80890-07-9

• 常用中文名：(+)-硝苯地平
• 常用英文名：(+)-Nitrendipine
• CAS号：80890-07-9
• 分子式：C₁₈H₂₀N₂O₆
• 分子量：360.36100
• 发布时间：2017-05-16 12:37:08
• 更新时间：2026-07-04 09:44:16

名称

• 中文名: (+)-硝苯地平
• 英文名: 5-O-ethyl 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
• 中文别名: 尼群地平杂质
• 英文别名: (R)-(+)-Nitrendipine; 3,5-Pyridinedicboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester, (4R); 3,5-Pyridinedicboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester, (4R)- (9CI); (R)-Nitrendipine; (R)-2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicboxylic acid 3-methyl 5-ethyl ester; [R,(+)]-2,6-Dimethyl-4β-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicboxylic acid 3-methyl 5-ethyl ester; Lopac-N-144; (+)-(R)-Nitrendipine; R-nitrendipine; 3,5-Pyridinedicboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester, (R); Nitrendipine Impurity1219; Tocris-0601

物化性质

• 密度: 1.247g/cm3
• 沸点: 488.9ºC at 760 mmHg
• 分子式: C₁₈H₂₀N₂O₆
• 分子量: 360.36100
• 闪点: 249.5ºC
• 精确质量: 360.13200
• PSA: 110.45000
• LogP: 3.41770
• 折射率: 1.553

合成路线

39562-70-4 ~% 80890-07-9 80873-62-7

文献：Barbato, Francesco; Quaglia, Fabiana; Quercia, Maria Tiziana; La Rotonda, Maria Immacolata Helvetica Chimica Acta, 2000 , vol. 83, # 4 p. 767 - 776