49710-99-8

• 常用中文名：2'-hydroxy-5'-methoxypropiophenone
• 常用英文名：2'-hydroxy-5'-methoxypropiophenone
• CAS号：49710-99-8
• 分子式：C₁₀H₁₂O₃
• 分子量：180.20000
• 发布时间：2016-04-27 15:24:26
• 更新时间：2024-01-11 09:29:03

名称

• 英文名: 1-(2-hydroxy-5-methoxyphenyl)propan-1-one
• 英文别名: EINECS 256-440-0; Propiophenone,2'-hydroxy-5'-methoxy; 2'-Hydroxy-5'-methoxypropiophenone

物化性质

• 密度: 1.126g/cm3
• 沸点: 287.3ºC at 760mmHg
• 分子式: C₁₀H₁₂O₃
• 分子量: 180.20000
• 闪点: 110.7ºC
• 精确质量: 180.07900
• PSA: 46.53000
• LogP: 1.99350
• 折射率: 1.531

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UH2150000 CHEMICAL NAME : Propiophenone, 2'-hydroxy-5'-methoxy- CAS REGISTRY NUMBER : 49710-99-8 BEILSTEIN REFERENCE NO. : 1944126 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C10-H12-O3 MOLECULAR WEIGHT : 180.22 WISWESSER LINE NOTATION : 2VR BQ EO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 8,32,1973

合成路线

13098-94-7 ~73% 49710-99-8

文献：Martin, Robert Monatshefte fuer Chemie, 1981 , vol. 112, p. 1155 - 1164

5803-30-5 ~% 49710-99-8

文献：Zhang, Yi; Lee, Yong Sok; Rothman, Richard B.; Dersch, Christina M.; Deschamps, Jeffrey R.; Jacobson, Arthur E.; Rice, Kenner C. Journal of Medicinal Chemistry, 2009 , vol. 52, # 23 p. 7570 - 7579

13098-94-7 79-03-8 ~12% 49710-99-8 80427-25-4

文献：Martin, Robert Monatshefte fuer Chemie, 1981 , vol. 112, p. 1155 - 1164

79-03-8 150-78-7 ~% 49710-99-8

文献：Shulgin; Dyer Journal of Medicinal Chemistry, 1975 , vol. 18, # 12 p. 1201 - 1204

123-62-6 150-78-7 ~% 49710-99-8

文献：Ide; Baltzly Journal of the American Chemical Society, 1948 , vol. 70, p. 1084,1086

79-03-8 150-78-7 ~% 49710-99-8 5803-30-5

文献：Ide; Baltzly Journal of the American Chemical Society, 1948 , vol. 70, p. 1084,1086

150-76-5 ~% 49710-99-8

文献：Casadio; Pala; Crescenzi; Marazzi-Uberti; Fresia Arzneimittel-Forschung, 1966 , vol. 16, # 5 p. 592 - 596

938-46-5 ~% 49710-99-8

文献：Legrand Bulletin de la Societe Chimique de France, 1959 , p. 1599,1602