31858-66-9

• 常用中文名：麦考酚酸甲酯-d6(EP杂质E)
• 常用英文名：Mycophenolic Acid Methyl Ester
• CAS号：31858-66-9
• 分子式：C₁₈H₂₂O₆
• 分子量：334.36400
• 相关类别： 研究领域 其他
• 发布时间：2017-12-13 14:16:34
• 更新时间：2026-07-21 08:16:19
• Methyl mycophenolate 是霉酚酸的甲酯,也存在于海洋真菌 Phaeosphaeria spartinae 中。

名称

• 中文名: 霉酚酸甲酯
• 英文名: methyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
• 中文别名: (4E)-6-(4-羟基-6-甲氧基-7-甲基-3-氧代-1,3-二氢异苯并呋喃-5-基)-4-甲基己-4-烯酸甲酯; 霉酚酸杂质E; 吗替麦考酚酯杂质E对照品; 吗替麦考酚酯杂质10; 霉酚酸酯MOFETIL 杂质E; 麦考酚酸甲酯杂质E); 霉酚酸酯杂质E,10 MM DMSO 溶液; 吗替麦考酚酯杂质E 标准品; (E)-6-(4-羟基-6-甲氧基-7-甲基-3-氧代-1,3-二氢异苯并呋喃-5-基)-4-甲基己-4-烯酸甲酯; 吗替麦考酚酯杂质5(吗替麦考酚酯杂质E); 霉酚酸酯杂质E; 吗替麦考酚酯杂质E; 霉酚酸杂质4; 吗替麦考酚酯杂质05; 吗替麦考酚酸杂质E
• 英文别名: (E)-methyl-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate; Methyl mycophenolate impurity E; Mycophenolate methyl ester/ Mycophenolate Mofetil Impurity E; (4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid Methyl Ester; Methyl mycophenolate, 10 mM in DMSO; Mycophenolic Acid Methyl Ester/Mycophenolate Mofetil Impurity E/Mycophenolic Acid Methyl Ester/(4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid Methyl Ester; UNII-0B5C0EG8E8; Methyl Mycophenolate Impurity E); Methyl (4E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoat; MPA-OMe; Mycophenolate Mofetil Impurity 5(Mycophenolate Mofetil Impurity E); Methyl (4E)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate; Methyl mycophenolate,Inhibitor,sptinae,Methyl,Phaeosphaeria,ester,inhibit; mycophenolic Impurity E; Mycophenolate Mofetil IMP-E; Mycophenolate Mofetil Impurity E (Mycophenolic Acid Methyl Ester); 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, methyl ester, (4E); Mycophenolate Mofetil Impurity 5; Mycophenolate Mofetil IMpurity E; mucophenolic acid; methyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3- dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate; Methyl (4E)-6-(4-Hydroxy-6-methoxy; Mycophenolate Mofetil Impurity E/Mycophenolic Acid Methyl Ester/(4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid Methyl Ester; methyl mycophenolate; Impurity E

物化性质

• 密度: 1.222g/cm3
• 沸点: 540.4ºC at 760 mmHg
• 熔点: 105-106ºC
• 分子式: C₁₈H₂₂O₆
• 分子量: 334.36400
• 闪点: 194.1ºC
• 精确质量: 334.14200
• PSA: 82.06000
• LogP: 2.82160
• 折射率: 1.556
• 储存条件: 室温

生物活性

• 描述: Methyl mycophenolate 是霉酚酸的甲酯,也存在于海洋真菌 Phaeosphaeria spartinae 中。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Elsebai MF. Secondary metabolites from the marine-derived fungus Phaeosphaeria spartinae. Nat Prod Res. 2019 Aug 23:1-6.

  [2]. Gainer FE, et al. Thin-layer chromatography of mycophenolic acid and related compounds. J Chromatogr. 1971 Feb 3;54(3):446-8.

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