137945-48-3

• 常用中文名：(6aR,10aR)-1-羟基-6,6-二甲基-3-(2-甲基辛-2-基)-6a,7,10,10a-四氢苯并[c]色原烯-9-羧酸
• 常用英文名：Lenabasum
• CAS号：137945-48-3
• 分子式：C₂₅H₃₆O₄
• 分子量：400.55100
• 发布时间：2018-12-28 18:33:36
• 更新时间：2026-10-07 19:10:47
• A synthetic nonpsychoactive cannabinoid acid with potent analgesic and anti-inflammatory activity in vivo, binds directly and selectively to PPARγ.

名称

• 中文名: (6aR,10aR)-1-羟基-6,6-二甲基-3-(2-甲基辛-2-基)-6a,7,10,10a-四氢苯并[c]色原烯-9-羧酸
• 英文名: (6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene-9-carboxylic acid
• 中文别名: (6,10-1-羟基-6,6-二甲基-3-(2-甲基辛-2-基)-6A,7,10,10A-四氢苯并[C]色原烯-9-羧酸
• 英文别名: JBT-101; CPL-7075; IP-751; EOS-62170; JBT-101/Ajulemicacid; HU-239; CT-3; DMH-THC-11-OIC; LENABASUM; 6H-Dibenzo[b,d]pyran-9-cboxylic acid, 3-(1,1-dimethylhtyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-, (6,10); Ajulemic acid; (6,10-1-Hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene-9-cboxylic acid; L-7075

物化性质

• 密度: 1.085g/cm3
• 沸点: 495.7ºC at 760mmHg
• 分子式: C₂₅H₃₆O₄
• 分子量: 400.55100
• 闪点: 158.5ºC
• 精确质量: 400.26100
• PSA: 66.76000
• LogP: 6.31580
• 蒸汽压: 1.2E-10mmHg at 25°C
• 折射率: 1.535

合成路线

137945-49-4 ~57% 137945-48-3

文献：Journal of Medicinal Chemistry, , vol. 35, # 17 p. 3135 - 3141

113418-02-3 ~% 137945-48-3

文献：Journal of Medicinal Chemistry, , vol. 35, # 17 p. 3135 - 3141

137945-53-0 ~% 137945-48-3

文献：Journal of Medicinal Chemistry, , vol. 35, # 17 p. 3135 - 3141

137945-57-4 ~% 137945-48-3

文献：Journal of Medicinal Chemistry, , vol. 35, # 17 p. 3135 - 3141

137945-54-1 ~% 137945-48-3

文献：Journal of Medicinal Chemistry, , vol. 35, # 17 p. 3135 - 3141