145514-62-1

• 常用中文名：(2R,3S)-3-叔丁氧基羰基氨基-2-羟基-3-苯基丙酸
• 常用英文名：(2R,3S)-Boc-3-Phenylisoserine
• CAS号：145514-62-1
• 分子式：C₁₄H₁₉NO₅
• 分子量：281.30400
• 发布时间：2019-01-01 13:06:44
• 更新时间：2026-08-09 00:49:36

名称

• 中文名: (2R,3S)-3-叔丁氧甲酰胺基-2-羟基-3-苯基-丙胺酸
• 英文名: (2R,3S)-N-Boc-3-Phenylisoserine
• 中文别名: 多西他赛相关化合物2; 多西侧链酸3; DT-4的水解产物; (2R,3S)-BOC-3-苯基异丝氨酸; 卡巴他赛杂质10; (2R,3S)-N-叔丁氧羰基-3-苯基异丝氨酸; 多西他赛相关化合物2((2R,3S)-BOC-3-苯基异丝氨酸); (2R,3S)-N-BOC-3-苯基异丝氨酸; 卡巴他赛杂质P; 卡巴他赛杂质QS; 卡巴他赛杂质39; 3S)-3-叔丁氧基羰基氨基-2-羟基-3-苯基丙酸
• 英文别名: (2R,3S)-3-(Boc-amino)-2-hydroxy-3-phenylpropanic acid; (2R,3S)-3-t-butoxycbony-cbonylaMino-2-hydroxy-3-phenylpropinacid; (2R,3S)-N-Boc-3-Phenyl-isoserine; SIDE CHAINS OF DOCETAXEL-4; Docetaxel 16; Boc-3-Phenylisoserine; Docetaxel Related Compound 2 ((2R, 3S)-Boc-3-Phenylisoserine); N-Boc-(2R,3R)-3-amino-2-hydroxy-3-phenylpropionic acid (HPLC); N-(Tert-Butoxy)carbonyl (2R,3R)-3-Amino-2-hydroxy-3-phenylpropionic acid; (2R,3S)-3-(N-T-BUTOXYCBONYL-AMINO)-2-HYDROXY-3-PHENYL-PROPANOIC ACID; BOC-ISE(3-PHENYL)-OH; MFCD02684461; Boc-3-Phenylisoserine/ (2R,3S)-N-Boc-3-phenylisoserine; (2R,3S)-3-((tert-butoxycbonyl)amino)-2-hydroxy-3-phenylpropanoic acid; (2R,3S)-3-(Boc-amino)-2-hydroxy-3-phenyl-propanoic; (2R,3S)-3-(BOC-AMINO)-2-HYDROXY-3-PHENYL-PROPANOIC ACID; N-Boc-(2R,3R)-3-amino-2-hydroxy-3-phenylpropionic acid; (2R,3S)-3-t-butoxy-cbonylamino-2-hydroxy-3-phenylpropionacid; Docetaxel Related Compound 2; BOC-(2R,3S)-3-PHENYLISOSERINE; N-BOC-(2R,3R)-3-AMINO-2-HYDROXY-3-PHENYL-PROPIONIC ACID; 2R,3S)-3-t-butoxy-cbonylaMino-2-hydroxy-3-phenylpropinacid; benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (αR,βS); (2R,3S)-3-tert-Butoxycbonylamino-2-hydroxy-3-phenylpropion acid; Boc-(2R,3S)-3-phenylisoserine (HPLC); (2R, 3S) -3-tert butoxycbonylamino-2-hydroxy-3-phenylpropionic acid; (2R,3S)-N-T-BUTOXYCBONYL-3-PHENYLISOSERINE; (2R,3S)-BOC-3-PHENYLISOSERINE

物化性质

• 密度: 1.239g/cm3
• 沸点: 470.4ºC at 760 mmHg
• 分子式: C₁₄H₁₉NO₅
• 分子量: 281.30400
• 闪点: 238.3ºC
• 精确质量: 281.12600
• PSA: 95.86000
• LogP: 2.08880
• 外观性状: 粉末
• 蒸汽压: 1.19E-09mmHg at 25°C
• 折射率: 1.547
• 储存条件: -15°C

安全

• 危害码 (欧洲): Xi

合成路线

24424-99-5 132201-32-2 ~89% 145514-62-1

文献：Shen, Xin; Yang, Jidong; Zhan, Huaxing; Wang, Hu; Wu, Shaohong; Chen, Zili Chinese Journal of Chemistry, 2013 , vol. 31, # 1 p. 31 - 36

479078-61-0 ~% 145514-62-1

文献：Synlett, , # 10 p. 1665 - 1668

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