150629-67-7

• 常用中文名：N-Fmoc-N'-[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]-D-赖氨酸
• 常用英文名：Fmoc-Lys(Dde)-OH
• CAS号：150629-67-7
• 分子式：C₃₁H₃₆N₂O₆
• 分子量：532.627
• 相关类别： 生物化工 氨基酸及其衍生物 赖氨酸类衍生物
• 发布时间：2018-12-10 19:49:07
• 更新时间：2026-07-01 14:09:20
• Fmoc-L-Lys(Dde)-OH是赖氨酸衍生物[1]。

名称

• 中文名: N-Fmoc-N’-[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]-D-赖氨酸
• 英文名: (2S)-6-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)hexanoic acid
• 中文别名: 化合物：Fmoc-Lys(Dde)-OH; N-ALPHA-FMOC-N-SILON-[1-(2,6-二氧代-4,4-二甲基亚环己基)乙基]-L-赖氨酸; N-芴甲氧羰基-N'-[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]-L-赖氨酸; FMOC-N'-[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]-L-赖氨酸; N-FMOC-N'-[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]-D-赖氨酸; DIVBIO/深创生物,Fmoc-L-Lys(Dde)-OH,N-FMOC-N-[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]-L-赖氨酸; N-FMOC-N'-DDE-L-赖氨酸E; N-FMOC-N'-[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]-赖氨酸; NΑ-FMOC-NΩ-DDE-D-赖氨酸; NΑ-[(9H-芴-9-基甲氧基)羰基]-NΕ-1-(4,4-二甲基-2,6-二氧代环己-1-亚基)乙基-L-赖氨酸; N-FMOC-N'-[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]-L-赖氨酸; DIVBIO/深创生物，Fmoc-L-Lys(Dde)-OH，N-FMOC-N-[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]-L-赖氨酸; 化合物:Fmoc-Lys(Dde)-OH; N-芴甲氧羰基-N'-[1-(4,4-二甲基-2,6-二氧代环己亚基)乙基]-D-赖氨酸
• 英文别名: N-ALPHA-FMOC-N-SILON-1-[(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDINE)ETHYL]-L-LYSINE; Nalpha-[(9H-Fluoren-9-ylmethyloxy)carbonyl]-Nsilon-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-lysine; N-ALPHA-FMOC-N-SILON-[1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEXYLIDENE)ETHYL]-D-LYSINE; FMOC-LYSINE(DDE)-OH; Nα-Fmoc-Nε-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-D-lysine, Nα-Fmoc-Nε-Dde-D-lysine; (2S)-2-(9H-fluoren-9-ylmethoxycbonylamino)-6-[1-(2-hydroxy-4,4-dimethyl-6-oxocyclohexen-1-yl)ethylideneamino]hexanoic acid; N-alpha-Fmoc-N-silon-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-L-lysine; FMOC-L-LYS(DDE); FMOC-N-SILON-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-L-LYSINE; MFCD01862894; N-ALPHA-(9-FLUORENYLMETHOXYCBONYL)-N-SILON-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-D-LYSINE; (2S)-6-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino]-2-(9H-fluoren-9-ylmethoxycbonylamino)hexanoicaci; (2S)-6-{[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]amino}-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid; N-ALPHA-FMOC-N-SILON-DDE-D-LYSINE; N-ALPHA-FMOC-N-SILON-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLDINE)ETHYL-L-LYSINE; (S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)amino)-6-((1-(4,4-diMethyl-2,6-dioxocyclohexylidene)ethyl)amino)hexanoic acid; N-ALPHA-FMOC-N-SILON-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-L-LYSINE; Nα-Fmoc-Nε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-D-lysine (HPLC); N6-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N2-Fmoc-L-lysine; Fmoc-L-Lys(Dde)-OH //BP; N-ALPHA-(9-FLUOR; N-ALPHA-(9-FLUORENYLMETHOXYCBONYL)-N-SILON-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-L-LYSINE; N-Fmoc-N'-Dde-L-lysin; L-Lysine, N6-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]; N-Fmoc-N'-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-L-lysine; N-Fmoc-N'-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-D-lysine; FMOC-LYS(DDE)-OH; Fmoc-F3aao(tBu)-OH; Nα-Fmoc-Nω-Dde-L-lysine; N-α-Fmoc-N-ε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-lysine; Nα-Fmoc-Nε-Dde-L-lysine, Nα-Fmoc-Nε-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-L-lysine; (R)-2-(((9H-fluoren-9-yl)methoxy)cbonylamino)-6-(1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino)hexanoic acid; AmbotzFAA1390; Fmoc-L-Lys(Dde)-OH; (9H-Fluoren-9-yl)MethOxy]carbonyl Lys(Dde)-OH; Nα-Fmoc-Nε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-lysine (HPLC); Fmoc-Lys(Dde); N(A)-fmoc-N(E)(4,4-dime.-2,6-dioxocyclo-hexylidene)et.-L-lys; Fmoc-L-Lys(Dde)-OH (2S)-6-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino]-2-(9H-fluoren-9-ylmethoxycbonylamino)hexanoic acid; FMOC-N-SILON-1-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-D-LYSINE; N-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine; FMOC-L-LYS(DDE)-OH; Nα-[(9H-Fluoren-9-ylmethyloxy)carbonyl]-Nε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-lysine; Fmoc-K(Dde)-OH; FMoc-Lys(Dde)-OH N-α-FMoc-N-ε-1-(4,4-diMethyl-2,6-dioxocyclohex-1 -ylidene)ethyl-L-lysine; Nα-Fmoc-Nε-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-L-lysine; N-ALPHA-(9-FLUORENYLMETHYLOXYCBONYL)-N-SILON-(4,4-DIMETHYL-2,6-DIOXOCYCLOHEX-1-YLIDENE)ETHYL-L-LYSINE; (S)-2-[((9H-fluoren-9-yl)methoxy)carbonylamino]-6-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethylamino]hexanoic acid

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 750.1±60.0 °C at 760 mmHg
• 熔点: -80ºC (dec.)
• 分子式: C₃₁H₃₆N₂O₆
• 分子量: 532.627
• 闪点: 407.5±32.9 °C
• 精确质量: 532.257324
• PSA: 121.80000
• LogP: 4.67
• 外观性状: 固体;White to Light yellow powder to crystal
• 蒸汽压: 0.0±2.6 mmHg at 25°C
• 折射率: 1.582
• 储存条件: −20°C
• 水溶解性: 可溶于：甲醇

生物活性

• 描述: Fmoc-L-Lys(Dde)-OH是赖氨酸衍生物[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 体外研究: 氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。
• 参考文献:

  [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

安全

• 危害码 (欧洲): Xi
• 安全声明 (欧洲): 22-24/25
• WGK德国: 3

合成路线

126-81-8 ~% 150629-67-7

文献：Tetrahedron Letters, , vol. 39, # 12 p. 1603 - 1606

94142-97-9 105047-45-8 ~% 150629-67-7

文献：Tetrahedron Letters, , vol. 39, # 12 p. 1603 - 1606

1755-15-3 105047-45-8 ~% 150629-67-7

文献：Journal of the Chemical Society, Chemical Communications, , # 9 p. 778 - 779