Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Levodropropizine
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Purity: 99.0%
Stocking Period: 10 Day
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99291-24-4

99291-24-4 structure

99291-24-4 structure

Name: Levodropropizine
Chemical Name: (2R)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol
CAS Number: 99291-24-4
Molecular Formula: C₁₃H₂₀N₂O₂
Molecular Weight: 236.310
Catalog: Pharmaceutical intermediate Heterocyclic compound Piperazine
Create Date: 2018-02-24 08:00:00
Modify Date: 2025-08-27 03:55:36

Name	(2R)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol
Synonyms	(S)-dropropizine Levdropropizina 1,2-Propanediol,3-(4-phenyl-1-piperazinyl)-,(R) (-)-Dropropizine rapitux 1,2-Propanediol, 3-(4-phenyl-1-piperazinyl)-, (2S)- (+)-Dropropizine (2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol (R)-3-(4-Phenylpiperazin-1-yl)propane-1,2-diol Levdropropizina [Latin,Spanish] MFCD00866852 (2S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol (R)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol Levodropropizine Dropropizine S-form

Density	1.2±0.1 g/cm3
Boiling Point	412.7±34.0 °C at 760 mmHg
Molecular Formula	C₁₃H₂₀N₂O₂
Molecular Weight	236.310
Flash Point	220.9±24.3 °C
Exact Mass	236.152481
PSA	46.94000
LogP	0.46
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.577
Storage condition	2-8°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TZ1074950

CHEMICAL NAME :: 1,2-Propanediol, 3-(4-phenyl-1-piperazinyl)-, (R)-

CAS REGISTRY NUMBER :: 99291-24-4

BEILSTEIN REFERENCE NO. :: 3592398

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C13-H20-N2-O2

MOLECULAR WEIGHT :: 236.35

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 721 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4699911

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 363 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4699911

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 872 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4699911

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 319 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4699911

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