119141-89-8

• 常用中文名：奥美拉唑
• 常用英文名：(+)-omeprazole
• CAS号：119141-89-8
• 分子式：C₁₇H₁₉N₃O₃S
• 分子量：345.416
• 发布时间：2018-05-31 08:00:00
• 更新时间：2026-06-29 19:03:25

名称

• 中文名: 奥美拉唑
• 英文名: (R)-omeprazole
• 中文别名: R-奥美拉唑钠; 奥美拉唑杂质N(艾司奥美拉唑镁杂质F); 杂质B(R-奥美拉唑); (R)-5-甲氧基-2-((((4-甲氧基-3,5-二甲基吡啶-2-基)甲基)亚磺酰基)-1H-苯并[D]咪唑(埃索美拉唑杂质); R-对映体; 埃索美拉唑镁杂质F; (R)-5-甲氧基-2-(((4-甲氧基-3,5-二甲基吡啶-2-基)甲基)亚磺酰基)-1H-苯并[D]咪唑; 奥美拉唑杂质对照品; 埃索美拉唑镁二水合物杂质F; 奥美拉唑杂质N; 埃索美拉唑杂质6单体; (R)-奥美拉唑; (R)-6-甲氧基-2-[[(4-甲氧基-3,5-二甲基-2-吡啶基)甲基]亚磺酰基]-1H-苯并咪唑; 艾司奥美拉唑杂质F; 化合物 (R)-OMRAZOLE; 奥美拉唑R-异构体杂质; 艾司奥美拉唑钠杂质 15
• 英文别名: mepral; Omrazole Impurity 33; Omrazole impurity 18/(R)-Omrazole/(R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole; R-Omazole; R-(+)-OMRAZOLE; gastrogard; ANTRA; (S)-OMRAZOLE; Esomrazole magnesium dihydrate Impurity F; LOSEC; Esomrazole magnesium Impurity F; mopral; Esomrazole Sodium Impurity 15; OMRAL; 5-Methoxy-2-{(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl}-1H-benzimidazole; GASTROLOC; h 168/68; Omrazole impurity N (R)-Omrazole; PRILOSEC; MOPRAL; zoltum; omrazole impurity B (r-omrazole); 5-METHOXY-2-[[(4-METHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYL]SULFINYL]-1H-BENZIMIDAZOLE; (R)-5-Methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-1H-benzo[d]imidazole (Esomrazole Impurity）; /68; Trimethoprim Impurity 17; Omrazole Impurity N (Esomrazole-magnesium Impueity F); Erythromycine Thiocynate; Esomrazole Impurity F; gastroloc; omeprazole; 5-METHOXY-2[(4-METHOXY-3,5-DIMETHYL-2-PYRIDYL)METHYLSULFINYL]-1H-BENZIMIDAZOLE; ZOLTUM; GASTROGD; losec; (R)-(+)-omeprazole; 5-Methoxy-2-[(R)-[(4-Methoxy-3,5-diMethylpyridin-2-yl)Methyl]sulfinyl]-1H-benziMidazole; 1H-BenziMidazole,6-Methoxy-2-[(R)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]; (R)-5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole; (+)-omrazole; antra; (R)-6-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole; omepral; 6-Methoxy-2-[(R)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; Omrazole R-Isomer; 6-methoxy-2-[(R)-(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]-1H-benzimidazole; Omrazole Impurity N; Esomrazole Impurity 6 Monomer; prilosec; 2-[(4-METHOXY-3,5-DIMETHYLPYRID-2-YL)-METHYLSULFO]-5-METHOXYBENZIMIDAZOLE

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 600.0±60.0 °C at 760 mmHg
• 分子式: C₁₇H₁₉N₃O₃S
• 分子量: 345.416
• 闪点: 316.7±32.9 °C
• 精确质量: 345.114716
• PSA: 96.31000
• LogP: 2.17
• 外观性状: 白色固体
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.669
• 储存条件: 室温，干燥密封

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36
• 海关编码: 2941500000

合成路线

73590-85-9 ~% 119141-89-8

文献：US2008/319195 A1, ; Page/Page column 5 ;

73590-85-9 ~% 119141-89-8 119141-88-7

文献：WO2007/88559 A1, ; Page/Page column 9-10 ;

73590-58-6 ~% 119141-89-8 119141-88-7

文献：US2005/267157 A1, ; Page/Page column 10-11 ;

73590-58-6 ~% 119141-89-8

文献：Tetrahedron Asymmetry, , vol. 11, # 8 p. 1729 - 1732

上下游产品

上游产品  2
73590-85-9 73590-58-6
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海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%