753475-15-9

• 常用中文名：11-(1-哌嗪基)-二苯并[B,F][1,4]噻嗪盐酸盐
• 常用英文名：11-(1-Piperazinyl)dibenzo[b,f][1,4]thiazepine hydrochloride (1:1)
• CAS号：753475-15-9
• 分子式：C₁₇H₁₈ClN₃S
• 分子量：331.86300
• 发布时间：2016-03-04 12:04:50
• 更新时间：2026-07-16 19:47:45

名称

• 中文名: 11-(1-哌嗪基)-二苯并[B,F][1,4]噻嗪盐酸盐
• 英文名: 11-(1-Piperazinyl)dibenzo[b,f][1,4]thiazepine hydrochloride (1:1)
• 中文别名: 喹硫平杂质28 盐酸盐; 喹硫平杂质28 盐酸盐(喹硫平杂质B盐酸盐); 10-(PIPERAZIN-1-YL)-2-THIA-9-AZATRICYCLO[9.4.0.03卓化物; 11-(1-哌嗪基)二苯并[B,F][1,4]硫氮杂卓盐酸盐(1:1)
• 英文别名: 10-(piperazin-1-yl)-2-thia-9-azatricyclo[9.4.0.03,]pentadeca-1,3,5,7,9,11,13-htaene hydrochloride; 11-(1-Piperazinyl)dibenzo[b,f][1,4]thiazine hydrochloride; 11-Phthalimido-undecansaeure; Quetiapine Impurity 28 Hydrochloride（Quetiapine Impurity B Hydrochloride ); Norquetiapine hydrochloride solution; 11-Piperazinyl Dibenzo [b, f] [1, 4] Thiazine. Hydrochloride; Norquetiapine hydrochloride; 11-piperazin-1-yldibenzo[b,f][1,4]thiazine hydrochloride; 11-(1-PIPERAZINYL)-DIBENZO[B,F][1,4]THIAZIN HYDROCHLORIDE; 11-phthalimido-undecanoic acid; 11-Piperazinodibenzo[B,F][1,4]Thiazine Hydrochloride

物化性质

• 沸点: 489.5ºC at 760 mmHg
• 分子式: C₁₇H₁₈ClN₃S
• 分子量: 331.86300
• 闪点: 249.9ºC
• 精确质量: 331.09100
• PSA: 52.93000
• LogP: 3.63900

安全

• 符号: GHS02, GHS06, GHS08
• 信号词: Danger
• 危害声明: H225-H301 + H311 + H331-H370
• 警示性声明: P210-P260-P280-P301 + P310-P311
• 危险品运输编码: UN1230 - class 3 - PG 2 - Methanol, solution

合成路线

110-85-0 3159-07-7 ~92% 753475-15-9

文献：USV LIMITED Patent: WO2007/4234 A1, 2007 ; Location in patent: Page/Page column 12 ;

5747-48-8 ~% 753475-15-9

文献：ASTRAZENECA AB Patent: WO2006/73360 A1, 2006 ; Location in patent: Page/Page column 10-11 ; WO 2006/073360 A1

110-85-0 13745-86-3 ~87% 753475-15-9

文献：Niphade, Navnath C.; Mali, Anil C.; Pandit, Bhushan S.; Jagtap, Kunal M.; Jadhav, Sanjay A.; Jachak, Madhukar N.; Mathad, Vijayavitthal T. Organic Process Research and Development, 2009 , vol. 13, # 4 p. 792 - 797