429659-01-8

• 常用中文名：3-(4-(甲基氨基)-3-硝基-N-(吡啶-2-基)苯甲酰氨基)丙酸乙酯
• 常用英文名：Ethyl 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl)benzamido)propanoate
• CAS号：429659-01-8
• 分子式：C₁₉H₂₂N₄O₅
• 分子量：386.402
• 发布时间：2018-07-25 20:30:22
• 更新时间：2026-07-09 15:12:19

名称

• 中文名: 3-(4-(甲基氨基)-3-硝基-N-(吡啶-2-基)苯甲酰氨基)丙酸乙酯
• 英文名: Ethyl 3-(4-(ethylamino)-3-nitro-N-(pyridin-2-yl)benzamido)propanoate
• 中文别名: 3-(4-(甲基氨基)-3-硝基-N; 3-(4-(甲基氨基)-3-硝基-N-(吡啶-2-基)苯甲酰氨基)丙酸乙酯 (达比加群酯中间体); 3-(4-(甲基氨基)-3-硝基-N-(吡啶-2-基)苯甲酰胺基)丙酸乙酯; N-[4-甲胺基-3-硝基苯酰基]N-2-吡啶基- -丙氨酸乙酯; 达比加群杂质67; 达比加群酯杂质; 3-(4-(甲基氨基)-3-硝基-N-(吡啶-2-基)苯甲酰氨基)丙酸乙酯 (DG06); 达比加群酯杂质88; 达比加群酯杂质63; 3-(4-(甲基氨基)-3-硝基-N-(吡啶-2-基)苯甲酰氨基)丙酸乙酯(达比加群); 达比加群酯中间体N-4
• 英文别名: Ethyl 3-[(3-Nitro-4- methylaminobenzoyl)pyridin-2- ylamino]propionate; b-Alanine,N-[4-(MethylaMino)-3-nitrobenzoyl]-N-2-pyridinyl-, ethyl ester; Ethyl 3-(4-(methylamino)-3-nitro-N-(pyridine-2-yl) benzamido) propanoate; Ethyl 3-[[4-(Methylamino)-3-nitrobenzoyl]-(2-pyridyl)amino]propanoate; Ethyl 3-(4-(ethylaMino)-3-nitro-N-(pyridin-2-yl)benzaMido)propanoate; Ethyl 3-[3-Nitro-4-(methylamine)-N-(2-pyridyl) benzamido] propanoate; Ethyl 3-[(4-Methylamino-3-Nitro-Benzoyl)-Pyridin-2-Yl-Amin; Ethyl N-[4-(ethylamino)-3-nitrobenzoyl]-N-pyridin-2-yl-β-alaninate; Ethyl 3- (4- (methylamino) -3-nitro-N - (pyridin-2-yl) benzamido) propionate; Dabigatran Etexilate Impurity; ethyl 3-(4-(methylamino)-3-nitro-N-(pyridin-2-yl) benzamido)propanoate (DBI Nitro); ETHYL N-[4-(METHYLAMINO)-3-NITROBENZOYL]-N-PYRIDIN-2-YL-SS-ALANINATE; Ethyl N-[4-(ethylamino)-3-nitrobenzoyl]-N-2-pyridinyl-β-alaninate; Ethyl 3-[(4-Methylamino-3-nitro-benzoyl)-pyridin-2-yl-amino]-propionate; N-[4-(methylamino)-3-nitrobenzoyl]-N-2-pyridinyl-alanine eth; β-Alanine, N-[4-(MethylaMino)-3-nitrobenzoyl]-N-2-pyridinyl-, ethyl ester; Ethyl 3-[[4-(MethylaMino)-3-nitrobenzoyl](pyridin-2-yl)amino]propanoate; N-[4-methylamino)-3-nitrobenzoyl]-N-2-pyrinidyl-alanine ethyl ester; Dabigatran Impurity; Dabigatran Etexilate Impurity 88; β-Alanine, N-[4-(ethylamino)-3-nitrobenzoyl]-N-2-pyridinyl-, ethyl ester; ethyl 3-{1-[4-(MethylaMino)-3-nitrophenyl]-N-(pyridin-2-yl)forMaMido}propanoate; N-[4-(MethylaMino)-3-nitrobenzoyl]-N-2-pyridinyl-alanine ethyl ester; 3-(4-Methylamino)-3-nitro-N-(pyridin-2-yl)benzamidopropionate; 3-[(4-methylamino-3-nitro-benzoyl)pyridin-2-yl-amino]propionic acid ethyl ester; ETHYL-3-(4-(METHYL AMINO)-3-NITRO-N-(PYR IDIN-2-YL)BENZAMIDO)PROPANONATE; N-[4-(MethylaMino)-3-nitrobenzoyl]-N-2-pyridinyl-, ethyl ester Alanine; N-[4-(Methylamino)-3-nitrobenzoyl]-N-2-pyridinyl-β-alanine ethyl ester

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 590.6±50.0 °C at 760 mmHg
• 分子式: C₁₉H₂₂N₄O₅
• 分子量: 386.402
• 闪点: 311.0±30.1 °C
• 精确质量: 386.159027
• PSA: 117.35000
• LogP: 3.17
• 外观性状: NA
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.622
• 储存条件: 室温，干燥

安全

• 海关编码: 2933399090

合成路线

41263-74-5 ~% 429659-01-8

文献：Hauel, Norbert H.; Nar, Herbert; Priepke, Henning; Ries, Uwe; Stassen, Jean-Marie; Wienen, Wolfgang Journal of Medicinal Chemistry, 2002 , vol. 45, # 9 p. 1757 - 1766

96-99-1 ~% 429659-01-8

文献：CADILA HEALTHCARE LIMITED; DWIVEDI, Shriprakash Dhar; SINGH, Ramesh Chandra; RAVAL, Jigar Mukundbhai Patent: WO2013/111163 A2, 2013 ;

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海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%