毒理学数据:
1 。
试验方法：行政到眼睛
摄入剂量： 100 mg/24H
测试对象：啮齿动物-兔
毒性类型： SkinEyeIrrition
毒性作用：轻微的
2 。
试验方法：口服
摄入剂量： 3570毫克/千克
测试对象：人力
毒性类型：急性
毒性作用： 1.溃疡或出血，胃
3 。
试验方法：口服
摄入剂量： 1420年毫克/千克
测试对象：啮齿动物-鼠
毒性类型：急性
毒性作用： 1.嗜睡（普通抑郁活动）
2.肺，胸部或呼吸-急性肺水肿
3.其他变化
生态学数据:
该物质对环境可能有危害，对水体应给予特别注意。其粉尘能强烈刺激眼睛、皮肤和呼吸系统。对胃肠道有刺激作用。
CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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XZ1900000
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CHEMICAL NAME :
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s-Triazine-2,4,6(1H,3H,5H)-trione, dichloro-, sodium salt
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CAS REGISTRY NUMBER :
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2893-78-9
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LAST UPDATED :
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199806
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DATA ITEMS CITED :
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17
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MOLECULAR FORMULA :
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C3-H-Cl2-N3-O3.Na
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MOLECULAR WEIGHT :
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220.96
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WISWESSER LINE NOTATION :
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T6MVNVNVJ CG GG &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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REFERENCE :
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MONS** Monsanto Co. Toxicity Information. (Monsanto Industrial Chemicals Co., Bancroft Bldg., Suite 204, 3411 Silverside Rd., Wilmington, DE 19810) Volume(issue)/page/year: -,-,1972
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TYPE OF TEST :
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Standard Draize test
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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REFERENCE :
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34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,167,1969
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TYPE OF TEST :
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Rinsed with water
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ROUTE OF EXPOSURE :
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Administration into the eye
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SPECIES OBSERVED :
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Rodent - rabbit
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REFERENCE :
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MONS** Monsanto Co. Toxicity Information. (Monsanto Industrial Chemicals Co., Bancroft Bldg., Suite 204, 3411 Silverside Rd., Wilmington, DE 19810) Volume(issue)/page/year: -,-,1972
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TYPE OF TEST :
-
Standard Draize test
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ROUTE OF EXPOSURE :
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Administration into the eye
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SPECIES OBSERVED :
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Rodent - rabbit
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REFERENCE :
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NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555174 ** ACUTE TOXICITY DATA **
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human
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DOSE/DURATION :
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3570 mg/kg
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TOXIC EFFECTS :
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Gastrointestinal - ulceration or bleeding from stomach
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REFERENCE :
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34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,167,1969
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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1420 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - acute pulmonary edema Liver - other changes
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REFERENCE :
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NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555174
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TYPE OF TEST :
-
LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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2500 mg/kg
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TOXIC EFFECTS :
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Sense Organs and Special Senses (Eye) - lacrimation Behavioral - coma Lungs, Thorax, or Respiration - dyspnea
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REFERENCE :
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MONS** Monsanto Co. Toxicity Information. (Monsanto Industrial Chemicals Co., Bancroft Bldg., Suite 204, 3411 Silverside Rd., Wilmington, DE 19810) Volume(issue)/page/year: -,-,1972
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TYPE OF TEST :
-
LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Administration onto the skin
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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3160 mg/kg
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TOXIC EFFECTS :
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Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - pulmonary emboli Liver - other changes
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REFERENCE :
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NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0555174
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Mammal - species unspecified
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DOSE/DURATION :
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1670 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 31,959,1980 ** REPRODUCTIVE DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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4 gm/kg
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SEX/DURATION :
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female 6-15 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Effects on Newborn - physical
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REFERENCE :
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YKRYAH Yakubutsu Ryoho. Medicinal Treatment. (Tokyo, Japan) V.1-14, 1968-81. Suspended. Volume(issue)/page/year: 13,353,1980
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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4 gm/kg
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SEX/DURATION :
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female 6-15 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - musculoskeletal system Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - physical
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REFERENCE :
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YKRYAH Yakubutsu Ryoho. Medicinal Treatment. (Tokyo, Japan) V.1-14, 1968-81. Suspended. Volume(issue)/page/year: 13,23,1980 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1492 No. of Facilities: 6526 (estimated) No. of Industries: 29 No. of Occupations: 27 No. of Employees: 39204 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M1492 No. of Facilities: 3499 (estimated) No. of Industries: 33 No. of Occupations: 38 No. of Employees: 53851 (estimated) No. of Female Employees: 24172 (estimated)
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