20481-33-8

• 常用中文名：2-{[(1,3-二甲基-1H-吡唑-5-基)氨基]亚甲基}丙二酸二乙酯
• 常用英文名：DIETHYL 2-[[(1,3-DIMETHYL-1H-PYRAZOL-5-YL)AMINO]METHYLIDENE]MALONATE
• CAS号：20481-33-8
• 分子式：C₁₃H₁₉N₃O₄
• 分子量：281.30800
• 发布时间：2018-12-28 22:07:14
• 更新时间：2024-01-12 19:51:19

名称

• 中文名: 2-{[(1,3-二甲基-1H-吡唑-5-基)氨基]亚甲基}丙二酸二乙酯
• 英文名: diethyl 2-[[(2,5-dimethylpyrazol-3-yl)amino]methylidene]propanedioate
• 英文别名: diethyl 2-{[(1,3-dimethyl-1H-pyrazol-5-yl)amino]methylene}malonate; diethyl {[(1,3-dimethyl-1H-pyrazol-5-yl)amino]methylidene}propanedioate; diethyl 2-{[(1,3-dimethyl-1H-pyrazol-5-yl)amino]methylidene}malonate; diethyl {[(1,3-dimethyl-1H-pyrazol-5-yl)amino]methylene}malonate

物化性质

• 密度: 1.18g/cm3
• 沸点: 366.7ºC at 760mmHg
• 熔点: 85ºC
• 分子式: C₁₃H₁₉N₃O₄
• 分子量: 281.30800
• 闪点: 175.6ºC
• 精确质量: 281.13800
• PSA: 82.45000
• LogP: 1.22350
• 蒸汽压: 1.43E-05mmHg at 25°C
• 折射率: 1.532

MSDS

Name: Diethyl 2-{[(1 3-dimethyl-1h-pyrazol-5-yl)amino]methylidene}malonate Material Safety Data Sheet Synonym: Ethyl 3-(1,3-dimethylpyrazol-5-ylamino)-2-ethoxycarbonyl acrylat CAS: 20481-33-8 Section 1 - Chemical Product MSDS Name:Diethyl 2-{[(1 3-dimethyl-1h-pyrazol-5-yl)amino]methylidene}malonate Material Safety Data Sheet Synonym:Ethyl 3-(1,3-dimethylpyrazol-5-ylamino)-2-ethoxycarbonyl acrylat Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 20481-33-8 Diethyl 2-{[(1,3-dimethyl-1H-pyrazol-5 97% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 20481-33-8: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: cream Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 85 - 88 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C13H19N3O4 Molecular Weight: 281 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Reducing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 20481-33-8 unlisted. LD50/LC50: Not available. Carcinogenicity: Diethyl 2-{[(1,3-dimethyl-1H-pyrazol-5-yl)amino]methylidene}malonate - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 37/39 Wear suitable gloves and eye/face protection. WGK (Water Danger/Protection) CAS# 20481-33-8: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 20481-33-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 20481-33-8 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi:Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S37/39
• 海关编码: 2933199090

合成路线

3524-32-1 87-13-8 ~89% 20481-33-8

文献：Ochiai, Hiroshi; Ishida, Akiharu; Ohtani, Tazumi; Kusumi, Kensuke; Kishikawa, Katuya; Yamamoto, Susumu; Takeda, Hiroshi; Obata, Takaaki; Nakai, Hisao; Toda, Masaaki Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 15 p. 4089 - 4100

上下游产品

上游产品  2
3524-32-1 87-13-8
下游产品  3
175201-95-3 20481-15-6 175201-94-2

海关

海关编码	2933199090
中文概述	2933199090. 其他结构上有非稠合吡唑环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%