHENYL)-ETHYL]-PYRIDINE carbonitrile

物化性质

• 密度: 1.23 g/cm3
• 沸点: 375.7ºC at 760 mmHg
• 熔点: 71-72ºC
• 分子式: C₁₄H₁₁ClN₂
• 分子量: 242.70400
• 闪点: 181ºC
• 精确质量: 242.06100
• PSA: 36.68000
• LogP: 3.39188
• 外观性状: 淡棕色固体
• 折射率: 1.605
• 储存条件: Refrigerator

安全

• 海关编码: 2933399090

合成路线

31255-47-7 143-33-9 ~73% 31255-57-9

文献：MOREPEN LABORATORIES LIMITED Patent: WO2006/6184 A2, 2006 ; Location in patent: Page/Page column 14 ;

107285-30-3 ~74% 31255-57-9

文献：Karcher, Solveigh C.; Laufer, Stefan A. Journal of Medicinal Chemistry, 2009 , vol. 52, # 6 p. 1778 - 1782

32998-95-1 ~% 31255-57-9

文献：Journal of Organic Chemistry, , vol. 54, # 9 p. 2242 - 2244

620-20-2 ~% 31255-57-9

文献：Journal of Medicinal Chemistry, , vol. 34, # 1 p. 457 - 461

20970-75-6 ~% 31255-57-9

文献：Journal of Organic Chemistry, , vol. 54, # 9 p. 2242 - 2244

上下游产品

上游产品  6
31255-47-7 143-33-9 107285-30-3 32998-95-1
620-20-2 20970-75-6
下游产品  7
31251-41-9 38092-89-6 79794-75-5 100643-71-8
119770-60-4 130642-50-1 117796-52-8

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%