256925-92-5

• 常用中文名：千层纸素A-7-0-Β-D-葡萄糖醛酸苷
• 常用英文名：Cimigenol-3-O-alpha-L-arabinoside
• CAS号：256925-92-5
• 分子式：C₃₅H₅₆O₉
• 分子量：620.814
• 相关类别： 天然产物 萜类
• 发布时间：2016-06-09 21:24:16
• 更新时间：2026-07-04 07:39:39
• Cimiracemoside C 是升麻中的有效成分,可激活 AMPK,具有抗糖尿病的潜力。

名称

• 中文名: 千层纸素A-7-0-Β-D-葡萄糖醛酸苷
• 英文名: Cimiracemoside C
• 中文别名: 升麻酮醇-3-O-Α-L-拉伯糖苷(对照品); 升麻环氧醇 3-阿拉伯吡喃糖苷, 来源于升麻; 升麻醇-3-O-Α-L-拉伯糖苷; 升麻酮醇 3-O-ALPHA-L-拉伯糖苷; 升麻醇-3-O-Α-L-阿拉伯糖苷; 千层纸素A-Β-D-葡萄糖醛酸苷,10 MM DMSO 溶液; 升麻醇3-Α-L-阿拉伯糖苷; 升麻醇-3-O-Α-L-阿拉伯糖苷/HPLC; 升麻醇-3-O-α-L-阿拉伯糖苷
• 英文别名: Cimigenol-3-O-abinoside; CIMIRACEMOSIDE C(SH); CiMigenol-3- O-α-L–abinopyranoside; Cimigenol-3-O-Alpha-L-arabinoside; (1S,2R,3S,4R,7R,9S,12R,14S,17R,18R,19R,21R,22S)-2-Hydroxy-22-(2-hydroxy-2-propanyl)-3,8,8,17,19-pentamethyl-23,24-dioxaheptacyclo[19.2.1.0.0.0.0.0]tetracos-9-yl α-L- arabinopyranoside; CiMigenol-3- O-α-L –abinopyranoside,CiMiraceMoside C; Cimigenol-3-O-α-L-abinoside, Cimigenol 3-O-alpha-L-abinopyranoside; a-L-abinopyranoside, (3b,15a,16a,23R,24S)-16,23:16,24-dioxy-15,25-dihydroxy-9,19-cyclolanostan-3-yl; Cimigenol 3-α-L-abinoside-RM; CIMIRACEMOSIDE C; (2R,3R,4R,5R)-2-[[(1S,2R,3S,4S,7S,9S,12S,14R,17R,18R,19S,21R,22R)-2-Hydroxy-22-(2-hydroxypropan-2-yl; Cimigenol 3-O-alpha-L-abinopyranoside; α-L-abinopyranoside, (3β,15α,16α,23R,24S)-16,23:16,24-dioxy-15,25-dihydroxy-9,19-cyclolanostan-3-yl; CIMIGENOL-3-O-A-L-ABINOPYRAN; Cimigenol 3- -L-abinoside; α-L-Arabinopyranoside, (2S,4aR,5aS,7aR,7bR,8R,10R,11S,12aS,13R,13aS,13bR,15aR)-heptadecahydro-13-hydroxy-11-(1-hydroxy-1-methylethyl)-1,1,7a,8,13a-pentamethyl-10,12a-epoxy-2H,5H-cyclopropa[1',8'a] naphth[2',1':4,5]indeno[2,1-b]oxepin-2-yl; Cimigenol 3-O-alpha-L-abinoside; CIMICIFUGOSIDE M; CIMICIFUGOSIDE M; CIMIRACEMOSIDE C; Cimigenol 3-α- L -abinoside; Cimigenol 3-O-α-L-abinosid; (2S,3R,4S,5S)-2-(((2,4S,6,7aS,9,9bR,10R,12R,13S,14aS,15R,15aS,15bR)-15-hydroxy-13-(2-hydroxypropan-2-yl)-3,3,9a,10,15a-pentamethyloctadecahydro-1H-12,14a-oxycyclopropa[1',8a']naphtho[2',1':4,5]indeno[2,1-b]oxin-4-yl)oxy)tetrahydro-2H-pyran-3,4,5-triol; Cimigenol 3-abinopyranoside from Cimicifuga foetida L; Cimiracemoside C, 10 mM in DMSO

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 740.3±60.0 °C at 760 mmHg
• 熔点: 258-260℃
• 分子式: C₃₅H₅₆O₉
• 分子量: 620.814
• 闪点: 401.5±32.9 °C
• 精确质量: 620.392456
• PSA: 138.07000
• LogP: 5.82
• 外观性状: 晶体
• 蒸汽压: 0.0±5.5 mmHg at 25°C
• 折射率: 1.607
• 储存条件: 2-8℃，干燥，密闭

生物活性

• 描述: Cimiracemoside C 是升麻中的有效成分,可激活 AMPK,具有抗糖尿病的潜力。
• 相关类别:
  信号通路 >> 表观遗传学 >> AMPK
  信号通路 >> PI3K/Akt/mTOR 信号通路 >> AMPK
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Moser C, et al. Antidiabetic effects of the Cimicifuga racemosa extract Ze 450 in vitro and in vivo in ob/ob mice. Phytomedicine. 2014 Sep 25;21(11):1382-9.

安全

• 危害码 (欧洲): Xi