59857-86-2

• 常用中文名：1-甲基-2-氧代吡咯烷-4-甲酸甲酯
• 常用英文名：Methyl 1-Methyl-2-oxopyrrolidine-4-carboxylate
• CAS号：59857-86-2
• 分子式：C₇H₁₁NO₃
• 分子量：157.16700
• 发布时间：2018-12-27 16:47:37
• 更新时间：2026-07-05 19:12:31

名称

• 中文名: 1-甲基-5-氧代吡咯烷-3-羧酸甲酯
• 英文名: Methyl 1-methyl-5-oxopyrrolidine-3-carboxylate
• 中文别名: 甲基1-甲基-5-羰基吡咯烷-3-羧酸酯; 5-氧代-1-甲基-吡咯烷-3-羧酸甲酯; 1-甲基-5-氧代吡咯烷-3-甲酸甲酯; 1-甲基-4-甲氧基羰基-2-吡咯烷酮; 1-甲基-5-氧代-3-吡咯烷羧酸甲酯; 3-吡咯烷羧酸,1-甲基-5-氧代-,甲酯; 甲基 1-甲基-5-羰基吡咯烷-3-羧酸酯
• 英文别名: Methyl1-methyl-5-oxopyrrolidine-3-cboxylate; Methyl 1-Methyl-2-oxopyrrolidine-4-cboxylate; 5-keto-1-methyl-pyrrolidine-3-cboxylic acid methyl ester; methyl 1-methyl-5-oxo-3-pyrrolidinecboxylate; Methyl 1-methylpyrrolidin-5-one-3-cboxylate; 3-Pyrrolidinecboxylic acid, 1-methyl-5-oxo-, methyl ester; 1-Methyl-5-oxopyrrolidine-3-cboxylic acid methyl ester; methyl 1-methyl-5-oxopyrrolidine-3-carboxylate; 1-Methyl-5-oxo-3-pyrrolidinecboxylic acid methyl ester; Methyl 1-methylpyrrolidin-2-one-4-cboxylate

物化性质

• 密度: 1.173g/cm3
• 沸点: 263.7ºC at 760 mmHg
• 分子式: C₇H₁₁NO₃
• 分子量: 157.16700
• 闪点: 113.3ºC
• 精确质量: 157.07400
• PSA: 46.61000
• 折射率: 1.476
• 储存条件: 室温，干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UY0557000 CHEMICAL NAME : 3-Pyrrolidinecarboxylic acid, 1-methyl-5-oxo-, methyl ester CAS REGISTRY NUMBER : 59857-86-2 BEILSTEIN REFERENCE NO. : 0473460 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C7-H11-N-O3 MOLECULAR WEIGHT : 157.19 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit REFERENCE : CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 38,2308,1990 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 38,2308,1990

安全

• 海关编码: 2933790090

合成路线

67-56-1 42346-68-9 ~% 59857-86-2

文献：CLARIANT FINANCE (BVI) LIMITED; Wacker, Andreas; Hess, Joachim; Kupfer, Rainer; Roesch, Alexander Patent: US2013/217579 A1, 2013 ; Location in patent: Paragraph 0078 ;

617-52-7 74-89-5 ~92% 59857-86-2

文献：Stanetty, Peter; Turner, Martin; Mihovilovic, Marko D. Molecules, 2005 , vol. 10, # 2 p. 367 - 375

173853-91-3 ~58% 59857-86-2

文献：Fishwick, Colin W. G.; Foster, Richard J.; Carr, Robin E. Tetrahedron Letters, 1995 , vol. 36, # 51 p. 9409 - 9412

上下游产品

上游产品  5
67-56-1 42346-68-9 617-52-7 74-89-5
173853-91-3
下游产品  4
42346-68-9 174747-39-8 59857-92-0 59887-20-6

海关

海关编码	2933790090
中文概述	2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:9.0% 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%