59333-90-3

• 常用中文名：EXAPROLOL HYDROCHLORIDE
• 常用英文名：EXAPROLOL HYDROCHLORIDE
• CAS号：59333-90-3
• 分子式：C₁₈H₃₀ClNO₂
• 分子量：327.88900
• 发布时间：2016-04-30 10:29:30
• 更新时间：2024-09-03 12:27:11

名称

• 英文名: 1-(2-cyclohexylphenoxy)-3-(propan-2-ylamino)propan-2-ol,hydrochloride
• 英文别名: VULM 111 hydrochloride; Exaprolol hydrochloride; UNII-FGT82HNC7L; M.G. 8823; Exaprolol HCl

物化性质

• 分子式: C₁₈H₃₀ClNO₂
• 分子量: 327.88900
• 精确质量: 327.19700
• PSA: 41.49000
• LogP: 4.66490

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UA9813000 CHEMICAL NAME : 2-Propanol, 1-(2-cyclohexylphenoxy)-3-((1-methylethyl)amino)-, hydrochloride CAS REGISTRY NUMBER : 59333-90-3 LAST UPDATED : 198906 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C18-H29-N-O2.Cl-H MOLECULAR WEIGHT : 327.94 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1850 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 54 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 860 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 78 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,506,1976