974-41-4

• 常用中文名：8-苄基-1,3,8-三氮杂螺[4.5]癸烷-4-酮
• 常用英文名：8-Benzyl-1,3,8-triazaspiro[4.5]decane-4-one
• CAS号：974-41-4
• 分子式：C₁₄H₁₉N₃O
• 分子量：245.320
• 发布时间：2018-10-18 12:51:13
• 更新时间：2024-01-16 08:57:19

名称

• 中文名: 8-苄基-1,3,8-三氮杂螺[4.5]癸烷-4-酮
• 英文名: 8-benzyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
• 中文别名: 8-苄基-1-苯基-1,3,8-三氮杂螺[4.5]-4-癸酮
• 英文别名: 8-benzyl-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one; 1,3,8-Triazaspiro[4.5]decan-4-one, 8-(phenylmethyl)-; 8-Benzyl-1-oxo-4-phenyl-2,4,8-triazaspiro<4.5>decan; 8-Benzyl-1,3,8-triazaspiro[4.5]decan-4-one; 8-Benzyl-1,3,8-triazaspiro[4.5]decane-4-one

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 451.4±45.0 °C at 760 mmHg
• 熔点: 232-238ºC
• 分子式: C₁₄H₁₉N₃O
• 分子量: 245.320
• 闪点: 226.8±28.7 °C
• 精确质量: 245.152817
• PSA: 35.58000
• LogP: 0.09
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.616
• 储存条件: 室温

MSDS

Name: 8-Benzyl-4-oxo-phenyl-1 3 8-triazaspiro[4 5]decane 99% Material Safety Data Sheet Synonym: CAS: 974-41-4 Section 1 - Chemical Product MSDS Name:8-Benzyl-4-oxo-phenyl-1 3 8-triazaspiro[4 5]decane 99% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 974-41-4 8-Benzyl-4-oxo-phenyl-1,3,8-triazaspir 99% 213-549-8 Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Not available. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 974-41-4: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Crystalline powder Color: light yellow Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 538 deg C @760mmHg Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: 279 deg C ( 534.20 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: slightly soluble Specific Gravity/Density: Molecular Formula: C20H23N3O Molecular Weight: 321.42 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, acids, bases. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 974-41-4 unlisted. LD50/LC50: Not available. Carcinogenicity: 8-Benzyl-4-oxo-phenyl-1,3,8-triazaspiro[4, 5]decane - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 974-41-4: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 974-41-4 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 974-41-4 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

1096-03-3 77287-34-4 ~% 974-41-4

文献：Journal of Medicinal Chemistry, , vol. 51, # 2 p. 238 - 250

100-52-7 1021-25-6 ~% 974-41-4

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 2 p. 349 - 353

上下游产品

上游产品  4
1096-03-3 77287-34-4 100-52-7 1021-25-6
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%