80873-62-7

• 常用中文名：(-)-硝苯地平
• 常用英文名：(-)-Nitrendipine
• CAS号：80873-62-7
• 分子式：C₁₈H₂₀N₂O₆
• 分子量：360.36100
• 发布时间：2016-11-08 12:51:37
• 更新时间：2026-07-08 23:37:40

名称

• 中文名: (-)-硝苯地平
• 英文名: Ethyl methyl (4S)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5- pyridinedicarboxylate
• 中文别名: 尼群地平杂质
• 英文别名: Nitrendipine Impurity1220; (S)-(-)-Nitrendipine; 3,5-Pyridinedicboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester, (4S); 3,5-Pyridinedicboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester, (4S)- (9CI); (S)-2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicboxylic acid 3-methyl 5-ethyl ester; (S)-Nitrendipine; (-)-(S)-Nitrendipine; 3,5-Pyridinedicboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, ethyl methyl ester, (S); [S,(-)]-2,6-Dimethyl-4α-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicboxylic acid 3-methyl 5-ethyl ester

物化性质

• 密度: 1.247g/cm3
• 沸点: 488.9ºC at 760 mmHg
• 分子式: C₁₈H₂₀N₂O₆
• 分子量: 360.36100
• 闪点: 249.5ºC
• 精确质量: 360.13200
• PSA: 110.45000
• LogP: 3.41770
• 折射率: 1.553

合成路线

64-17-5 88712-56-5 ~% 80873-62-7

文献：Cheng, Zhi-Gang; Dai, Xu-Yong; Li, Li-Wei; Wan, Qiong; Ma, Xiang; Xiang, Guang-Ya Molecules, 2014 , vol. 19, # 1 p. 1344 - 1352

99-61-6 ~% 80873-62-7

文献：Cheng, Zhi-Gang; Dai, Xu-Yong; Li, Li-Wei; Wan, Qiong; Ma, Xiang; Xiang, Guang-Ya Molecules, 2014 , vol. 19, # 1 p. 1344 - 1352

75130-24-4 ~% 80873-62-7

文献：Cheng, Zhi-Gang; Dai, Xu-Yong; Li, Li-Wei; Wan, Qiong; Ma, Xiang; Xiang, Guang-Ya Molecules, 2014 , vol. 19, # 1 p. 1344 - 1352

74936-72-4 ~% 80873-62-7

文献：Cheng, Zhi-Gang; Dai, Xu-Yong; Li, Li-Wei; Wan, Qiong; Ma, Xiang; Xiang, Guang-Ya Molecules, 2014 , vol. 19, # 1 p. 1344 - 1352

39562-70-4 ~% 80890-07-9 80873-62-7

文献：Barbato, Francesco; Quaglia, Fabiana; Quercia, Maria Tiziana; La Rotonda, Maria Immacolata Helvetica Chimica Acta, 2000 , vol. 83, # 4 p. 767 - 776