645405-18-1

• 常用中文名：4-chloro-5-hydroxy-2-(oxan-2-yl)pyridazin-3-one
• 常用英文名：4-chloro-5-hydroxy-2-(oxan-2-yl)pyridazin-3-one
• CAS号：645405-18-1
• 分子式：C₉H₁₁ClN₂O₃
• 分子量：230.64800
• 发布时间：2017-09-28 06:13:34
• 更新时间：2024-01-29 23:35:51

名称

• 英文名: 4-chloro-5-hydroxy-2-(oxan-2-yl)pyridazin-3-one
• 英文别名: 3(2H)-Pyridazinone,4-chloro-5-hydroxy-2-(tetrahydro-2H-pyran-2-yl)

物化性质

• 分子式: C₉H₁₁ClN₂O₃
• 分子量: 230.64800
• 精确质量: 230.04600
• PSA: 64.35000
• LogP: 1.30140

合成路线

173206-13-8 ~90% 645405-18-1

文献：NEUROCRINE BIOSCIENCES, INC. Patent: WO2005/103039 A1, 2005 ; Location in patent: Page/Page column 36 ; WO 2005/103039 A1

173206-12-7 ~87% 645405-18-1

文献：Ma, Chen; Cho, Su-Dong; Falck; Shin, Dong-Soo Heterocycles, 2004 , vol. 63, # 1 p. 75 - 85

110-87-2 ~% 645405-18-1

文献：Dyck, Brian; Markison, Stacy; Zhao, Liren; Tamiya, Junko; Grey, Jonathan; Rowbottom, Martin W.; Zhang, Mingzhu; Vickers, Troy; Sorensen, Katie; Norton, Christi; Wen, Jenny; Heise, Christopher E.; Saunders, John; Conlon, Paul; Madan, Ajay; Schwarz, David; Goodfellow, Val S. Journal of Medicinal Chemistry, 2006 , vol. 49, # 13 p. 3753 - 3756