50909-86-9

• 常用中文名：腔肠素-H
• 常用英文名：Coelenterazine h
• CAS号：50909-86-9
• 分子式：C₂₆H₂₁N₃O₂
• 分子量：407.464
• 相关类别： 研究领域 其他
• 发布时间：2018-08-07 12:12:06
• 更新时间：2026-06-30 19:00:20
• Coelenterazine h 是 Coelenterazine 的衍生物。 Coelenterazine h 对 Ca2+ 比它的天然复合物更敏感,因此为测量 Ca2+ 浓度的微小变化提供了有价值的工具。

名称

• 中文名: 腔肠素-H
• 英文名: 2,8-dibenzyl-6-(4-hydroxyphenyl)-7H-imidazo[1,2-a]pyrazin-3-one
• 中文别名: 钙离子荧光探针腔肠素; 腔肠素H COELENTERAZINE H; 2,8-二苄基-6-(4-羟基苯基)咪唑并[1,2-A]吡嗪-3(7H)-酮; COELENTERAZINE-H(新增分子); 腔肠荧光素H
• 英文别名: 2,8-DIBENZYL-6-(P-HYDROXYPHENYL)-IMIDAZO[1,2A]PYRAZIN-3-(7H)-ONE; 2,8-dibenzyl-6-(4-hydroxyphenyl)imidazo[1,20-a]pyrazin-3(7H)one; 2-(4-DEHYDROXY)COELENTERAZINE; 2,8-Dibenzyl-6-(4-hydroxyphenyl)imidazo[1,2-a]pyrazin-3(7H)-one; 2,8-dibenzyl-6-(4-hydroxyphenyl)-3H,7H-imidazo[1,2-a]pyrazin-3-one; Renilla luciferin; COELENTERAZINE-H, SYNTHETIC; CLZN-h; Coelenterazine-h,Synthetic; COELENTERAZINE H; 2-DEOXYCOELENTERAZINE; CLZ-H; Colenterazine H; 2-deoxycoelenterazine; 2-Deoxycoelenterazine Luciferin (Renilla); CLZN h [Coelenterazine h]; Benzyl-Coelenterazine h-CTZ; Coelenterazine.UltraPure ade; 2-Deoxycoelenterazine CLZN-h; LUCIFERIN (RENILLA); H-coelenterazine; 2,8-dibenzyl-6-(4-hydroxyphenyl)iMidazo[1,2-a]pyrazin-3(7H)-one; Coelenterazine h solid; CLZN-H; Imidazo[1,2-a]pyrazin-3(7H)-one, 6-(4-hydroxyphenyl)-2,8-bis(phenylmethyl); CLZ-h; 2-BENZYL-6-(P-HYDROXYPHENYL)-8-BENZYLIMIDAZO[1,2-A]PYRAZIN-3-(7H)-ONE; ENTERAZINE H; Inhibitor,Coelenterazine h,inhibit; Renilla Luciferin; coelenterazine-h

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 593.5±60.0 °C at 760 mmHg
• 熔点: 141ºC
• 分子式: C₂₆H₂₁N₃O₂
• 分子量: 407.464
• 闪点: 312.7±32.9 °C
• 精确质量: 407.163391
• PSA: 70.39000
• LogP: 4.60
• 外观性状: 黄色至褐色粉末
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.675
• 储存条件: -20°C

生物活性

• 描述: Coelenterazine h 是 Coelenterazine 的衍生物。 Coelenterazine h 对 Ca2+ 比它的天然复合物更敏感,因此为测量 Ca2+ 浓度的微小变化提供了有价值的工具。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 其他

安全

• 符号: GHS07
• 信号词: Warning
• 危害声明: H315-H319-H335
• 警示性声明: P261-P305 + P351 + P338
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2933990090

合成路线

19256-31-6 40040-81-1 ~28% 50909-86-9

文献：UNIVERSITA DEGLI STUDI DI SIENA; GIULIANI, Germano; CAPPELLI, Andrea; VOMERO, Salvatore; ANZINI, Maurizio Patent: WO2011/7314 A1, 2011 ; Location in patent: Page/Page column 38 ;

1823-76-3 ~% 50909-86-9

文献：Qi, Chen Feng; Gomi, Yasushiro; Hirano, Takashi; Ohashi, Mamoru; Ohmiya, Yoshihiro; Tsuji, Frederick I. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 13 p. 1607 - 1612

55379-75-4 ~% 50909-86-9

文献：Qi, Chen Feng; Gomi, Yasushiro; Hirano, Takashi; Ohashi, Mamoru; Ohmiya, Yoshihiro; Tsuji, Frederick I. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 13 p. 1607 - 1612

123437-73-0 ~% 50909-86-9

文献：Qi, Chen Feng; Gomi, Yasushiro; Hirano, Takashi; Ohashi, Mamoru; Ohmiya, Yoshihiro; Tsuji, Frederick I. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 13 p. 1607 - 1612

108-88-3 ~% 50909-86-9

文献：UNIVERSITA DEGLI STUDI DI SIENA; GIULIANI, Germano; CAPPELLI, Andrea; VOMERO, Salvatore; ANZINI, Maurizio Patent: WO2011/7314 A1, 2011 ;

185148-51-0 ~% 50909-86-9

文献：UNIVERSITA DEGLI STUDI DI SIENA; GIULIANI, Germano; CAPPELLI, Andrea; VOMERO, Salvatore; ANZINI, Maurizio Patent: WO2011/7314 A1, 2011 ;

174680-55-8 ~% 50909-86-9

文献：UNIVERSITA DEGLI STUDI DI SIENA; GIULIANI, Germano; CAPPELLI, Andrea; VOMERO, Salvatore; ANZINI, Maurizio Patent: WO2011/7314 A1, 2011 ;

56485-04-2 37156-84-6 ~% 50909-86-9

文献：Qi, Chen Feng; Gomi, Yasushiro; Hirano, Takashi; Ohashi, Mamoru; Ohmiya, Yoshihiro; Tsuji, Frederick I. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 13 p. 1607 - 1612

40040-81-1 ~% 50909-86-9

文献：Qi, Chen Feng; Gomi, Yasushiro; Hirano, Takashi; Ohashi, Mamoru; Ohmiya, Yoshihiro; Tsuji, Frederick I. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 13 p. 1607 - 1612

上下游产品

上游产品  10
19256-31-6 40040-81-1 1823-76-3 55379-75-4
123437-73-0 108-88-3 185148-51-0 174680-55-8
56485-04-2 37156-84-6
下游产品  0

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%