6835-16-1

• 常用中文名：莨菪碱硫酸盐水合物
• 常用英文名：Hyoscyamine Sulfate
• CAS号：6835-16-1
• 分子式：C₃₄H₅₂N₂O₁₂S
• 分子量：712.848
• 发布时间：2018-02-22 08:00:00
• 更新时间：2024-01-14 19:02:55
• Hyoscyamine Sulfate

名称

• 中文名: 硫酸莨菪碱水合物
• 英文名: hyoscyamine sulfate
• 中文别名: 莨菪碱硫酸盐水合物; 硫酸莨菪碱
• 英文别名: HYOSCYAMINESULFATE,USP; Benzeneacetic acid, α-(hydroxymethyl)-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, (αS)-, sulfate, hydrate (2:1:2) (salt); HYOSCYAMINE SULPHATE; Hyoscyamine sulphate hydrate; HOSCYAMINE SULFATE USP; DL-tropic acid tropane-3endo-yl ester,sulfate; DL-Tropasaeure-tropan-3endo-ylester,Sulfat; Egacene; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate sulfate hydrate (2:1:2)

物化性质

• 分子式: C₃₄H₅₂N₂O₁₂S
• 分子量: 712.848
• 精确质量: 712.324097
• PSA: 200.98000
• LogP: 4.03700
• 外观性状: 粉末
• 储存条件: 20°C

MSDS

Section 1. Chemical Product and Company Identification Hyoscyamine sulfate Common Name/ Trade Name Hyoscyamine sulfate Section 4. First Aid Measures Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs. Skin ContactIn case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Cover the irritated skin with an emollient. Cold water may be used.Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention immediately. Serious Skin ContactNot available. InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Serious InhalationNot available. IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. Serious IngestionNot available. Section 5. Fire and Explosion Data Flammability of the Product May be combustible at high temperature. Auto-Ignition Temperature Not available. Not available. Flash Points Flammable LimitsNot available. Products of CombustionThese products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...). Fire Hazards in Presence of Slightly flammable to flammable in presence of heat. Various Substances Risks of explosion of the product in presence of mechanical impact: Not available. Explosion Hazards in Risks of explosion of the product in presence of static discharge: Not available. Presence of Various Substances Fire Fighting MediaSMALL FIRE: Use DRY chemical powder. and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet. Special Remarks onNot available. Fire Hazards Special Remarks on Explosion Not available. Hazards Section 6. Accidental Release Measures Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Large SpillPoisonous solid. Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to reduce vapors. Prevent entry into sewers, basements or confined areas; dike if needed. Eliminate all surface and allow to evacuate through the sanitary system. Hyoscyamine sulfate Section 7. Handling and Storage PrecautionsKeep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not ingest. Do not breathe dust. Wear suitable protective clothing. If ingested, seek medical advice immediately and show the container or the label. Keep container tightly closed. Keep container in a cool, well-ventilated area. Sensitive to light. Store in Storage light-resistant containers. Section 8. Exposure Controls/Personal Protection Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSafety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be a Large Spillused to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure LimitsNot available. Section 9. Physical and Chemical Properties Physical state and appearance Solid.OdorNot available. Not available. Taste Molecular Weight712.85 g/mole Not available. Color Not available. pH (1% soln/water) Boiling PointDecomposes. 206°C (402.8°F) Melting Point Critical TemperatureNot available. Specific GravityNot available. Vapor PressureNot applicable. Vapor DensityNot available. Not available. Volatility Odor ThresholdNot available. Not available. Water/Oil Dist. Coeff. Ionicity (in Water)Not available. Dispersion PropertiesSee solubility in water. SolubilitySoluble in cold water. Section 10. Stability and Reactivity Data StabilityThe product is stable. Instability TemperatureNot available. Conditions of InstabilityExcess heat Incompatibility with various Not available. substances CorrosivityNon-corrosive in presence of glass. Special Remarks onNot available. Reactivity Hyoscyamine sulfate Not available. Special Remarks on Corrosivity PolymerizationWill not occur. Section 11. Toxicological Information Routes of EntryInhalation. Ingestion. LD50: Not available. Toxicity to Animals LC50: Not available. Chronic Effects on Humans Not available. Hazardous in case of ingestion. Other Toxic Effects on Slightly hazardous in case of skin contact (irritant), of inhalation. Humans Special Remarks onNot available. Toxicity to Animals Special Remarks onNot available. Chronic Effects on Humans Special Remarks on otherMay cause skin, eye, and respiratory tract irritation. Toxic Effects on HumansHarmful if swallowed. May cause constipation. May affect behavior/central nervous system, respiratory system (dyspnea), cardiovascular system, vision. An anticholinergic agent. It can cause blurred vision, photophobia, vasodilation, rapid and weak pulse, tachydardia, hyperpyrexia, excitement, muscular incoordination, convulsions, agitation, restlessness, disturbed gait and speech, hallucinations, delirium, and pupil dilation, bradycardia. Section 12. Ecological Information EcotoxicityNot available. BOD5 and CODNot available. Possibly hazardous short term degradation products are not likely. However, long term degradation Products of Biodegradation products may arise. The products of degradation are less toxic than the product itself. Toxicity of the Products of Biodegradation Not available. Special Remarks on the Products of Biodegradation Section 13. Disposal Considerations Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental control regulations. Section 14. Transport Information DOT ClassificationCLASS 6.1: Poisonous material. UNNA: 1544 : Alkaloid salt, solid, n.o.s. (Hyoscyamine sulfate) PG: III Identification Special Provisions forNot available. Transport DOT (Pictograms) Hyoscyamine sulfate Section 15. Other Regulatory Information and Pictograms No products were found. Federal and State Regulations CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has Proposition 65found to cause cancer which would require a warning under the statute: No products were found. Warnings California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. Other RegulationsOSHA: Hazardous by definition of Hazard Communication Standard (29 CFR 1910.1200). WHMIS (Canada) CLASS D-1B: Material causing immediate and serious toxic effects (TOXIC). Other Classifications DSCL (EEC)R25- Toxic if swallowed.S45- In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). Health Hazard HMIS (U.S.A.)2 National Fire Protection 1 Flammability 1 Association (U.S.A.) Fire Hazard 2 0 Reactivity Health Reactivity 0 Specific hazard Personal Protection E WHMIS (Canada) (Pictograms) DSCL (Europe) (Pictograms) TDG (Canada) (Pictograms) ADR (Europe) (Pictograms) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Safety glasses. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 符号: GHS06
• 信号词: Danger
• 危害声明: H300 + H330
• 警示性声明: Missing Phrase - N15.00950417-P260-P304 + P340 + P310-P403 + P233
• 危险品运输编码: UN 1544PSN1 6.1 / PGII