4403-78-5

• 常用中文名：N,N-双(乙烯)-对甲苯磺酰胺
• 常用英文名：Benzenesulfonamide,N,N'-1,2-ethanediylbis[4-methyl
• CAS号：4403-78-5
• 分子式：C₁₆H₂₀N₂O₄S₂
• 分子量：368.47100
• 发布时间：2018-12-26 15:37:51
• 更新时间：2026-07-07 14:10:02

名称

• 中文名: N,N-双(乙烯)-对甲苯磺酰胺
• 英文名: 4-methyl-N-[2-[(4-methylphenyl)sulfonylamino]ethyl]benzenesulfonamide
• 中文别名: N,N' -二对甲苯磺酰基乙二胺; 法舒地尔杂质39; N,N-(乙烷-1,2-叉基)二(4-甲基苯磺酰胺); 法舒地尔杂质29; N,N'-(乙烷-1,2-二基)双(4-甲基苯磺酰胺); N,N'-二(对甲苯磺酰基)乙二胺; N,N'-二苯磺酰基乙二胺; N,N′-二对甲苯磺酰乙二胺
• 英文别名: 1,2-Bis(tosylamino)ethane; 1,4-bis-(p-toluenesulfonyl)-1,4-diazabutane; 4-methyl-N-(2-{[(4-methylphenyl)sulfonyl]amino}ethyl)benzenesulfonamide; N,N'-Ditosyl-1,2-ethanediamine; 1,2-(Tosylamino)ethane; N,N'-Ethylenedi-p-toluenesulfonamide; p-Toluenesulfonamide,N,N'-ethylenebis; N,N'-Bis(toluenesulfonyl)-1,2-ethylenediamine; Fasudil impurity 8/N,N'-Bis(ethylene)-p-Toluenesulfonamide; N,N'-Bis(ethylene)-p-Toluenesulfonamide; N,N’-Di-p-tosylethylenediamine; N,N'-(ethane-1,2-diyl)bis(4-methyldibenzenesulfonamide); N,N'-ethane-1,2-diylbis(4-methylbenzenesulfonamide); Benzenesulfonamide, N,N'-1,2-ethanediylbis[4-methyl; N. N '- di-p-toluenesulfonyl Ethylenediamine; N,N'-Ethylenebis(4-methylbenzenesulfonamide); N,N'-ethylenedi(toluenesulfonamide); N,N'-Ditosylethane-1,2-diamine; 4-Methyl-N-[2-[(4-methylphenyl)sulfonylamino]ethyl]benzenesulfonamide; N,N'-di-p-tosylethylenediamine; N,N'-Ditosylethylenediamine; N,N'-di(p-toluenesulfonyl)ethylenediamine; N,N'-(Ethane-1,2-diyl)bis(4-methylbenzenesulfonamide); N,N'-Ethylenebis-p-toluenesulfonamide; Fasudil impurity 9/N,N'-Bis(ethylene)-p-Toluenesulfonamide; N,N''-ETHYLENEBIS-P-TOLUENESULFONAMIDE; 4-Methyl-N-{2-[(4-methylbenzene)sulfonamido]-ethyl}benzene-1-sulfonamide; bis(4-methylbenzenesulfonamide); N,N'-bis[(4-methylphenyl)sulfonyl]-1,2-ethylenediamine

物化性质

• 密度: 1.297g/cm3
• 沸点: 549.9ºC at 760 mmHg
• 分子式: C₁₆H₂₀N₂O₄S₂
• 分子量: 368.47100
• 闪点: 286.4ºC
• 精确质量: 368.08600
• PSA: 109.10000
• LogP: 4.50360
• 折射率: 1.582
• 储存条件: 2-8°C，密封，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XT5748000 CHEMICAL NAME : p-Toluenesulfonamide, N,N'-ethylenebis- CAS REGISTRY NUMBER : 4403-78-5 BEILSTEIN REFERENCE NO. : 2399549 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C16-H20-N2-O4-S2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,41,1953

安全

• 海关编码: 2935009090

合成路线

107-15-3 98-59-9 ~99% 4403-78-5

文献：Fukudome, Yasuhiro; Naito, Hiroyuki; Hata, Takeshi; Urabe, Hirokazu Journal of the American Chemical Society, 2008 , vol. 130, # 6 p. 1820 - 1821

64773-90-6 ~% 4403-78-5

文献：Iwata, Masaaki; Kuzuhara, Hiroyoshi Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 11 p. 3395 - 3396

1821-99-4 98-59-9 ~78% 4403-78-5

文献：Mizhiritskii, M. D.; Reikhsfel'd, V. O. J. Gen. Chem. USSR (Engl. Transl.), 1986 , vol. 56, # 7 p. 1547 - 1558,1373 - 1382

70-55-3 106-93-4 ~% 4403-78-5

文献：Howard; Marckwald Chemische Berichte, 1899 , vol. 32, p. 2035

14034-59-4 98-88-4 98-59-9 ~% 644-33-7 详细

文献：Barrett, Anthony G. M.; Lana, J. Carlos A.; Tograie, Shahrzad Journal of the Chemical Society, Chemical Communications, 1980 , # 7 p. 300 - 301

98-59-9 ~% 4403-78-5

文献：Peacock; Dutta Journal of the Chemical Society, 1934 , p. 1303

1080-44-0 ~% 50-00-0 4403-78-5 104-15-4 详细

文献：Hill, Roger R.; Jeffs, Graham E.; Roberts, David R.; Wood, Sharon A. Chemical Communications, 1999 , # 17 p. 1735 - 1736

上下游产品

上游产品  9
107-15-3 98-59-9 64773-90-6 1821-99-4
70-55-3 106-93-4 14034-59-4 98-88-4
1080-44-0
下游产品  7
56187-04-3 55442-07-4 17046-84-3 66821-82-7
821785-00-6 836637-10-6 52667-89-7

海关

海关编码	2935009090
中文概述	2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
申报要素	品名, 成分含量, 用途
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%