132388-64-8

• 常用中文名：L-天门冬二氨酸
• 常用英文名：Fmoc-Asn(Trt)-OPfp
• CAS号：132388-64-8
• 分子式：C₄₄H₃₁F₅N₂O₅
• 分子量：762.71900
• 相关类别： 生物化工 氨基酸及其衍生物 天冬酰胺类衍生物
• 发布时间：2018-02-06 08:00:00
• 更新时间：2026-07-03 12:23:47
• 静脉注射可引起血压下降, 外周血管扩张, 心收缩力增强, 心率变慢和尿量增加[4]。幽门结扎大鼠口服时, 能阻止口服乙酰基水杨酸引起的胃粘膜损伤[5,6]。动物试验表明有显著镇咳作用和一定的平喘作用[2]。

名称

• 中文名: N-Alpha-Fmoc-N-β-三苯甲基-L-冬酰胺酸五氟苯酯
• 英文名: (2,3,4,5,6-pentafluorophenyl) (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-(tritylamino)butanoate
• 中文别名: 天冬酰胺; Α-氨基琥珀酰氨酸; N-Α-FMOC-N-Β-三苯甲基-L-冬酰胺酸五氟苯酯; N-芴甲氧羰基-N'-三苯甲基-L-天门冬酰胺五氟苯酯; (S)-2-((((9H-芴-9-基)甲氧基)羰基)氨基)-4-氧代-4-(三苯甲基氨基)丁酸全氟苯基酯; N-Α-FMOC-N-Β-三苯甲基-L-天冬酰胺五氟苯酯; 2-氨基-3-甲酰胺基丙酸
• 英文别名: 2-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]-4-oxo-4-[(triphenylmethyl)amino]butanoic acid (2,3,4,5,6-pentafluorophenyl) ester; FMOC-ASN(TRT)-OPFP; N-ALPHA-FMOC-N-BETA-TRITYL-L-ASPAGINE PENTAFLUORPHENYL ESTER; (2,3,4,5,6-pentafluorophenyl)(2S)-2-(9H-fluoren-9-ylmethoxycbonylamino)-4-oxo-4-(tritylamino)butanoate; FMOC-ASN(TRT)-OPFP //BP; 2,3,4,5,6-pentafluorophenyl (2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-[(triphenylmethyl)cbamoyl]propanoate; N-alpha-FMoc-beta-trityl-L-aspagine pentafluorophenyl ester; FMOC-N-BETA-TRITYL-L-ASPAGINE PENTAFLUOROPHENYL ESTER; L-Aspagine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)-, 2,3,4,5,6-pentafluorophenyl ester; N-Fmoc-N'-trityl-L-asparagine pentafluorophenyl ester; N-α-Fmoc-N-β-trityl-L-aspagine pentafluorophenyl ester; pentafluorophenyl ester; fmoc-asn(trt)-opfp; FMOC-L-ASN(TRT)-OPFP; (9H-Fluoren-9-yl)MethOxy]carbonyl Asn(Trt)-Opfp; N2-Fmoc-N4-trityl-L-aspagine pentafluorophenyl ester; N-ALPHA-FMOC-N-BETA-TRITYL-L-ASPAGINE PENTAFLUOROPHENYL ESTER; NALPHA-9-Fluorenylmethoxycbonyl-NB-trityl-L-aspagine pentafluorophenyl; (S)-Perfluorophenyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-(tritylamino)butanoate; FMOC-ASPAGINE(TRT)-OPFP; N-|A-Fmoc-N-|A-trityl-L-asparagine pentafluorophenyl ester; FMOC-N-GAMMA-TRITYL-L-ASPAGINE PENTAFLUOROPHENYL ESTER; (S)-perfluorophenyl 2-(((9H-fluoren-9-yl)methoxy)cbonylamino)-4-oxo-4-(tritylamino)butanoate; (S)-Perfluorophenyl 2-((((9H-fluoren-9-yl)methoxy)-carbonyl)amino)-4-oxo-4-(tritylamino)butano; N-^a-Fmoc-N-^b-trityl-L-aspagine pentafluorophenyl ester; Fmoc-Asn(Trt) pentafluorophenyl ester

物化性质

• 密度: 1.3g/cm3
• 沸点: 813.2ºC at 760mmHg
• 分子式: C₄₄H₃₁F₅N₂O₅
• 分子量: 762.71900
• 闪点: 445.6ºC
• 精确质量: 762.21500
• PSA: 93.73000
• LogP: 9.47500
• 蒸汽压: 1.61E-26mmHg at 25°C
• 折射率: 1.6
• 储存条件: -20°C

安全

• 危害码 (欧洲): Xi

合成路线

76-84-6 ~% 132388-64-8

文献：Tetrahedron Letters, , vol. 32, # 6 p. 739 - 742

132388-57-9 ~% 132388-64-8

文献：Tetrahedron Letters, , vol. 32, # 6 p. 739 - 742

132388-58-0 ~% 132388-64-8

文献：Tetrahedron Letters, , vol. 32, # 6 p. 739 - 742

771-61-9 132388-59-1 ~% 132388-64-8

文献：Tetrahedron Letters, , vol. 32, # 6 p. 739 - 742

上下游产品

上游产品  5
76-84-6 132388-57-9 132388-58-0 771-61-9
132388-59-1
下游产品  0