6409-77-4

6409-77-4结构式

常用中文名：核固红
常用英文名：Nuclear Fast Red
CAS号：6409-77-4
分子式：C₁₄H₈NNaO₇S
分子量：357.271
相关类别：化学试剂有机试剂芳香醛(含缩醛,半缩醛)
发布时间：2018-06-01 08:00:00
更新时间：2024-01-06 09:59:18
核固红是一种蒽醌染料,通常与过量的铝离子结合使用,作为红色核复染。核固红已被用作钙的组织化学和比色试剂[1]。核坚牢红作为检测鸟嘌呤的高灵敏度“开/关”荧光探针[2]。

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中文名	核固红
英文名	nuclear fast red
中文别名	钙红,细胞核坚牢红,核快红核快红
英文别名	Kernechtrot NFR CALCIUM RED KERNECHTROT 2-Anthracenesulfonic acid, 4-amino-9,10-dihydro-1,3-dihydroxy-9,10-dioxo-, monosodium salt Sodium 4-amino-1,3-dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate FAST RED B Calcin red EINECS 229-088-0 NFR 2-Anthracenesulfonic acid, 4-amino-9,10-dihydro-1,3-dihydroxy-9,10-dioxo-, sodium salt (1:1) nuclear MFCD00078493 Sodium 4-amino-1,3-dihydroxy-9,10-dioxo-9,10-dihydro-2-anthracenesulfonate

描述	核固红是一种蒽醌染料,通常与过量的铝离子结合使用,作为红色核复染。核固红已被用作钙的组织化学和比色试剂[1]。核坚牢红作为检测鸟嘌呤的高灵敏度“开/关”荧光探针[2]。
相关类别	研究领域 >> 其他信号通路 >> 其他 >> 其他
参考文献	[1]. Yi Cui, et al. Nuclear fast red as highly sensitive "off/on" fluorescent probe for detecting guanine. Talanta. 2014 Dec;130:536-41. [2]. M Frank , et al. Certification procedures for nuclear fast red (Kernechtrot), CI 60760. Biotech Histochem. 2007 Feb;82(1):35-9.

熔点	300 °C
分子式	C₁₄H₈NNaO₇S
分子量	357.271
精确质量	356.991913
PSA	166.20000
LogP	2.02150
外观性状	结晶粉末
储存条件	室温

Name:	Nuclear Fast Red Material Safety Data Sheet
Synonym:	CI 60760; Calcium Re
CAS:	6409-77-4

Section 1 - Chemical Product MSDS Name:Nuclear Fast Red Material Safety Data Sheet
Synonym:CI 60760; Calcium Re

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
6409-77-4	Nuclear Fast Red		229-088-0

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause irritation with burning pain, itching and redness. May be absorbed through the skin.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May cause respiratory difficulty and coughing.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Use with adequate ventilation.
Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing.
Keep container tightly closed. Avoid ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 6409-77-4: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: dark red
Odor: Not available.
pH: 5.5-7@1g/l H2O(20C)
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: > 300 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water: 1 g/l @ 25C
Specific Gravity/Density:
Molecular Formula: C14H8NNaO7S
Molecular Weight: 357.1083

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
Incompatible materials, dust generation, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will not occur.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 6409-77-4 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Nuclear Fast Red - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 6409-77-4: No information available.
Canada
CAS# 6409-77-4 is listed on Canada's DSL List.
CAS# 6409-77-4 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 6409-77-4 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

符号	GHS07
信号词	Warning
危害声明	H315-H319-H335
警示性声明	P261-P305 + P351 + P338
个人防护装备	dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲)	Xi: Irritant;
风险声明 (欧洲)	R36/37/38
安全声明 (欧洲)	S26-S36
危险品运输编码	NONH for all modes of transport
WGK德国	3

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