176504-90-8

• 常用中文名：N-[(1S)-3-(二甲氧基亚膦酰)-2-氧代-1-(苯基甲基)丙基]-氨基甲酸叔丁酯
• 常用英文名：DIMETHYL ((3S)-4-PHENYL-3-(BOC-AMINO)-2-OXOBUTYL)PHOSPHONATE
• CAS号：176504-90-8
• 分子式：C₁₇H₂₆NO₆P
• 分子量：371.36500
• 发布时间：2017-01-10 00:33:45
• 更新时间：2026-09-06 18:13:06

名称

• 中文名: N-[(1S)-3-(二甲氧基亚膦酰)-2-氧代-1-(苯基甲基)丙基]-氨基甲酸叔丁酯
• 英文名: tert-butyl N-[(2S)-4-dimethoxyphosphoryl-3-oxo-1-phenylbutan-2-yl]carbamate
• 中文别名: (R)-(4-(二甲氧基磷酰基)-3-氧代-1-苯基丁-2-基)氨基甲酸叔丁酯; (3S)-4-苯基-3-(Boc-氨基)-2-氧代丁基)膦酸二甲酯
• 英文别名: Dimethyl((3S)-4-phenyl-3-(Boc-amino)-2-oxobutyl)phosphonate (TLC); Cbamic acid, N-[(1S)-3-(dimethoxyphosphinyl)-2-oxo-1-(phenylmethyl)propyl]-, 1,1-dimethylethyl ester; Dimethyl((3S)-4-phenyl-3-(Boc-amino)-2-oxobutyl)phosphonate; Tert-butyl (R)-(4-(dimethoxyphosphoryl)-3-oxo-1-phenylbutan-2-yl)cbamate; tert-butyl N-[(2S)-4-dimethoxyphosphoryl-3-oxo-1-phenylbutan-2-yl]cbamate; dimethyl [(3S)-4-phenyl-3-[N-(tert-butyloxycarbonyl)amino]-2-oxobutyl]phosphonate; dimethyl (S)-3-tert-butoxycarbonylamino-2-oxo-4-phenylbutylphosphonate; ((S)-3-tert-butoxycarbonylamino-2-oxo-4-phenylbutyl)phosphonic acid dimethyl ester; (S)-tert-butyl 4-(dimethoxyphosphoryl)-3-oxo-1-phenylbutan-2-ylcarbamate; dimethyl (3S)-3-[(tert-butoxycarbonyl)amino]-2-oxo-4-phenylbutylphosphonate; dimethyl [(3S)-3-[N-(tert-butoxycarbonyl)amino]-2-oxo-4-phenylbutyl]phosphonate; dimethyl [(3S)-4-phenyl-3-[(tert-butyloxycarbonyl)amino]-2-oxobutyl]phosphonate

物化性质

• 分子式: C₁₇H₂₆NO₆P
• 分子量: 371.36500
• 精确质量: 371.15000
• PSA: 104.23000
• LogP: 3.38180

合成路线

51987-73-6 756-79-6 ~93% 176504-90-8

文献：Tossi, Alessandro; Benedetti, Fabio; Norbedo, Stefano; Skrbec, Damiano; Berti, Federico; Romeo, Domenico Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 22 p. 4719 - 4727

13734-34-4 756-79-6 ~89% 176504-90-8

文献：Benedetti, Fabio; Berti, Federico; Budal, Sara; Campaner, Pietro; Dinon, Francesca; Tossi, Alessandro; Argirova, Radka; Genova, Petia; Atanassov, Vasil; Hinkov, Anton Journal of Medicinal Chemistry, 2012 , vol. 55, # 8 p. 3900 - 3910

13734-34-4 ~% 176504-90-8

文献：Rodriguez, Ana Chiva; Ramos, Anna Pico; Hawkes, Geoffrey E.; Berti, Federico; Resmini, Marina Tetrahedron Asymmetry, 2004 , vol. 15, # 12 p. 1847 - 1855

51987-73-6 34939-91-8 ~% 176504-90-8

文献：Benedetti; Miertus; Norbedo; Tossi; Zlatoidzky Journal of Organic Chemistry, 1997 , vol. 62, # 26 p. 9348 - 9353

63-91-2 ~% 176504-90-8

文献：Nchinda, Aloysius T.; Chibale, Kelly; Redelinghuys, Pierre; Sturrock, Edward D. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 17 p. 4612 - 4615

24424-99-5 ~% 176504-90-8

文献：Nchinda, Aloysius T.; Chibale, Kelly; Redelinghuys, Pierre; Sturrock, Edward D. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 17 p. 4612 - 4615

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