40834-42-2

• 常用中文名：4-甲基-5-羟基呋喃-2-酮
• 常用英文名：5-Hydroxy-4-methyl-2(5H)Furanone
• CAS号：40834-42-2
• 分子式：C₅H₆O₃
• 分子量：114.09900
• 发布时间：2018-06-09 15:42:08
• 更新时间：2026-07-03 09:18:25

名称

• 中文名: 4-甲基-5-羟基呋喃-2-酮
• 英文名: 5-Hydroxy-4-Methyl-2(5H)Furanone
• 中文别名: 异维A酸中间体/异维A酸环状物/4-甲基-5-羟基呋喃-2-酮; 环状物; 异维A酸环状物; 环状物(4-甲基-5-羟基呋喃-2-酮); 3-甲基-4-羟基丁烯酸内酯; 5-羟基-4-甲基-2,5-二氢呋喃-2-酮; 4-甲基-5羥基呋喃-2酮; 5-羟基-4-甲基呋喃-2(5H)-酮
• 英文别名: 5-HYDROXYDODECANOIC LACTONE; 5-HYDROXY-4-METHYL-5H-FURAN-2-ONE; 5-hydroxy-4-methly-2(5H); 5-Hydroxy-4-methyl-2(5H)-furanone; 4-Methyl-5-hydroxy-2(5H)-furanone; γ-Hydroxy-β-Methylbutenolide; 2(5H)-FURANONE, 5-HYDROXY-4-METHYL; MFCD07782086; 5-TYDROXY-4-METHYL-1-FURANONE; 5-HYDROXY-4-METHYL-2(5H)FURANONE; 5-hydroxy-4-methyl-2,5-dihydrofuran-2-one; Isotretinoin Ring; 5-hydroxy-4-methylfuran-2(5H)-one; 5-hyrdoxy-4-methyl-2(5H)furanone; Hydroxy-4-Methyl-2(5H)Furanone; (R,S)-5-Hydroxy-4-methyl-5H-furan-2-one; 5-Hydroxy-4-Methyl-2(5H)-Furan; 5-Hydroxy-4-methylfuran-2(5H)-one; 4-Hydroxy-3-Methylbut-2-en-4-olide; 2-hydroxy-3-methyl-2H-furan-5-one; 2(5H)-FURANONE, 5-HYDROXY-4-METHYL (INTERMEDIATES OF ISOTRETINOIN)

物化性质

• 密度: 1.349g/cm3
• 沸点: 328.1ºC at 760mmHg
• 分子式: C₅H₆O₃
• 分子量: 114.09900
• 闪点: 163.2ºC
• 精确质量: 114.03200
• PSA: 46.53000
• 折射率: 1.529
• 储存条件: 室温，干燥

安全

• 危害码 (欧洲): Xi
• 海关编码: 2932209090

合成路线

123-38-6 298-12-4 ~% 40834-42-2

文献：LUPIN LIMITED; ROY, Bhairab, Nath; SINGH, Girij, Pal; LATHI, Piyush, Suresh; MITRA, Rangan Patent: WO2012/7814 A2, 2012 ; Location in patent: Page/Page column 21-22 ;

4744-08-5 10024-89-2 6000-59-5 ~% 40834-42-2

文献：Ortho Pharmaceutical Corporation Patent: US5464865 A1, 1995 ; US 5464865 A

123-38-6 563-96-2 ~78% 40834-42-2

文献：Bourguignon, J. J.; Wermuth, C. G. Journal of Organic Chemistry, 1981 , vol. 46, # 24 p. 4889 - 4894

83803-81-0 ~99% 40834-42-2

文献：Yamano, Yumiko; Fujita, Yumi; Mizuguchi, Yukari; Nakagawa, Kimie; Okano, Toshio; Ito, Masayoshi; Wada, Akimori Chemical and Pharmaceutical Bulletin, 2007 , vol. 55, # 9 p. 1365 - 1370

203131-19-5 ~% 40834-42-2

文献：Boukouvalas, John; Lachance, Nicolas Synlett, 1998 , # 1 p. 31 - 32

616-02-4 ~4% 40834-42-2 6124-79-4 22122-36-7

文献：Johnson, Alan W.; Gowda, Gopala; Hassanali, Ahmed; Knox, John; Monaco, Sam; et al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 1734 - 1743

78920-07-7 ~% 40834-42-2

文献：Bourguignon, J. J.; Wermuth, C. G. Journal of Organic Chemistry, 1981 , vol. 46, # 24 p. 4889 - 4894

78920-13-5 ~% 40834-42-2

文献：Bourguignon, J. J.; Wermuth, C. G. Journal of Organic Chemistry, 1981 , vol. 46, # 24 p. 4889 - 4894

26315-61-7 51043-49-3 ~% 40834-42-2 109745-72-4

文献：Laugraud, Sylvain; Guingant, Andre; d'Angelo, Jean Journal of Organic Chemistry, 1987 , vol. 52, # 21 p. 4788 - 4790

上下游产品

上游产品  9
123-38-6 298-12-4 4744-08-5 10024-89-2
6000-59-5 563-96-2 83803-81-0 616-02-4
78920-07-7
下游产品  10
4759-48-2 302-79-4 3555-80-4 54709-94-3
472-86-6 6124-79-4 78920-13-5 61892-47-5
38030-57-8 791-28-6

海关

海关编码	2932209090
中文概述	2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%