13127-18-9

• 常用中文名：红霉素A肟
• 常用英文名：Erythromycin A Oxime
• CAS号：13127-18-9
• 分子式：C₃₇H₆₈N₂O₁₃
• 分子量：748.941
• 发布时间：2018-10-02 22:16:46
• 更新时间：2026-07-02 23:00:34

名称

• 中文名: 红霉素A肟
• 英文名: Erythromycin A Oxime
• 中文别名: 红霉素A 9-肟(Z和E异构体的混合物); 克拉霉素杂质J; 红霉素氧亚胺; (E)-红霉素肟; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(二甲氨基)-3-羟基-6-甲基四氢-2H-吡喃-2-基)氧基)-14-乙基-7,12,13-三羟基-4-(((2R,4R,5S,6S)-5-羟基-4-甲氧基-4,6-二甲基四氢-2H-吡喃-2-基)氧基)-10-(羟基亚氨基)-3,5,7,9,11,13-六甲基氧杂环十四烷-2-酮; (9E)-红霉素A肟(外购)(未计入总数); 9-红霉素A肟; (9Z/E)-红霉素A肟(Z 和 E 异构体混合物); 罗红霉素杂质 C; 红霉素肟; 红霉素中间体; 阿奇霉素中国药典杂质S; 罗红霉素杂质C(克拉霉素杂质J); 9-红霉素A肟克拉霉素杂质J
• 英文别名: 9-Hydroxyimino-9-deoxoerythromycin A; 9-(Hydroxyimino)-9-deoxoerythromycin; Clithromycin Impurity J; Erythromycin A Oxime (Roxithromycin Impurity C); Roxithromycin Impurity C(Clithromycin Impurity J); lithromycin Impurity J; ERYTHROMYCIN-9-OXIME; Azithromycin Impurity S (9-Erythromycin A Oxime/ Erythromycin Oxime/ Roxithromycin Impurity C/ Clithromycin Impurity J); 9-O-Erythromycin oxime; ERYTHROMYCIN A 9-OXIME; ERYTHROMYCIN A 9-OXIME (E); RoxithroMycin IMpurity C; Erythromycin A Oxime (Clithromycin Impurity J); (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydro; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(hydroxyimino)-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one; Azithromycin Impurity 19; Clithromycin Impurity J (Roxithromycin Impurity C/ Erythromycin Oxime/ Azithromycin Impurity S/ 9-Erythromycin A Oxime); ERYTHROMYCIN OXIME; Erythromycin Oxime (Azithromycin Impurity S/ 9-Erythromycin A Oxime/ Roxithromycin Impurity C/ Clithromycin Impurity J); UNII-10W452CMTZ; Erythromycin A (E)-9-oxime; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-((2,6-didesoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopiranosyl)oxy)-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-((3,4,6-tridesoxy-3-dimethylamino-β-.sc.d.sc.-xylohexapiranosyl)oxy)oxacyclotetradecan-2-ona-10-oxime (E); Erythromycin A 9-Oxime (Mixture of Z and E Isomers); 9-Hydroxyimino-9-deoxoerythromycin; Roxithromycin Impurity CQ: What is Roxithromycin Impurity C Q: What is the CAS Number of Roxithromycin Impurity C Q: What is the storage condition of Roxithromycin Impurity C Q: What e the applications of Roxithromycin Impurity C; (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one; Clithromycin Impurity J/Erythromycin oxime/Erythromycin A 9-Oxime (Mixture of Z and E Isomers)/(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hy; Roxithromycin Impurity C (Erythromycin Oxime/ Azithromycin Impurity S/ 9-Erythromycin A Oxime/ Clithromycin Impurity J); (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLOXAN-2; HSDB-3074; Clarithromycin EP Impurity J; 9-ErythroMycin 9-OxiMe; CETH-001; erythromycin oxime; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethy; ERYTHERYTHROMYCIN OXIMEROMYCIN OXIME; (3R,4S,5S,6R,7R,9R,12R,13S,14R)-6-{[(2R,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-10-(hydroxyimino)-4-{[(2S,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one; Erythromycin A 9-Oxime/Clithromycin Impurity J; Erythromycin oxyme; RU-28111; 9-ErythroMycin A OxiMe; (3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino)tetra; Clithromycin Impurity 2(Clithromycin Impurity J); Erythromycin A 9-Oxime (Mixture of Z and E Isomers)/Erythromycin oxime/Clithromycin Impurity J/(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hy; HSDB3074

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 841.0±65.0 °C at 760 mmHg
• 分子式: C₃₇H₆₈N₂O₁₃
• 分子量: 748.941
• 闪点: 462.4±34.3 °C
• 精确质量: 748.472168
• PSA: 209.43000
• LogP: 3.04
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.553
• 储存条件: 室温，干燥

安全

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36

合成路线

114-07-8 ~94% 13127-18-9

文献：Chen, Mingwei; Muri, Estela M. F.; Jacob, Melissa; Williamson, John S. Medicinal Chemistry Research, 2003 , vol. 12, # 3 p. 111 - 129

114-07-8 ~% 13127-18-9 105882-69-7

文献：Magnetic Resonance in Chemistry, , vol. 39, # 6 p. 355 - 360

上下游产品

上游产品  1
114-07-8
下游产品  2
81103-11-9 80214-83-1