645405-18-1

645405-18-1 structure

645405-18-1 structure

Name: 4-chloro-5-hydroxy-2-(oxan-2-yl)pyridazin-3-one
Chemical Name: 4-chloro-5-hydroxy-2-(oxan-2-yl)pyridazin-3-one
CAS Number: 645405-18-1
Molecular Formula: C₉H₁₁ClN₂O₃
Molecular Weight: 230.64800
Create Date: 2017-09-28 06:13:34
Modify Date: 2024-01-29 23:35:51

Name	4-chloro-5-hydroxy-2-(oxan-2-yl)pyridazin-3-one
Synonyms	3(2H)-Pyridazinone,4-chloro-5-hydroxy-2-(tetrahydro-2H-pyran-2-yl)

Molecular Formula	C₉H₁₁ClN₂O₃
Molecular Weight	230.64800
Exact Mass	230.04600
PSA	64.35000
LogP	1.30140

173206-13-8 structure

173206-13-8

~90%

645405-18-1 structure

645405-18-1

Literature: NEUROCRINE BIOSCIENCES, INC. Patent: WO2005/103039 A1, 2005 ; Location in patent: Page/Page column 36 ; WO 2005/103039 A1

173206-12-7 structure

173206-12-7

~87%

645405-18-1 structure

645405-18-1

Literature: Ma, Chen; Cho, Su-Dong; Falck; Shin, Dong-Soo Heterocycles, 2004 , vol. 63, # 1 p. 75 - 85

110-87-2 structure

110-87-2

~%

645405-18-1 structure

645405-18-1

Literature: Dyck, Brian; Markison, Stacy; Zhao, Liren; Tamiya, Junko; Grey, Jonathan; Rowbottom, Martin W.; Zhang, Mingzhu; Vickers, Troy; Sorensen, Katie; Norton, Christi; Wen, Jenny; Heise, Christopher E.; Saunders, John; Conlon, Paul; Madan, Ajay; Schwarz, David; Goodfellow, Val S. Journal of Medicinal Chemistry, 2006 , vol. 49, # 13 p. 3753 - 3756