99291-24-4

• 常用中文名：左羟丙哌嗪
• 常用英文名：Levodropropizine
• CAS号：99291-24-4
• 分子式：C₁₃H₂₀N₂O₂
• 分子量：236.310
• 相关类别： 医药中间体 杂环化合物 哌嗪类化合物
• 发布时间：2018-02-24 08:00:00
• 更新时间：2024-01-04 19:47:23

名称

• 中文名: 醋酸甲羟孕酮杂质F
• 英文名: (2R)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol
• 中文别名: 左羟丙哌嗪; S(-)-3-(4-苯基-1-哌嗪)-1,2-丙二醇
• 英文别名: (S)-dropropizine; Levdropropizina; 1,2-Propanediol,3-(4-phenyl-1-piperazinyl)-,(R); (-)-Dropropizine; rapitux; 1,2-Propanediol, 3-(4-phenyl-1-piperazinyl)-, (2S)-; (+)-Dropropizine; (2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol; (R)-3-(4-Phenylpiperazin-1-yl)propane-1,2-diol; Levdropropizina [Latin,Spanish]; MFCD00866852; (2S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol; (R)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol; Levodropropizine; Dropropizine S-form

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 412.7±34.0 °C at 760 mmHg
• 分子式: C₁₃H₂₀N₂O₂
• 分子量: 236.310
• 闪点: 220.9±24.3 °C
• 精确质量: 236.152481
• PSA: 46.94000
• LogP: 0.46
• 外观性状: 白色或灰白色结晶粉末
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.577
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TZ1074950 CHEMICAL NAME : 1,2-Propanediol, 3-(4-phenyl-1-piperazinyl)-, (R)- CAS REGISTRY NUMBER : 99291-24-4 BEILSTEIN REFERENCE NO. : 3592398 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C13-H20-N2-O2 MOLECULAR WEIGHT : 236.35 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 721 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4699911 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 363 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4699911 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 872 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4699911 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 319 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4699911