301-13-3

• 常用中文名：亚磷酸三(2-乙基己基)酯
• 常用英文名：Phosphorous acid,tris(2-ethylhexyl) ester
• CAS号：301-13-3
• 分子式：C₂₄H₅₁O₃P
• 分子量：418.63400
• 发布时间：2018-02-09 08:00:00
• 更新时间：2024-01-11 10:04:29
• 下载msds

名称

• 中文名: 亚磷酸三(2-乙基己基)酯
• 英文名: tris(2-ethylhexyl) phosphite
• 中文别名: 三(2-乙基己基)亚磷酸酯; 三(2-乙基己基)亚磷酸盐
• 英文别名: PHOSPHOROUS ACID TRIS(2-ETHYLHEXYL) ESTER; Trioctyl Phosphite; Phosphorous Acid Trioctyl Ester; JP 308; EINECS 206-111-2

物化性质

• 沸点: 446.7ºC at 760mmHg
• 分子式: C₂₄H₅₁O₃P
• 分子量: 418.63400
• 闪点: 278.6ºC
• 精确质量: 418.35800
• PSA: 41.28000
• LogP: 8.91230
• 储存条件: 室温
• 计算化学:

  1.疏水参数计算参考值（XlogP）:9.5

  2.氢键供体数量:0

  3.氢键受体数量:3

  4.可旋转化学键数量:21

  5.互变异构体数量:无

  6.拓扑分子极性表面积27.7

  7.重原子数量:28

  8.表面电荷:0

  9.复杂度:267

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:3

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  一、物性数据

  性状：不可用

  密度（g/mL,25/4℃）：0.89

  相对蒸汽密度（g/mL,空气=1）：不可用

  熔点（ºC）：不可用

  沸点（ºC,常压）：不可用

  沸点（ºC,5.2kPa）：不可用

  折射率：不可用

  闪点（ºC）： 194 比旋光度（º）： 不可用

  自燃点或引燃温度（ºC）：不可用

  蒸气压（kPa,25ºC）：不可用

  饱和蒸气压（kPa,60ºC）：不可用

  燃烧热（KJ/mol）：不可用

  临界温度（ºC）：不可用

  临界压力（KPa）：不可用

  油水（辛醇/水）分配系数的对数值：不可用

  爆炸上限（%,V/V）：不可用

  爆炸下限（%,V/V）：不可用

  溶解性：不可用

MSDS

Tris(2-ethylhexyl) Phosphite Revision number: 5 SAFETY DATA SHEET Section1. IDENTIFICATION Product name:Tris(2-ethylhexyl) Phosphite Revision number:5 Section2. HAZARDS IDENTIFICATION GHS classification PHYSICAL HAZARDSNot classified HEALTH HAZARDS Acute toxicity (Dermal)Category 5 Category 2 Skin corrosion/irritation Serious eye damage/eye irritationCategory 2A Not classified ENVIRONMENTAL HAZARDS GHS label elements, including precautionary statements Pictograms or hazard symbols Signal wordWarning Hazard statementsMay be harmful in contact with skin Causes skin irritation Causes serious eye irritation Precautionary statements: Wash hands thoroughly after handling. [Prevention] Wear protective gloves/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, [Response] if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. IF ON SKIN: Gently wash with plenty of soap and water. If skin irritation occurs: Get medical advice/attention. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substance/mixture:Substance Components:Tris(2-ethylhexyl) Phosphite Percent:>90.0%(GC) CAS Number:301-13-3 Phosphorous Acid Trioctyl Ester , Phosphorous Acid Tris(2-ethylhexyl) Ester , Synonyms: Trioctyl Phosphite Chemical Formula:C24H51O3P Tris(2-ethylhexyl) Phosphite Section4. FIRST AID MEASURES Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician if you feel unwell. Skin contact:Remove/Take off immediately all contaminated clothing. Gently wash with plenty of soap and water. If skin irritation or rash occurs: Get medical advice/attention. Eye contact:Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Ingestion:Call a POISON CENTER or doctor/physician if you feel unwell. Rinse mouth. A rescuer should wear personal protective equipment, such as rubber gloves and air- Protection of first-aiders: tight goggles. Section5. FIRE-FIGHTING MEASURES Suitable extinguishingDry chemical, foam, carbon dioxide. media: Unsuitable extinguishing Water (It may scatter and spread fire.) media: Specific hazards arising Take care as it may decompose upon combustion or in high temperatures to from the chemical:generate poisonous fume. Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so. Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment. equipment for firefighters: Section6. ACCIDENTAL RELEASE MEASURES Personal precautions,Use personal protective equipment. Keep people away from and upwind of spill/leak. protective equipment and Ensure adequate ventilation. Entry to non-involved personnel should be controlled emergency procedures: around the leakage area by roping off, etc. Environmental precautions: Prevent product from entering drains. Methods and materials for Absorb spilled material in a suitable absorbent (e.g. rag, dry sand, earth, saw-dust). containment and cleaning In case of large amount of spillage, contain a spill by bunding. Adhered or collected up: material should be promptly disposed of, in accordance with appropriate laws and regulations. Section7. HANDLING AND STORAGE Precautions for safe handling Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment. Prevent generation of vapour or mist. Wash hands and face thoroughly after handling. Use a ventilation, local exhaust if vapour or aerosol will be generated. Advice on safe handling: Avoid contact with skin, eyes and clothing. Conditions for safe storage, including any incompatibilities Keep container tightly closed. Store in a cool and dark place. Storage conditions: Store under inert gas. Protect from moisture. Store away from incompatible materials such as oxidizing agents. Moisture-sensitive Packaging material:Comply with laws. Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION Engineering controls:Install a closed system or local exhaust as possible so that workers should not be exposed directly. Also install safety shower and eye bath. Personal protective equipment Respiratory protection: Vapor respirator. Follow local and national regulations. Tris(2-ethylhexyl) Phosphite Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION Hand protection:Protective gloves. Eye protection:Safety glasses. A face-shield, if the situation requires. Skin and body protection: Protective clothing. Protective boots, if the situation requires. Section9. PHYSICAL AND CHEMICAL PROPERTIES Physical state (20°C):Liquid Clear Form: Colour:Colorless - Very pale yellow Odour:No data available pH: No data available Melting point/freezing point:No data available Boiling point/range:No data available Flash point:194°C Flammability or explosive limits: Lower:No data available Upper:No data available Relative density:0.89 Solubility(ies): [Water]No data available [Other solvents]No data available Section10. STABILITY AND REACTIVITY Stable under proper conditions. Chemical stability: Possibility of hazardous No special reactivity has been reported. reactions: Incompatible materials: Oxidizing agents Hazardous decomposition Carbon monoxide, Carbon dioxide, Phosphorus oxides products: Section11. TOXICOLOGICAL INFORMATION ihl-rat LC50:>20 g/m3 Acute Toxicity: orl-rat LD50:6200 mg/kg skn-rbt LD50:>5 g/kg Skin corrosion/irritation: No data available Serious eyeNo data available damage/irritation: Germ cell mutagenicity: No data available Carcinogenicity: IARC =No data available NTP =No data available Reproductive toxicity:No data available RTECS Number:TH2090000 Section12. ECOLOGICAL INFORMATION Ecotoxicity: No data available Fish: Crustacea:No data available No data available Algae: Persistence / degradability: No data available No data available Bioaccumulative potential(BCF): Mobility in soil Log Pow:No data available No data available Soil adsorption (Koc): Tris(2-ethylhexyl) Phosphite Section12. ECOLOGICAL INFORMATION Henry's LawNo data available constant(PaM3/mol): Section13. DISPOSAL CONSIDERATIONS Recycle to process, if possible. Consult your local regional authorities. You may be able to burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section14. TRANSPORT INFORMATION Hazards Class:Does not correspond to the classification standard of the United Nations Not listed UN-No: Section15. REGULATORY INFORMATION Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002 and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were prescribed. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

