75262-69-0

• 常用中文名：17β-羧基-17-脱氧地塞米松
• 常用英文名：(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylic acid
• CAS号：75262-69-0
• 分子式：C₂₁H₂₇FO₄
• 分子量：362.43500
• 发布时间：2017-11-24 12:47:16
• 更新时间：2026-07-23 22:44:02

名称

• 中文名: 17β-羧基-17-脱氧地塞米松
• 英文名: (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylic acid
• 中文别名: 地塞米松酸杂质53; 17-羧基17-脱氧-地塞米松(地塞米松酸杂质); DESOXIMETASONE氧化杂质; 地塞米松-17位去羟基杂质; 17-羧基-17-二氧基-地塞米松(地塞米松酸杂质); 地塞米松杂质 53; 地塞米松酸杂质; (11Β,16Α,17Β)-9-氟-11-羟基-16-甲基-3-氧代雄甾-1,4-二烯-17-羧酸; 17-羧基-17-去氧地塞米松(地塞米松酸杂质); 17Β-羧基-17-脱氧地塞米松
• 英文别名: Androsta-1,4-diene-17-cboxylic acid, 9-fluoro-11-hydroxy-16-methyl-3-oxo-, (11β,16α,17β); Desoximetasone Oxidative Impurity; 9-Fluoro-11beta-hydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta-cboxylic Acid; 172-Cboxy-17-desoxy Dexamethasone; 17-Cboxy-17-Desoxy-Dexamethasone (Dexamethasone Acid Impurity); 17β-Cboxy-17-desoxy Dexamethasone; (11β,16α,17β)-9-Fluoro-11-hydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-cboxylic acid; 9-Fluoro-11β-hydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-cboxylic Acid; Desoximetasone Acid (25 mg) (COLD SHIPMENT) ((11Beta,16alpha,17Beta)-9-Fluoro-11-hydroxy-16-methyl-3-oxoandrosta-1,4- diene-17-cboxylic acid; Dexamethasone Acid 17-Deshydroxy Impurity; Dexamethasone-17α-dehydroxy-17β-cboxylic Acid; Dexamethasone 17-Desoxy 17β-Cboxy Impurity; (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-17-cboxylic acid; 17-Beta-Cboxy-17-Desoxy-DexaMethasone; 17β-Cboxy 17-DesoxyMethasone; Dexamethasone Impurity 33; DexaMethasone Acid IMpurity; Desoximetasone Acid; Dexamethasone Impurity 53; 17|A-Carboxy 17-Desoxymethasone; 17|A-Carboxy-17-desoxy Dexamethasone; Dexamethasone 20-Cboxy Impurity

物化性质

• 分子式: C₂₁H₂₇FO₄
• 分子量: 362.43500
• 精确质量: 362.18900
• PSA: 74.60000
• LogP: 3.30400

合成路线

382-67-2 ~% 75262-69-0

文献：Tomaskovic, Linda; Komac, Marijana; Makaruha Stegic, Oresta; Munic, Vesna; Ralic, Jovica; Stanic, Barbara; Banjanac, Mihailo; Markovic, Stribor; Hrvacic, Boska; Cipcic Paljetak, Hana; Padovan, Jasna; Glojnaric, Ines; Erakovic Haber, Vesna; Mesic, Milan; Mercep, Mladen Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 1 p. 321 - 332

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