毒理学数据:
1 。
试验方法：口服
摄入剂量： 4920毫克/千克
测试对象：啮齿动物-鼠
毒性类型：急性
毒性作用： 详细的毒副作用没有报告以外的其他致死剂量值
2 。
试验方法：吸入
摄入剂量： “ 1170年mg/m3/8H
测试对象：啮齿动物-鼠
毒性类型：急性
毒性作用： 详细的毒副作用没有报告以外的其他致死剂量值
3 。
试验方法：口服
摄入剂量： 2800毫克/千克
测试对象：啮齿动物-鼠
毒性类型：急性
毒性作用： 详细的毒副作用没有报告以外的其他致死剂量值
生态学数据:
该物质对环境可能有危害，对水体应给予特别注意。
CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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QK9275000
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CHEMICAL NAME :
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Naphthenic acid, zinc salt
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CAS REGISTRY NUMBER :
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12001-85-3
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LAST UPDATED :
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199710
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration into the eye
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SPECIES OBSERVED :
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Rodent - rabbit
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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4920 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LC - Lethal concentration
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ROUTE OF EXPOSURE :
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Inhalation
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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>1170 mg/m3/8H
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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2800 mg/kg
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TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD - Lethal dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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>5 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD - Lethal dose
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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>2 gm/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Bird - wild bird species
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DOSE/DURATION :
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2250 mg/kg
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TOXIC EFFECTS :
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Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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9380 mg/kg/
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SEX/DURATION :
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female 6-15 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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940 mg/kg
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SEX/DURATION :
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female 6-15 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
MUTATION DATA
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TYPE OF TEST :
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Cytogenetic analysis
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TEST SYSTEM :
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Rodent - hamster Ovary
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DOSE/DURATION :
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70 mg/L
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REFERENCE :
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NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD-A180-019 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83788 No. of Facilities: 2519 (estimated) No. of Industries: 45 No. of Occupations: 38 No. of Employees: 27450 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83788 No. of Facilities: 5128 (estimated) No. of Industries: 66 No. of Occupations: 54 No. of Employees: 96185 (estimated) No. of Female Employees: 18248 (estimated)
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