38092-88-5

• 常用中文名：8-脱氯-9-氯-N-甲基地氯雷他定
• 常用英文名：9-chloro-11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine
• CAS号：38092-88-5
• 分子式：C₂₀H₂₁ClN₂
• 分子量：324.84700
• 发布时间：2017-04-19 20:53:13
• 更新时间：2026-07-10 12:26:07

名称

• 中文名: 8-脱氯-9-氯-N-甲基地氯雷他定
• 英文名: 9-chloro-11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine
• 中文别名: 地氯雷他定杂质5; 地氯雷他定杂质27; 去氯雷他定杂质5; 地氯雷他定杂质35
• 英文别名: 9-chloro-11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohta[2,4-b]pyridine; Desloratadine Impurity 27; 9-chloro azatadine; 9-Chloro-6,11-dihydro-11-(1-Methyl-4-piperidinylidene); Desloratadine Impurity 24; Desloratadine Impurity 35; 9-Chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 9-chloro-11-(1-methyl-piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; 8-Dechloro-9-chloro-N-Methyl Desloratadine; 5H-Benzo[5,6]cyclohta[1,2-b]pyridine, 9-chloro-6,11-dihydro-11-(1-methyl-4-piperidinylidene); 8-Dechloro-9-chloro-N-methyl Desloratadine; 9-chloro-11-(1-methylpiperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohta[1,2-b]pyridine

物化性质

• 分子式: C₂₀H₂₁ClN₂
• 分子量: 324.84700
• 精确质量: 324.13900
• PSA: 16.13000
• LogP: 4.29900

合成路线

3964-84-9 ~% 38092-88-5

文献：Piwinski, John J.; Wong, Jesse K.; Green, Michael J.; Ganguly, Ashit K.; Billah, M. Motasim; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 457 - 461

32998-95-1 ~% 38092-88-5

文献：Piwinski, John J.; Wong, Jesse K.; Green, Michael J.; Ganguly, Ashit K.; Billah, M. Motasim; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 457 - 461

31255-55-7 ~% 38092-88-5

文献：Piwinski, John J.; Wong, Jesse K.; Green, Michael J.; Ganguly, Ashit K.; Billah, M. Motasim; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 457 - 461

104-83-6 ~% 38092-88-5

文献：Piwinski, John J.; Wong, Jesse K.; Green, Michael J.; Ganguly, Ashit K.; Billah, M. Motasim; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 457 - 461

63463-36-5 ~% 38092-88-5

文献：Piwinski, John J.; Wong, Jesse K.; Green, Michael J.; Ganguly, Ashit K.; Billah, M. Motasim; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 457 - 461

38089-91-7 ~% 38092-88-5

文献：Piwinski, John J.; Wong, Jesse K.; Green, Michael J.; Ganguly, Ashit K.; Billah, M. Motasim; et al. Journal of Medicinal Chemistry, 1991 , vol. 34, # 1 p. 457 - 461

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