444620-69-3

• 常用中文名：4-(异喹啉-5-基)哌嗪-1-羧酸叔丁酯
• 常用英文名：TERT-BUTYL 4-(ISOQUINOLIN-5-YL)PIPERAZINE-1-CARBOXYLATE
• CAS号：444620-69-3
• 分子式：C₁₈H₂₃N₃O₂
• 分子量：313.39400
• 发布时间：2018-12-05 18:33:17
• 更新时间：2025-09-07 19:25:11

名称

• 中文名: 4-(5-异喹啉)-1-哌嗪羧酸 1,1-二甲基乙酯
• 英文名: tert-butyl 4-isoquinolin-5-ylpiperazine-1-carboxylate
• 英文别名: 4-Isoquinoline-5-yl-piperazine-1-carboxylic acid tert-butyl ester; tert-butyl 4-(isoquinolin-5-yl)piperazine-1-carboxylate; I14-8529

物化性质

• 密度: 1.172 g/cm3
• 沸点: 476.2ºC at 760 mmHg
• 分子式: C₁₈H₂₃N₃O₂
• 分子量: 313.39400
• 闪点: 241.8ºC
• 精确质量: 313.17900
• PSA: 45.67000
• LogP: 3.29480
• 折射率: 1.594
• 储存条件: 2-8°C，密封，干燥

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

34784-04-8 57260-71-6 ~69% 444620-69-3

文献：Kling, Andreas; Lange, Udo E. W.; Mack, Helmut; Bakker, Margot H. M.; Drescher, Karla U.; Hornberger, Wilfried; Hutchins, Charles W.; Moeller, Achim; Mueller, Reinhold; Schmidt, Martin; Unger, Liliane; Wicke, Karsten; Schellhaas, Kurt; Steiner, Gerd Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 24 p. 5567 - 5573

24424-99-5 209733-17-5 ~% 444620-69-3

文献：BRISTOL-MYERS SQUIBB COMPANY; ORWAT, Michael J.; PINTO, Donald J.P.; SMITH II, Leon M.; SRIVASTAVA, Shefali Patent: WO2013/56060 A1, 2013 ; Location in patent: Paragraph 00269 ;

119-65-3 ~% 444620-69-3

文献：Kling, Andreas; Lange, Udo E. W.; Mack, Helmut; Bakker, Margot H. M.; Drescher, Karla U.; Hornberger, Wilfried; Hutchins, Charles W.; Moeller, Achim; Mueller, Reinhold; Schmidt, Martin; Unger, Liliane; Wicke, Karsten; Schellhaas, Kurt; Steiner, Gerd Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 24 p. 5567 - 5573

34784-04-8 ~% 444620-69-3

文献：Fisher, Matthew J.; Backer, Ryan T.; Husain, Saba; Hsiung, Hansen M.; Mullaney, Jeffrey T.; O'Brian, Thomas P.; Ornstein, Paul L.; Rothhaar, Roger R.; Zgombick, John M.; Briner, Karin Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4459 - 4462

105685-17-4 24424-99-5 ~% 444620-69-3

文献：Fisher, Matthew J.; Backer, Ryan T.; Husain, Saba; Hsiung, Hansen M.; Mullaney, Jeffrey T.; O'Brian, Thomas P.; Ornstein, Paul L.; Rothhaar, Roger R.; Zgombick, John M.; Briner, Karin Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4459 - 4462

上下游产品

上游产品  6
34784-04-8 57260-71-6 24424-99-5 209733-17-5
119-65-3 105685-17-4
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%