毒理学数据: 二、毒理学数据： 急性毒性：不可用。 生态学数据: 三、生态学数据： 1、其它有害作用：该物质对环境可能有危害，对水体应给予特别注意。 CHEMICAL IDENTIFICATION RTECS NUMBER : TH2090000 CHEMICAL NAME : Phosphorous acid, tris(2-ethylhexyl) ester CAS REGISTRY NUMBER : 301-13-3 BEILSTEIN REFERENCE NO. : 1712332 LAST UPDATED : 199806 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C24-H51-O3-P HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 6200 mg/kg TOXIC EFFECTS : Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity) Behavioral - tremor REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(12),51,1981 TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >20 gm/m3 TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ALBRW* Albright & Wilson Inc. (P.O. Box 26229, Richmond, VA 23260-6229) Volume(issue)/page/year: #OPB-3,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 7600 mg/kg TOXIC EFFECTS : Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity) Behavioral - tremor REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(12),51,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 8500 mg/kg TOXIC EFFECTS : Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - somnolence (general depressed activity) Behavioral - tremor REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(12),51,1981 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ALBRW* Albright & Wilson Inc. (P.O. Box 26229, Richmond, VA 23260-6229) Volume(issue)/page/year: #OPB-3,1984 TYPE OF TEST : LC - Lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : >27500 ug/m3 TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(12),51,1981 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7 mg/m3/4H/22W-I TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other oxidoreductases REFERENCE : GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(12),51,1981

安全

• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): S26-S36-S37-S39
• 海关编码: 2920901900

合成路线

104-76-7 ~% 301-13-3

文献：US2678940 , ;

104-76-7 2283-11-6 ~% 301-13-3

文献：J. Gen. Chem. USSR (Engl. Transl.), , vol. 31, p. 2377 - 2380,2214 - 2217 Journal fuer Praktische Chemie (Leipzig), , vol. 22, p. 186 - 191

104-76-7 2632-88-4 ~% 301-13-3

文献：J. Gen. Chem. USSR (Engl. Transl.), , vol. 31, p. 2377 - 2380,2214 - 2217

上下游产品

上游产品  3
104-76-7 2283-11-6 2632-88-4
下游产品  8
187148-77-2 86-74-8 78-42-2 123-04-6
66258-31-9 136630-39-2 544436-46-6 836682-40-7

海关

海关编码	2920901900
中文概述	2920901900 亚磷酸酯。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2920901900 VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%