61337-88-0

• 常用中文名：1-(3-氰基吡啶-2)-2-苯基-4-甲基哌嗪
• 常用英文名：1-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
• CAS号：61337-88-0
• 分子式：C₁₇H₁₈N₄
• 分子量：278.35200
• 发布时间：2018-12-17 13:36:06
• 更新时间：2025-08-27 11:14:32

名称

• 中文名: 1-(3-氰基吡啶-2)-2-苯基-4-甲基哌嗪
• 英文名: 1-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
• 中文别名: 米氮平甲腈杂质; 米氮氰; 米氮平氰基杂质; 2-(4-甲基-2-苯基-1-哌嗪基)烟腈; 米氮平腈杂质; 米氮平碳腈杂质; 米氮平杂质14; 米氮平含氰基的杂质; 2-(4-甲基-2-苯基哌嗪-1-基)烟腈
• 英文别名: Mirtazapine Impurity 8; 3-cyano-2-(4-methyl-2-phenyl-1-piperazynyl)pyridine; Mirtazapine Cyano Impurity/1-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine; 2-(4-Methyl-2-phenyl-1-piperazinyl)nicotinonitrile; Mirtazapine carbonitrile IMpurity; (3-Cyanopyridyl-2)-2-phenyl-4-methylpyperazine; 2-(4-Methyl-2-phenylpiperazin-1-yl)pyridine-3-carbonitrile; 2-(4-methyl-2-phenylpiperazin-1-yl)pyridine-3-carbonitrile; 1-(3-Cyanopyridyl-2)-2-Phenyl-4-Methylpyperazine; Mirtazapine Cyano Impurity; 3-Pyridinecbonitrile, 2-(4-methyl-2-phenyl-1-piperazinyl); 1-(3-Cyano-2-pyridyl)-4-Methyl-2-phenylpiperazine; 2-(4-Methyl-2-phenylpiperazin-1-yl)-3-cyanopyridine

物化性质

• 分子式: C₁₇H₁₈N₄
• 分子量: 278.35200
• 精确质量: 278.15300
• PSA: 43.16000
• LogP: 2.44928

安全

• 海关编码: 2933599090

合成路线

6602-54-6 5271-27-2 ~96% 61337-88-0

文献：Srinivasa Rao; Dandala; Handa; Sivakumaran; Raghava Reddyt; Naidu Organic Preparations and Procedures International, 2007 , vol. 39, # 4 p. 399 - 402

6602-54-6 821-55-6 5271-27-2 ~% 61337-88-0

文献：Akzona Incorporated Patent: US4062848 A1, 1977 ;

6602-54-6 5271-27-2 ~% 61338-13-4 61337-88-0

文献：Sebastian, Sonny; Patel, Hetal Virendra; Thennati, Rajamannar Patent: US2002/95038 A1, 2002 ;

6602-54-6 5271-27-2 ~86% 1174064-73-3 61337-88-0

文献：Lamazzi, Christelle; Dreau, Armelle; Bufferne, Christel; Flouzat, Christine; Carlier, Patrick; ter Halle, Rob; Besson, Thierry Tetrahedron Letters, 2009 , vol. 50, # 31 p. 4502 - 4505

6602-54-6 1072159-75-1 ~63% 1174064-76-6 5271-29-4 详细

文献：Lamazzi, Christelle; Dreau, Armelle; Bufferne, Christel; Flouzat, Christine; Carlier, Patrick; ter Halle, Rob; Besson, Thierry Tetrahedron Letters, 2009 , vol. 50, # 31 p. 4502 - 4505

6602-54-6 1072159-75-1 ~56% 333738-24-2 1174064-76-6 详细

文献：Lamazzi, Christelle; Dreau, Armelle; Bufferne, Christel; Flouzat, Christine; Carlier, Patrick; ter Halle, Rob; Besson, Thierry Tetrahedron Letters, 2009 , vol. 50, # 31 p. 4502 - 4505

6602-54-6 5271-27-2 ~36% 333738-24-2 1174064-76-6 详细

文献：Lamazzi, Christelle; Dreau, Armelle; Bufferne, Christel; Flouzat, Christine; Carlier, Patrick; ter Halle, Rob; Besson, Thierry Tetrahedron Letters, 2009 , vol. 50, # 31 p. 4502 - 4505

上下游产品

上游产品  4
6602-54-6 5271-27-2 821-55-6 1072159-75-1
下游产品  3
61338-13-4 61337-89-1 85650-52-8

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%