109537-11-3

• 常用中文名：8-去氯-9-氯氯雷他定
• 常用英文名：Loratadine Impurity 19
• CAS号：109537-11-3
• 分子式：C₂₂H₂₃ClN₂O₂
• 分子量：382.88300
• 发布时间：2016-05-11 17:54:30
• 更新时间：2026-07-06 18:52:39

名称

• 中文名: 8-去氯-9-氯氯雷他定
• 英文名: ethyl 4-(9-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate
• 中文别名: 地氯雷他定杂质31; 8-脱氯-9-氯氯雷他定
• 英文别名: Loratadine 8-Dechloro-9-Chloro Impurity; 4-(9-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohta[1,2-b]pyridin-11-ylidene)-1-piperidinecboxylic Acid Ethyl Ester; 8-Dechloro-9-chloro Loratadine; ethyl 4-(9-chloro-5H-benzo; Desloratadine Impurity 31; Ethyl 4-(9-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxyate; 4-(9-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic Acid Ethyl Ester; Ethyl 4-(9-Chloro-5,6-dihydro-11H-benzo[5,6] cyclohta[1,2-b]pyridin-11-ylidene)-1-piperidinecboxyate; 1-Piperidinecboxylic acid, 4-(9-chloro-5,6-dihydro-11H-benzo[5,6]cyclohta[1,2-b]pyridin-11-ylidene)-, ethyl ester

物化性质

• 分子式: C₂₂H₂₃ClN₂O₂
• 分子量: 382.88300
• 精确质量: 382.14500
• PSA: 42.43000
• LogP: 4.82570
• 储存条件: 2-8°C， 避光

合成路线

541-41-3 38092-88-5 ~52% 109537-11-3

文献：Arzneimittel-Forschung/Drug Research, , vol. 36, # 9 p. 1311 - 1314

3964-84-9 ~% 109537-11-3

文献：Journal of Medicinal Chemistry, , vol. 34, # 1 p. 457 - 461

32998-95-1 ~% 109537-11-3

文献：Journal of Medicinal Chemistry, , vol. 34, # 1 p. 457 - 461

31255-55-7 ~% 109537-11-3

文献：Journal of Medicinal Chemistry, , vol. 34, # 1 p. 457 - 461

104-83-6 ~% 109537-11-3

文献：Journal of Medicinal Chemistry, , vol. 34, # 1 p. 457 - 461

63463-36-5 ~% 109537-11-3

文献：Journal of Medicinal Chemistry, , vol. 34, # 1 p. 457 - 461

38089-91-7 ~% 109537-11-3

文献：Journal of Medicinal Chemistry, , vol. 34, # 1 p. 457 - 461

上下游产品

上游产品  5
541-41-3 38092-88-5 32998-95-1 104-83-6
63463-36-5
下游产品  1
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